Catalog No.
YHC10102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp2-Ala61
Predicted molecular weight
21.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04731
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MT1S, Metallothionein-IA, MT-IA, Metallothionein-1A, MT-1A, MT1A
The Potential Dual Roles of Metallothionein-1/-2 in Diabetic Osteoarthritis., PMID:40518852
Prenatal Constant Light Exposure Induces Behavioral Deficits in Male and Female Rat Offspring: Effects of Prenatal Melatonin Treatment., PMID:39940805
Metallothionein-1A (MT1A) Gene Variability May Play a Role in Female Frailty: A Preliminary Study., PMID:39858562
Identification of genes contributing to attenuation of rat model of galactose-induced cataract by pyruvate., PMID:39219252
Cadmium exposure and its association with oxidative stress, MT1A methylation, and idiopathic male infertility in Egypt: A case-control study., PMID:39142552
Development of prognostic model incorporating a ferroptosis/cuproptosis-related signature and mutational landscape analysis in muscle-invasive bladder cancer., PMID:39107713
Deciphering the role of zinc homeostasis in the tumor microenvironment and prognosis of prostate cancer., PMID:38833013
Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview., PMID:38535959
ESI-MS analysis of Cu(I) binding to apo and Zn7 human metallothionein 1A, 2, and 3 identifies the formation of a similar series of metallated species with no individual isoform optimization for Cu(I)., PMID:38503570
scRNA-seq analysis discovered suppression of immunomodulatory dependent inflammatory response in PMBCs exposed to silver nanoparticles., PMID:38494495
Influence of copper source and dietary inclusion level on growth performance of weaned pigs and expression of trace element related genes in the small intestine., PMID:38492538
Human apo-metallothionein 1a is not a random coil: Evidence from guanidinium chloride, high temperature, and acidic pH unfolding studies., PMID:38490456
Gene Expression Analysis of a Topical Serum Comprised of Plant-based Adaptogens Developed to Support Homeostasis and Skin Quality., PMID:38444426
Bi(III) Binding Stoichiometry and Domain-Specificity Differences Between Apo and Zn(II)-bound Human Metallothionein 1a., PMID:38356034
Protective Effect of the Novel Melatonin Analogue Containing Donepezil Fragment on Memory Impairment via MT/ERK/CREB Signaling in the Hippocampus in a Rat Model of Pinealectomy and Subsequent Aβ1-42 Infusion., PMID:38339146
Epigenomic analysis of the myometrium during late implantation revealed regulatory elements in genes related to the cellular zinc homeostasis pathway in pigs., PMID:38128703
Up-Regulated Expression of ICAM1, MT1A, PTGS2, LCE3D, PPARD, and GM-CSF2 Following Solar Skincare Protection and Repair Strategies in a 3-Dimensional Reconstructed Human Skin Model., PMID:37850108
Melatonin protects HT-22 cells against palmitic acid-induced glucolipid metabolic dysfunction and cell injuries: Involved in the regulation of synaptic plasticity and circadian rhythms., PMID:37804870
Assessing organism differences in mixed metal sensitivity., PMID:37751843
Development and Validation of the Promising PPAR Signaling Pathway-Based Prognostic Prediction Model in Uterine Cervical Cancer., PMID:37292383
Integrative pan-cancer analysis of cuproplasia-associated genes for the genomic and clinical characterization of 33 tumors., PMID:37027423
An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies., PMID:36981043
Melatonin Supports the Survival of Cholinergic Neurons in Organotypic Brain Slices of the Basal Nucleus of Meynert., PMID:36724742
The Difference in Zinc Concentrations Required for Induction among Metallothionein Isoforms Can Be Explained by the Different MTF1 Affinities to MREs in Its Promoter., PMID:36613726
Protective effect of melatonin on learning and memory impairment and hippocampal dysfunction in rats induced by high-fructose corn syrup., PMID:36594054
63Cu(I) binding to human kidney 68Zn7-βα MT1A: determination of Cu(I)-thiolate cluster domain specificity from ESI-MS and room temperature phosphorescence spectroscopy., PMID:36583699
Gene Expression Profiling as a New Real-Time Assay in Human Biomonitoring of Waste-to-Energy Plant Workers., PMID:36394794
Intake of mother's milk by very-low-birth-weight infants and variation in DNA methylation of genes involved in neurodevelopment at 5.5 years of age., PMID:35977396
Metallothioneins in Dental Implant Treatment Failure and Periodontitis in Patients with Down's Syndrome: Validation of Results., PMID:35741790
Metals and Metallothionein Expression in Relation to Progression of Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka., PMID:35735634
Genetic Variations in Metallothionein Genes and Susceptibility to Hypertensive Disorders of Pregnancy: A Case-Control Study., PMID:35734434
Targeted Analysis of Tears Revealed Specific Altered Metal Homeostasis in Age-Related Macular Degeneration., PMID:35426907
Oxidative Stress in Dairy Cows: Insights into the Mechanistic Mode of Actions and Mitigating Strategies., PMID:34943022
Integrative analysis of immune-related multi-omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma., PMID:34894177
Zinc Inhibits Cadherin 1 Expression Induced by 1α,25-Dihydroxyvitamin D3 in Colon Cancer Cells., PMID:34732414
Integrative Analysis of Metallothioneins Identifies MT1H as Candidate Prognostic Biomarker in Hepatocellular Carcinoma., PMID:34676244
Role of MT1A Polymorphism and Environmental Mercury Exposure on the Montreal Cognitive Assessment (MoCA)., PMID:34326641
Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease., PMID:34297416
Content of total aflatoxin, lead, and cadmium in the bovine meat and edible offal: study of their human dietary intake, health risk assessment, and molecular biomarkers., PMID:34170471
Importance of Genetic Polymorphisms in MT1 and MT2 Genes in Metals Homeostasis and Their Relationship with the Risk of Acute Pancreatitis Occurrence in Smokers-Preliminary Findings., PMID:34072023
Effects of Androgen Receptor Inhibition on Kanamycin-Induced Hearing Loss in Rats., PMID:34070066
The association between estimated glomerular filtration rate and cadmium exposure: An 8-year follow-up study., PMID:34052740
Time dependent impact of copper oxide nanomaterials on the expression of genes associated with oxidative stress, metal binding, inflammation and mucus secretion in single and co-culture intestinal in vitro models., PMID:33839236
The influence of dietary energy and zinc source and concentration on performance, trace mineral status, and gene expression of beef steers., PMID:33409464
Biomechanical Forces Regulate Gene Transcription During Stretch-Mediated Growth of Mammalian Neurons., PMID:33408609
Revisiting the metallothionein genes polymorphisms and the risk of oral squamous cell carcinoma in a Brazilian population., PMID:33340085
Induction of metallothionein isoforms in cultured bovine aortic endothelial cells exposed to cadmium., PMID:33268680
The pathways and domain specificity of Cu(I) binding to human metallothionein 1A., PMID:33225329
Corneal tissue induces transcription of metallothioneins in monocyte-derived human macrophages., PMID:33137607
Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma., PMID:33122816
For research use only. Not for human or drug use.
