Catalog No.
RHC13907
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05121
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1K02
Tumor microenvironment modulation by SERPINE1 increases radioimmunotherapy in murine model of gastric cancer., PMID:40355586
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice from FOLFOX-Induced Liver Injury., PMID:40246076
Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:40202938
Embryonic reprogramming of the tumor vasculature reveals targets for cancer therapy., PMID:40096611
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559
Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:39974095
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
In vitro neutralization of IL-6 receptor exacerbates damage to intestinal epithelial cells during Mycobacterium avium paratuberculosis infection., PMID:39170608
Plasma proteomic profiling reveals that SERPINE1 is a potential biomarker associated with coronary artery lesions in Kawasaki disease., PMID:39029232
Genetic Polymorphisms of GP1BA, PEAR1, and PAI-1 may be Associated with Serum sIgE and Blood Eosinophil Levels in Chinese Patients with Allergic Diseases., PMID:38299390
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies., PMID:37718518
Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases., PMID:37429356
Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells., PMID:37415190
Continuous Administration of Anti-VEGFA Antibody Upregulates PAI-1 Secretion from Ovarian Cancer Cells via miR-143-3p Downregulation., PMID:37327051
Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling., PMID:36810912
Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development., PMID:36440002
Diagnosis and treatment of acquired factor VIII deficiency: a case report and literature review., PMID:36281058
Complement system-related genes in stomach adenocarcinoma: Prognostic signature, immune landscape, and drug resistance., PMID:36159981
Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology., PMID:36129033
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1., PMID:36098461
Serum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction., PMID:34741085
CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1., PMID:34290311
Novel DNA methylation markers of PRRSV-specific antibodies and their intergenerational transmission from pregnant sows to piglets., PMID:34274485
Dysregulation of Pulmonary Responses in Severe COVID-19., PMID:34064104
A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?, PMID:33800359
Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484., PMID:33540702
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome., PMID:32826331
Evaluation of Osteogenic/Cementogenic Modulating Potential of PAI-1 Transfected Media for Stem Cells., PMID:32603295
Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1., PMID:32363188
Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells., PMID:32001531
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart., PMID:31723062
The prognostic and predictive significance of plasma type 1 plasminogen activator inhibitor and endoglin in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy., PMID:30880754
Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis., PMID:29858547
Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice., PMID:28981198
CLINICAL AND GENETIC PECULIARITIES OF VASCULAR MANIFESTATIONS OF ANTIPHOSPHOLIPID SYNDROME (CASE REPORT)., PMID:28726667
The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance., PMID:28574439
Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm., PMID:28385000
Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice., PMID:28270519
Polymorphism 4G/5G of the plasminogen activator inhibitor 1 gene as a risk factor for the development of allergic rhinitis symptoms in patients with asthma., PMID:28258374
Fibrinolysis inhibitors in plaque stability: a morphological association of PAI-1 and TAFI in advanced carotid plaque., PMID:28135035
FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma., PMID:28009608
Associations of serum anti-ganglioside antibodies and inflammatory markers in diabetic peripheral neuropathy., PMID:27242125
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab., PMID:27001121
Increased Umbilical Cord PAI-1 Levels in Placental Insufficiency Are Associated with Fetal Hypoxia and Angiogenesis., PMID:26903689
Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence., PMID:26802937
[[Gender Differences in Tissue Cascade of Activation of Plasminogen and PAI-1 in Esophageal Squamous Cell Carcinoma].]., PMID:28614640
Testosterone Therapy Can Interact With Thrombophilia, Leading to Osteonecrosis., PMID:26652327
Plasminogen Activation System in Rectal Adenocarcinoma., PMID:26504024
[The role of inherited thrombophilia and undifferentiated connective tissue dysplasia syndrome in the pathogenesis of female infertility: A clinical and morphological study]., PMID:26485774
For research use only. Not for human or drug use.
