Catalog No.
RHA16402
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
C-C motif chemokine 21, SCYA21, Small-inducible cytokine A21, CCL21, Beta-chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00585
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D02
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma., PMID:40393449
Initiation of primary T cell-B cell interactions and extrafollicular antibody responses in an organized microphysiological model of the human lymph node., PMID:39868310
High-dose radiation-induced immunogenic cell death of bladder cancer cells leads to dendritic cell activation., PMID:39231199
Blockade of CD93 in pleural mesothelial cells fuels anti-lung tumor immune responses., PMID:38250037
A mechanistic marker-based screening tool to predict clinical immunogenicity of biologics., PMID:38066254
The role of blood podoplanin in patients with viral myocarditis., PMID:37669599
On-Chip Discovery of Allergens from the Exudate of Large Yellow Croaker (Larimichthys Crocea) Muscle Food by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry., PMID:37647599
A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy., PMID:37446007
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma., PMID:37379367
CCL21/CCR7 axis as a therapeutic target for autoimmune diseases., PMID:37331295
Atlas of the anatomical localization of atypical chemokine receptors in healthy mice., PMID:37159457
Tumor immune microenvironment of cutaneous angiosarcoma with cancer testis antigens and the formation of tertiary lymphoid structures., PMID:37081973
Association between the expression of toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity., PMID:36589720
Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension., PMID:36211384
Development of a human antibody that exhibits antagonistic activity toward CC chemokine receptor 7., PMID:35967907
Nociception-Dependent CCL21 Induces Dorsal Root Ganglia Axonal Growth via CCR7-ERK Activation., PMID:35911704
Considerations for Novel COVID-19 Mucosal Vaccine Development., PMID:35893822
CCL21 contributes to Th17 cell migration in neuroinflammation in obese mice following lead exposure., PMID:35752368
Trichinella spiralis nurse cell formation is regulated via CCR7+ dendritic cells., PMID:35689825
Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure., PMID:35689481
Nurselike cells sequester B cells in disorganized lymph nodes in chronic lymphocytic leukemia via alternative production of CCL21., PMID:35679464
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift., PMID:35513371
Drainage of senescent astrocytes from brain via meningeal lymphatic routes., PMID:35427759
A subpopulation of green turtle suprabasal epidermal cells are Langerin+ and migrate under in vitro stimulation of the chemokine CCL21., PMID:35098399
A formulated poly (I:C)/CCL21 as an effective mucosal adjuvant for gamma-irradiated influenza vaccine., PMID:34627297
The Entry and Egress of Monocytes in Atherosclerosis: A Biochemical and Biomechanical Driven Process., PMID:34345249
A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease., PMID:34197491
CCR7-CCL21 axis promotes the cervical lymph node metastasis of tongue squamous cell carcinoma by up-regulating MUC1., PMID:33966967
Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes., PMID:33912981
Novel Human Tenascin-C Function-Blocking Camel Single Domain Nanobodies., PMID:33790905
Evaluation of CCL21 role in post-knee injury inflammation and early cartilage degeneration., PMID:33651836
Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis., PMID:40270643
Inhibition of fibroblast IL-6 production by ACKR4 deletion alleviates cardiac remodeling after myocardial infarction., PMID:33610913
Infrared radiation from cage bedding moderates rat inflammatory and autoimmune responses in collagen-induced arthritis., PMID:33536461
Remodeling of the Lymph Node High Endothelial Venules Reflects Tumor Invasiveness in Breast Cancer and is Associated with Dysregulation of Perivascular Stromal Cells., PMID:33430113
T cell-depleted cultured pediatric thymus tissue as a model for some aspects of human age-related thymus involution., PMID:33420705
Tertiary lymphoid organs are associated with the progression of kidney damage and regulated by interleukin-17A., PMID:33391465
A review of vaccine effects on women in light of the COVID-19 pandemic., PMID:33218394
Presence of Tertiary Lymphoid Organ in Nasal Inverted Papilloma Is Correlated with Eosinophil Infiltration and Local Immunoglobulin Production., PMID:33207352
Cerebrospinal Fluid IgM Levels in Association With Inflammatory Pathways in Multiple Sclerosis Patients., PMID:33192314
Immune Checkpoint Blockade Enhances Immune Activity of Therapeutic Lung Cancer Vaccine., PMID:33167311
Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis., PMID:33061527
Densities of decidual high endothelial venules correlate with T-cell influx in healthy pregnancies and idiopathic recurrent pregnancy losses., PMID:32940686
Impact of Local Alloimmunity and Recipient Cells in Transplant Arteriosclerosis., PMID:32689904
PD-1 Immune Checkpoint Blockade Promotes Therapeutic Cancer Vaccine to Eradicate Lung Cancer., PMID:32570793
Pro-lymphangiogenic VEGFR-3 signaling modulates memory T cell responses in allergic airway inflammation., PMID:32518367
Anti-HER2 induced myeloid cell alterations correspond with increasing vascular maturation in a murine model of HER2+ breast cancer., PMID:32345237
CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients., PMID:32330476
CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells., PMID:32210425
For research use only. Not for human or drug use.
