Catalog No.
YHC28601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe549-His767
Predicted molecular weight
27.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07942
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin-1 subunit beta, Laminin-8 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-10 subunit beta, Laminin B1 chain, Laminin subunit beta-1, LAMB1, Laminin-12 subunit beta, laminin-1, laminin-111, EHS laminin, laminin-2, laminin-211, merosin, laminin-6, laminin-311, K-laminin, laminin-8, laminin-411, laminin-10, laminin-511, laminin-12, laminin-213
Hippocampal Extracellular Matrix Protein Laminin β1 Regulates Neuropathic Pain and Pain-Related Cognitive Impairment., PMID:40397355
Functional analysis of pathogenic variants in LAMB1-related leukoencephalopathy reveals genotype-phenotype correlations and suggests its role in glial cells., PMID:40237576
Lnc-DARVR/miR-365-1-5p/LAMB1 axis regulates rotavirus replication via the complement C3 pathway., PMID:40237496
Lamb1-mediated Wnt/β-catenin signaling pathway drives endothelial angiogenesis for fracture healing., PMID:40221061
Exome sequencing reveals low-frequency and rare variant contributions to multiple sclerosis susceptibility in Turkish families., PMID:40188234
The potential key genes within focal adhesion that regulate mesenchymal stem cells osteogenesis or adipogenesis in microgravity related disuse osteoporosis: an integrated analysis., PMID:40130165
Ethoxychelerythrine as a potential therapeutic strategy targets PI3K/AKT/mTOR induced mitochondrial apoptosis in the treatment of colorectal cancer., PMID:39994297
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment., PMID:39874810
Loss of Arhgap39 facilitates cell migration and invasion in murine hepatocellular cancer cells., PMID:39866228
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin., PMID:39522978
Laminin Beta 2 Is Localized at the Sites of Blood-Brain Barrier and Its Disruption Is Associated With Increased Vascular Permeability, Histochemical, and Transcriptomic Study., PMID:39340425
The prognostic value of bioinformatics analysis of ECM receptor signaling pathways and LAMB1 identification as a promising prognostic biomarker of lung adenocarcinoma., PMID:39312319
Proteomics and Bioinformatics Identify Drug-Resistant-Related Genes with Prognostic Potential in Cholangiocarcinoma., PMID:39199357
Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells., PMID:39106056
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
[Clinical and bioinformatics analysis of the relationship between LAMA3 DNA methylation expression and platinum resistance and prognosis in epithelial ovarian cancer]., PMID:38951081
Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis., PMID:38775886
Proteomic Identification of Small Extracellular Vesicle Proteins LAMB1 and Histone H4 for Prostate Cancer Diagnosis and Risk Stratification., PMID:38590132
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation., PMID:38582945
Simulating neuronal development: exploring potential mechanisms for central nervous system metastasis in acute lymphoblastic leukemia., PMID:38239636
Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma., PMID:38031074
A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)., PMID:37967346
Identification and validation of key genes associated with pathogenesis and prognosis of gastric cancer., PMID:37868053
Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila., PMID:37837732
Novel homozygous LAMB1 in-frame deletion in a pediatric patient with brain anomalies and cerebrovascular event., PMID:37466007
Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation., PMID:37205546
Screening and Bioinformatics Analyses of Key miRNAs Associated with Toll-like Receptor Activation in Gastric Cancer Cells., PMID:36984512
Focal adhesion signaling pathway involved in skin immune response of tongue sole Cynoglossus semilaevis to Vibrio vulnificus infection., PMID:36863497
Seven basement membrane-specific expressed genes are considered potential biomarkers for the diagnosis and treatment of diabetic nephropathy., PMID:36627452
Effects of the Dietary Inclusion of Allium mongolicum Regel Extract on Serum Index and Meat Quality in Small-Tailed Han Sheep., PMID:36611719
Substrate stiffness promotes dentinogenesis via LAMB1-FAK-MEK1/2 signaling axis., PMID:36519511
A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma., PMID:36494846
AZD6738 decreases intraocular pressure and inhibits fibrotic response in trabecular meshwork through CHK1/P53 pathway., PMID:36347274
Basigin is necessary for normal decidualization of human uterine stromal cells., PMID:36303457
Single-Cell Transcriptomics of Endothelial Cells in Upper and Lower Human Esophageal Squamous Cell Carcinoma., PMID:36290884
Laminin-111 mutant studies reveal a hierarchy within laminin-111 genes in their requirement for basal epithelial tissue folding., PMID:36244504
NLRP3 rs1539019 is significantly associated with chronic obstructive pulmonary disease in a Chinese Han population: a case-control study., PMID:36066157
Compound variants of FKTN, POMGNT1, and LAMB1 gene identified by prenatal whole-exome sequencing in three fetuses with congenital hydrocephalus., PMID:35843586
Adenoid cystic carcinoma in children and young adults: A clinicopathological study of 12 cases., PMID:35818778
RNA Helicase DDX24 Stabilizes LAMB1 to Promote Hepatocellular Carcinoma Progression., PMID:35763670
Peroxynitrous acid-modified extracellular matrix alters gene and protein expression in human coronary artery smooth muscle cells and induces a pro-inflammatory phenotype., PMID:35526806
Evaluation of JUN, FN1 and LAMB1 polymorphisms in pterygium in a Chinese Han population., PMID:35445627
Expression and prognostic analysis of BGN in head and neck squamous cell carcinoma., PMID:35358652
Excessive hydrogen sulfide causes lung and brain tissue damage by promoting PARP1/Bax and C9 and inhibiting LAMB1., PMID:35119561
Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells., PMID:34827207
A homozygous missense variant in laminin subunit beta 1 as candidate causal mutation of hemifacial microsomia in Romagnola cattle., PMID:34796979
Development and validation of genomic and epigenomic signatures associated with tumor immune microenvironment in hepatoblastoma., PMID:34711185
The Xiaogu San Attenuates Pain and Cartilage Damage in Rats with Monosodium Iodoacetate Induced Osteoarthritis., PMID:34629040
End-Truncated LAMB1 Causes a Hippocampal Memory Defect and a Leukoencephalopathy., PMID:34606115
Master Regulators of Epithelial-Mesenchymal Transition and WNT Signaling Pathways in Juvenile Nasopharyngeal Angiofibromas., PMID:34572445
For research use only. Not for human or drug use.
