Catalog No.
RHD10902
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
FRA-1, FRA1, Fos-related antigen 1, FOSL1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15407
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1P75
Deciphering the history of ERK activity from fixed-cell immunofluorescence measurements., PMID:40399273
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
FOSL1-mediated LINC01566 negatively regulates CD4+ T-cell activation in myasthenia gravis., PMID:39113081
PDGFA-associated protein 1 is a novel target of c-Myc and contributes to colorectal cancer initiation and progression., PMID:35716012
Melatonin inhibits EMT and PD-L1 expression through the ERK1/2/FOSL1 pathway and regulates anti-tumor immunity in HNSCC., PMID:35298069
Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1., PMID:34972106
Differentiating cancer cells reveal early large-scale genome regulation by pericentric domains., PMID:33453273
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease., PMID:31934626
CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages., PMID:31244935
The effect of Helicobacter pylori on the expression of FRA-1 in gastric epithelial cells and its mechanism., PMID:30807813
Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss., PMID:30779858
Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci., PMID:29682593
Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance., PMID:29662190
MicroRNA-195-5p, a new regulator of Fra-1, suppresses the migration and invasion of prostate cancer cells., PMID:26337460
Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation., PMID:25961580
The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells., PMID:25288397
Expression of claudin, paxillin and FRA-1 in non-nodular breast lesions in association with microcalcifications., PMID:23657508
Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in mice., PMID:23576729
Old players with a newly defined function: Fra-1 and c-Fos support growth of human malignant breast tumors by activating membrane biogenesis at the cytoplasm., PMID:23301044
Effects of intermittent hypoxia on leptin signalling in the carotid body., PMID:23201827
Differential glioma-associated tumor antigen expression profiles of human glioma cells grown in hypoxia., PMID:22957023
Increased levels of nuclear factor κB and Fos-related antigen 1 in lung tissues from patients with acute respiratory distress syndrome., PMID:21526963
Role of Fos-related antigen 1 in the progression and prognosis of ductal breast carcinoma., PMID:21371080
Dietary energy restriction, in part through glucocorticoid hormones, mediates the impact of 12-O-tetradecanoylphorbol-13-acetate on jun D and fra-1 in Sencar mouse epidermis., PMID:20232358
The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression., PMID:19966854
Fra-1 regulates vimentin during Ha-RAS-induced epithelial mesenchymal transition in human colon carcinoma cells., PMID:18098284
An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy., PMID:17192200
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells., PMID:16424019
Fos- and Jun-related transcription factors are involved in the signal transduction pathway of mechanical loading in condylar chondrocytes., PMID:16373449
Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells., PMID:16148030
Fra1 activity in the frog, Rana esculenta, testis: a new potential role in sperm transport., PMID:15625234
Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene., PMID:14673133
1alpha,25-dihydroxyvitamin D3 stimulates activator protein 1 DNA-binding activity by a phosphatidylinositol 3-kinase/Ras/MEK/extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1-dependent increase in c-Fos, Fra1, and c-Jun expression in human keratinocytes., PMID:12648218
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers., PMID:12371906
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D., PMID:11254751
Hydrogen peroxide stimulates extracellular signal-regulated protein kinases in pulmonary arterial smooth muscle cells., PMID:9698606
The effects of measles virus persistent infection on AP-1 transcription factor binding in neuroblastoma cells., PMID:9237627
Immunopurification of polyclonal antibodies to recombinant proteins of the same gene family., PMID:8969818
Isolation and characterization of murine fra-1: induction mediated by CD40 and surface Ig is protein kinase C dependent., PMID:8892610
v-erbA oncogene induces invasiveness and anchorage-independent growth in cultured glial cells by mechanisms involving platelet-derived growth factor., PMID:8838867
12-O-tetradecanoylphorbol-13-acetate--induced levels of AP-1 proteins: a 46-kDa protein immunoprecipitated by anti-fra-1 and induced in promotion-resistant but not promotion-sensitive JB6 cells., PMID:1445622
For research use only. Not for human or drug use.
