Anti-CASP2 Antibody (R1C17)

Catalog No.

RME36001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

Caspase-2, Caspase 2, Caspase2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, CASP2, ICH1, NEDD2, Caspase 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29594

Applications

FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4 ℃ short term (1-2 weeks). Store at -20 ℃ 12 months. Store at -80 ℃ long term.

Clone ID

R1C17

Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2., PMID:30718480

Psoriasis Treatment Changes the Expression Profile of Selected Caspases and their Regulatory MicroRNAs., PMID:30308514

Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling., PMID:24727569

Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells., PMID:23540413

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression., PMID:19217671

Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade., PMID:11156409

Document Download

Anti-CASP2 Antibody (R1C17).pdf