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Anti-ATG12 Antibody (R1G01)

Catalog #:   RHB44602 Specific References (35) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, IHC, IP, WB
Accession: O94817
Overview

Catalog No.

RHB44602

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

Autophagy-related protein 12, APG12-like, Ubiquitin-like protein ATG12, APG12L, APG12, ATG12

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O94817

Applications

FCM, IF, IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1G01

Data Image
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of Apg12(Atg12) expression in 293 cell lysate.
References

MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest., PMID:39586385

Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826

Upregulation of ATG9b by propranolol promotes autophagic cell death of hepatic stellate cells to improve liver fibrosis., PMID:37970991

Evaluation of the mTORC activity in the presence of Toxoplasma gondii and azathioprine in human monocyte cell line., PMID:36941573

Effects of in vitro vitamin D treatment on function of T cells and autophagy mechanisms in high-fat diet-induced obese mice., PMID:34858547

Positively Correlated CD47 Activation and Autophagy in Umbilical Cord Blood-Derived Mesenchymal Stem Cells during Senescence., PMID:33936211

Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells., PMID:33801244

The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore., PMID:33783314

Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes., PMID:33730050

Scanning Electron-Assisted Dielectric Microscopy Reveals Autophagosome Formation by LC3 and ATG12 in Cultured Mammalian Cells., PMID:33673233

The Role of Autophagy-Mediated Dengue Virus Antibody-Dependent Enhancement Infection of THP-1 Cells., PMID:33202415

Vitamin D - A host directed autophagy mediated therapy for tuberculosis., PMID:33039674

An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells., PMID:32897127

Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice., PMID:32677505

Alpha-neoendorphin can reduce UVB-induced skin photoaging by activating cellular autophagy., PMID:32526201

Endometrial autophagy is essential for embryo implantation during early pregnancy., PMID:32072231

Decreased Expression of MicroRNA-107 in B Lymphocytes of Patients with Antibody-Mediated Renal Allograft Rejection., PMID:30333363

ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744

Effect of follicle cell autophagy on gonadal development of triploid female rainbow trout (Oncorhynchus mykiss)., PMID:29086110

Crosstalk Influence between P38MAPK and Autophagy on Mitochondria-Mediated Apoptosis Induced by Anti-Fas Antibody/Actinomycin D in Human Hepatoma Bel-7402 Cells., PMID:29039784

Tranexamic acid inhibits melanogenesis by activating the autophagy system in cultured melanoma cells., PMID:28669590

[Effect of Xinfeng Capsule on AS Patients and Their Serum Immunoglobulin Subtypes and Peripheral Lymphocyte Autophagy]., PMID:27236888

A Prospective Pharmacogenomic Study of Crohn's Disease Patients during Routine Therapy with Anti-TNF-α Drug Adalimumab: Contribution of ATG5, NFKB1, and CRP Genes to Pharmacodynamic Variability., PMID:27096233

Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy., PMID:26923481

Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production., PMID:25151985

Post-transcriptional regulation of autophagy in C2C12 myotubes following starvation and nutrient restoration., PMID:25043686

Electroconvulsive seizures enhance autophagy signaling in rat hippocampus., PMID:24316174

Role of the EphB2 receptor in autophagy, apoptosis and invasion in human breast cancer cells., PMID:24211352

The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer., PMID:23965851

Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment., PMID:23307622

IL-6 inhibits IFN-γ induced autophagy in Mycobacterium tuberculosis H37Rv infected macrophages., PMID:22426116

Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease., PMID:20102518

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production., PMID:18849965

Autophagy during proliferation and encystation in the protozoan parasite Entamoeba invadens., PMID:17923513

NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia., PMID:17213804

Datasheet

Document Download

Anti-ATG12 Antibody (R1G01).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-ATG12 Antibody (R1G01) [RHB44602]
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