Catalog No.
RHD74301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
ARNT, HIF-1beta, HIF1B, HIF1BETA, TANGO, bHLHe2, HIF 1 beta
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27540
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1C41
A PAS-targeting hERG1 activator reduces arrhythmic events in Jervell and Lange-Nielsen syndrome patient-derived hiPSC-CMs., PMID:39786967
IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation., PMID:39707175
Single-cell insights: pioneering an integrated atlas of chromatin accessibility and transcriptomic landscapes in diabetic cardiomyopathy., PMID:38664790
Association of the AhR, ARNT, and AhRR gene polymorphisms and cord blood AhR levels with elevated cord blood IgE susceptibility in Taiwan mother-infant pairs: a nested case-control study., PMID:38590026
Beyond Conventional Therapies: Molecular Dynamics of Alzheimer's Treatment through CLOCK/BMAL1 Interactions., PMID:38509675
Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells., PMID:38000295
Screening of lipid-A related genes and development of low-endotoxicity live-attenuated Salmonella gallinarum by arnT deletion that elicits immune responses and protection against fowl typhoid in chickens., PMID:37044268
CYP1A1 Is a Useful Diagnostic Marker for Angiofibroma of Soft Tissue., PMID:36876749
Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway., PMID:36871457
Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating., PMID:34716268
Effects of oral administration of Spirulina platensis and probiotics on serum immunity indexes, colonic immune factors, fecal odor, and fecal flora in mice., PMID:34289202
Biochemical properties of human full-length aryl hydrocarbon receptor (AhR)., PMID:32289173
Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma., PMID:29672862
The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction., PMID:28067314
Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator., PMID:27853106
Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain., PMID:27516548
Development and characterization of monoclonal antibodies against human aryl hydrocarbon receptor., PMID:26899655
Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion., PMID:26861754
Influence of allelic Variations of hypoxia-related and DNA repair genes on patient outcome and toxicity in head and neck cancer treated with radiotherapy plus cetuximab., PMID:26245169
Improvement of risk assessment in systemic light-chain amyloidosis using human placental growth factor., PMID:25331161
Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressor., PMID:25265996
Brain and muscle Arnt-like 1 promotes skeletal muscle regeneration through satellite cell expansion., PMID:25218946
Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs., PMID:24709292
The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation., PMID:24519526
Chronic lymphocytic leukemia in a child: a challenging diagnosis in pediatric oncology practice., PMID:24249660
AGR2 expression is regulated by HIF-1 and contributes to growth and angiogenesis of glioblastoma., PMID:23712868
4S polycyclic aromatic hydrocarbon receptor (glycine N-methyltransferase) and the aryl hydrocarbon receptor nuclear translocator (hypoxia inducible factor-1β) interaction in Chinese hamster ovary and rat hepatoma cells: 4S PAH-R/ARNT hetero-oligomers?, PMID:21445860
Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocators in human adenoid tissue., PMID:21273015
CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma., PMID:20851862
The intravenous anesthetic propofol inhibits lipopolysaccharide-induced hypoxia-inducible factor 1 activation and suppresses the glucose metabolism in macrophages., PMID:20039079
[Construction of the dioxin bioassay method based on the clonal expressed aryl hydrocarbon receptor system]., PMID:20021851
The intravenous anesthetics barbiturates inhibit hypoxia-inducible factor 1 activation., PMID:19595685
Cytolytic T-cell response to the PASD1 cancer testis antigen in patients with diffuse large B-cell lymphoma., PMID:19552722
High prevalence of amyloid in 150 surgically removed heart valves--a comparison of histological and clinical data reveals a correlation to atheroinflammatory conditions., PMID:19502085
Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing., PMID:18591338
[Preliminary study of PRL-3 gene promoter binding sites of Snail in SW480 cells]., PMID:17545014
[Effects of benzo(a)pyrene on the expression of gamma-glutamate-cysteine ligase: a primary study with rat alveolar epithelial cells]., PMID:17288842
MOP3, a component of the molecular clock, regulates the development of B cells., PMID:16925591
Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: the central role of proinflammatory cytokines., PMID:16820944
The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhythms, quiescence, and expression of clock genes in murine hematopoietic stem and progenitor cells., PMID:16556773
Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells., PMID:16304044
Two doses of parenterally administered split influenza virus vaccine elicited high serum IgG concentrations which effectively limited viral shedding upon challenge in mice., PMID:16253121
Purification and characterization of the L-Ara4N transferase protein ArnT from Salmonella typhimurium., PMID:16226890
Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice., PMID:16092921
Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells., PMID:15635607
Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteins., PMID:15596729
Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation., PMID:15199114
Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators., PMID:15184363
Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose., PMID:15148392
Aryl-hydrocarbon receptor-dependent pathway and toxic effects of TCDD in humans: a population-based study in Seveso, Italy., PMID:15093275
For research use only. Not for human or drug use.
