Anti-APBB1 Antibody (R1C67)

Catalog No.

RHA05502

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

APBB1, Amyloid-beta A4 precursor protein-binding family B member 1, Protein Fe65, RIR, FE65

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O00213

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1C67

An autoantibody profile identified by human genome-wide protein arrays in rheumatoid arthritis., PMID:39132510

Visualization and quantification of APP intracellular domain-mediated nuclear signaling by bimolecular fluorescence complementation., PMID:24086696

Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65., PMID:22352297

Interferon-inducible factor 16 is a novel modulator of glucocorticoid action., PMID:20086048

Regulation Fe65 localization to the nucleus by SGK1 phosphorylation of its Ser566 residue., PMID:18304449

Fe65 interacts with P2X2 subunits at excitatory synapses and modulates receptor function., PMID:16330549

A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein., PMID:16103124

Interaction of Tau with Fe65 links tau to APP., PMID:15686969

Isoform-specific knockout of FE65 leads to impaired learning and memory., PMID:14689444

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins., PMID:12779321

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK., PMID:11517249

Characterization of an apoptosis inhibitory domain at the C-termini of FE65-like protein., PMID:11027557

hFE65L influences amyloid precursor protein maturation and secretion., PMID:10461887

DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter., PMID:9359867

Document Download

Anti-APBB1 Antibody (R1C67).pdf