Catalog No.
RHD67301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P25490
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1A72
Hydroxychloroquine cures autoimmune myocarditis by inhibiting the innate immune system via the C-X-C motif chemokine ligand 16 and C-X-C motif receptor 6 axis between macrophages and T cells., PMID:40222951
YY1 as a mediator to enhance the resistance of KRAS mutant colorectal cancer cells to cetuximab., PMID:39959936
The Role of YY1 in the Regulation of LAG-3 Expression in CD8 T Cells and Immune Evasion in Cancer: Therapeutic Implications., PMID:39796650
Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development., PMID:39627609
Metabolic determinants of germinal center B cell formation and responses., PMID:39060389
YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment., PMID:38990722
Cross-Talks between Raf Kinase Inhibitor Protein and Programmed Cell Death Ligand 1 Expressions in Cancer: Role in Immune Evasion and Therapeutic Implications., PMID:38786085
IL1R2 Blockade Alleviates Immunosuppression and Potentiates Anti-PD-1 Efficacy in Triple-Negative Breast Cancer., PMID:38657120
Regulation of PD-L1 Expression by YY1 in Cancer: Therapeutic Efficacy of Targeting YY1., PMID:38539569
SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis., PMID:37994046
Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation., PMID:37702072
Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression., PMID:37408047
Disruption of YY1-EZH2 Interaction Using Synthetic Peptides Inhibits Breast Cancer Development., PMID:34065631
The dystonia gene THAP1 controls DNA double-strand break repair choice., PMID:33857404
Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727
Vitamin D3-Induced Promotor Dissociation of PU.1 and YY1 Results in FcεRI Reduction on Dendritic Cells in Atopic Dermatitis., PMID:33443066
YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain., PMID:33300076
The Double-Faced Role of Nitric Oxide and Reactive Oxygen Species in Solid Tumors., PMID:32365852
IL-8 is involved in radiation therapy resistance of esophageal squamous cell carcinoma via regulation of PCNA., PMID:31629712
The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF., PMID:31285261
YY1 regulates cancer cell immune resistance by modulating PD-L1 expression., PMID:31005030
YY1 binds to the E3' enhancer and inhibits the expression of the immunoglobulin κ gene via epigenetic modifications., PMID:30098214
YY1 and HDAC9c transcriptionally regulate p38-mediated mesenchymal stem cell differentiation into osteoblasts., PMID:29637005
Sequential Enhancer Sequestration Dysregulates Recombination Center Formation at the IgH Locus., PMID:29576529
Aurora A Phosphorylation of YY1 during Mitosis Inactivates its DNA Binding Activity., PMID:28855673
YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction., PMID:28575647
Chromatin reader ZMYND8 is a key target of all trans retinoic acid-mediated inhibition of cancer cell proliferation., PMID:28232094
The Forgotten YY2 in Reported YY1 Expression Levels in Human Cancers., PMID:29604937
YY1 Is Required for Germinal Center B Cell Development., PMID:27167731
The YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface., PMID:27071480
Overexpression of YY1 increases the protein production in mammalian cells., PMID:26686315
Downregulation of the sodium channel Nav1.6 by potential transcriptomic deregulation may explain sensory deficits in critical illness neuropathy., PMID:26562765
Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci., PMID:26477366
A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation., PMID:26302788
An endogenous 'non-specific' protein detected by a His-tag antibody is human transcription regulator YY1., PMID:26217706
Yin Yang 1 contributes to gastric carcinogenesis and its nuclear expression correlates with shorter survival in patients with early stage gastric adenocarcinoma., PMID:24674326
Control of antigen receptor diversity through spatial regulation of V(D)J recombination., PMID:24584058
Function of YY1 in Long-Distance DNA Interactions., PMID:24575094
Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire., PMID:23973221
IL-4 polymorphisms, HRCT score and lung tissue markers in idiopathic pulmonary fibrosis., PMID:23911740
Androgen response element of the glycine N-methyltransferase gene is located in the coding region of its first exon., PMID:23883094
YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus., PMID:23531880
Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression., PMID:23416188
Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation., PMID:23248301
Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells., PMID:23027941
YY1-binding sites provide central switch functions in the PARP-1 gene expression network., PMID:22937159
Interaction of the transcription start site core region and transcription factor YY1 determine ascorbate transporter SVCT2 exon 1a promoter activity., PMID:22532872
YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels., PMID:22290437
Galiximab signals B-NHL cells and inhibits the activities of NF-κB-induced YY1- and snail-resistant factors: mechanism of sensitization to apoptosis by chemoimmunotherapeutic drugs., PMID:22267549
Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus., PMID:21982154
For research use only. Not for human or drug use.
