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Anti-MACROH2A1 Antibody (R1F22)

Catalog #:   RHB17201 Specific References (15) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, WB
Accession: O75367
Overview

Catalog No.

RHB17201

Species reactivity

Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, WB: 1:500-1:1000

Target

Histone macroH2A1, mH2A1, H2A/y, MACROH2A1, Medulloblastoma antigen MU-MB-50.205, Core histone macro-H2A.1, H2AFY, Histone H2A.y

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75367

Applications

IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1F22

Data Image
  • Immunofluorescence
    Immunocytochemistry analysis of macroH2A.1(green) in Hela using macroH2A.1 antibody,and DAPI(blue)
  • Western blot
    Western blot analysis of macroH2A.1 in rat Brain, C6, 3T3 lysates using Macro H2A.1 antibody.
References

Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1., PMID:39545415

Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma., PMID:39255035

Integrated spatial genomics reveals global architecture of single nuclei., PMID:33505024

The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate., PMID:28564596

MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis., PMID:25526730

Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domains., PMID:23118866

X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2., PMID:21738686

The histone H2A variant macroH2A1 does not localize to the centrosome., PMID:21364955

Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome., PMID:18936163

Epigenetic processes in a tetraploid mammal., PMID:18758856

A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis., PMID:18227505

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist., PMID:12356914

Histone macroH2A1 is concentrated in the inactive X chromosome of female preimplantation mouse embryos., PMID:10804171

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals., PMID:9634239

Developmental and tissue expression patterns of histone macroH2A1 subtypes., PMID:9138085

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-MACROH2A1 Antibody (R1F22) [RHB17201]
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