Catalog No.
RHA27101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
PGES, PTGES, Prostaglandin E synthase, MPGES1, Microsomal prostaglandin E synthase 1, MGST1-L1, PIG12, p53-induced gene 12 protein, Glutathione transferase PTGES, MGST1L1, MPGES-1, Glutathione peroxidase PTGES, Microsomal glutathione S-transferase 1-like 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O14684
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D24
Structure Bioinformatics of Six Human Integral Transmembrane Enzymes and their AlphaFold3 Predicted Water-Soluble QTY Analogs: Insights into FACE1 and STEA4 Binding Mechanisms., PMID:39966220
The Role of mPGES-1 in Promoting Granulation Tissue Angiogenesis Through Regulatory T-cell Accumulation., PMID:36099134
Inhibition of mPGES-1 attenuates efficient resolution of acute inflammation by enhancing CX3CL1 expression., PMID:33542207
CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitors., PMID:30879343
Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells., PMID:29777205
Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma., PMID:29149426
PGE2 /EP4 Signaling Controls the Transfer of the Mammary Stem Cell State by Lipid Rafts in Extracellular Vesicles., PMID:27506158
Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury., PMID:27102561
Preventive effects of dietary hydroxytyrosol acetate, an extra virgin olive oil polyphenol in murine collagen-induced arthritis., PMID:26382723
Paracrine in vivo inhibitory effects of adipose tissue-derived mesenchymal stromal cells in the early stages of the acute inflammatory response., PMID:26276006
Expression of Prostaglandin E2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients., PMID:26225917
Canine placental prostaglandin E2 synthase: expression, localization, and biological functions in providing substrates for prepartum PGF2alpha synthesis., PMID:25297547
Distribution of microsomal prostaglandin E synthase-1 in the mouse brain., PMID:24668417
Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells., PMID:24127557
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice., PMID:24055573
Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results., PMID:23525414
Cancer-induced anorexia in tumor-bearing mice is dependent on cyclooxygenase-1., PMID:23305935
Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results., PMID:22588264
Glucosamine sulfate reduces prostaglandin E(2) production in osteoarthritic chondrocytes through inhibition of microsomal PGE synthase-1., PMID:22089456
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis., PMID:21266028
Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes., PMID:20144213
Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients., PMID:19412621
The terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas., PMID:19347995
Detection of fascin and CCR-7 positive mature dendritic cells in oral lichen planus., PMID:19243493
Elevated microsomal prostaglandin-E synthase-1 in Alzheimer's disease., PMID:18631945
Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis., PMID:18094001
Expression of microsomal prostaglandin E synthase-1 in human hepatocelluar carcinoma., PMID:17696939
Pulmonary and cardiorenal cyclooxygenase-1 (COX-1), -2 (COX-2), and microsomal prostaglandin E synthase-1 (mPGES-1) and -2 (mPGES-2) expression in a hypertension model., PMID:17641732
The expression pattern of prostaglandin E synthase and EP receptor isoforms in normal mouse skin and preinvasive skin neoplasms., PMID:17437488
Interleukin-6 is a candidate molecule that transmits inflammatory information to the CNS., PMID:17303338
Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1., PMID:16574649
Effects of antirheumatic treatments on the prostaglandin E2 biosynthetic pathway., PMID:16255020
Despite transcriptional and functional coordination, cyclooxygenase-2 and microsomal prostaglandin E synthase-1 largely reside in distinct lipid microdomains in WISH epithelial cells., PMID:15983118
Prostaglandin E synthase in the pathophysiology of arthritis., PMID:15910650
Species-specific expression of microsomal prostaglandin E synthase-1 and cyclooxygenases in male monkey reproductive organs., PMID:15301794
Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium., PMID:15188353
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1., PMID:15140897
Immunohistochemical localization of microsomal PGE synthase-1 and cyclooxygenases in male mouse reproductive organs., PMID:12021206
Biochemical characterization of mouse microsomal prostaglandin E synthase-1 and its colocalization with cyclooxygenase-2 in peritoneal macrophages., PMID:11795891