Catalog No.
RHD29901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
ITGB6, Integrin beta-6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P18564
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Q89
Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin., PMID:40488391
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118
Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis., PMID:37160775
Inhibition of integrin αvβ6 sparks T-cell antitumor response and enhances immune checkpoint blockade therapy in colorectal cancer., PMID:35131862
A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids., PMID:34621667
Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer., PMID:34200100
Identification of cell surface targets for CAR-T cell therapies and antibody-drug conjugates in breast cancer., PMID:33838601
A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations., PMID:30696911
Initiation of fibrosis in the integrin Αvβ6 knockout mice., PMID:30500364
Systemic inhibition of BMP1-3 decreases progression of CCl4-induced liver fibrosis in rats., PMID:29482391
Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density., PMID:29444691
ITGAV (alpha v integrins) bind SPP1 (osteopontin) to support trophoblast cell adhesion., PMID:28250242
Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasion., PMID:26359297
A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure., PMID:25658712
Integrinβ6-targeted immunoliposomes mediate tumor-specific drug delivery and enhance therapeutic efficacy in colon carcinoma., PMID:25549721
Therapeutic targeting of integrin αvβ6 in breast cancer., PMID:24974129
Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis., PMID:24167080
Functional characterization of a porcine emphysema model., PMID:24043489
Longitudinal expression analysis of αv integrins in human gliomas reveals upregulation of integrin αvβ3 as a negative prognostic factor., PMID:23399898
Kidney transplants with progressing chronic diseases express high levels of acute kidney injury transcripts., PMID:23356967
Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice., PMID:19118215
Phenotypic and genetic characterization of a novel phenotype in pigs characterized by juvenile hairlessness and age dependent emphysema., PMID:18549483
Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis., PMID:17916808
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury., PMID:16710477
For research use only. Not for human or drug use.
