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Anti-YY1 Antibody (R1A72)

Catalog #:   RHD67301 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, IP, WB
Accession: P25490
Overview

Catalog No.

RHD67301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25490

Applications

IF, IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4 ℃ short term (1-2 weeks). Store at -20 ℃ 12 months. Store at -80 ℃ long term.

Clone ID

R1A72

Data Image
  • Immunofluorescence
    Immunofluorescent analysis of Hela cells, using YY1 Antibody.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human bladder using YY1 Antibody.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of YY1 expression in (1) HeLa cell lysate; (2) Daudi cell lysate.
  • Western blot
    Western blot analysis of YY1 expression in (1) HeLa cell lysate; (2) Daudi cell lysate.
References

Hydroxychloroquine cures autoimmune myocarditis by inhibiting the innate immune system via the C-X-C motif chemokine ligand 16 and C-X-C motif receptor 6 axis between macrophages and T cells., PMID:40222951

YY1 as a mediator to enhance the resistance of KRAS mutant colorectal cancer cells to cetuximab., PMID:39959936

The Role of YY1 in the Regulation of LAG-3 Expression in CD8 T Cells and Immune Evasion in Cancer: Therapeutic Implications., PMID:39796650

Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development., PMID:39627609

Metabolic determinants of germinal center B cell formation and responses., PMID:39060389

YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment., PMID:38990722

Cross-Talks between Raf Kinase Inhibitor Protein and Programmed Cell Death Ligand 1 Expressions in Cancer: Role in Immune Evasion and Therapeutic Implications., PMID:38786085

IL1R2 Blockade Alleviates Immunosuppression and Potentiates Anti-PD-1 Efficacy in Triple-Negative Breast Cancer., PMID:38657120

Regulation of PD-L1 Expression by YY1 in Cancer: Therapeutic Efficacy of Targeting YY1., PMID:38539569

SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis., PMID:37994046

Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation., PMID:37702072

Isorhamnetin and anti-PD-L1 antibody dual-functional mesoporous silica nanoparticles improve tumor immune microenvironment and inhibit YY1-mediated tumor progression., PMID:37408047

Disruption of YY1-EZH2 Interaction Using Synthetic Peptides Inhibits Breast Cancer Development., PMID:34065631

The dystonia gene THAP1 controls DNA double-strand break repair choice., PMID:33857404

Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727

Vitamin D3-Induced Promotor Dissociation of PU.1 and YY1 Results in FcεRI Reduction on Dendritic Cells in Atopic Dermatitis., PMID:33443066

YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain., PMID:33300076

The Double-Faced Role of Nitric Oxide and Reactive Oxygen Species in Solid Tumors., PMID:32365852

IL-8 is involved in radiation therapy resistance of esophageal squamous cell carcinoma via regulation of PCNA., PMID:31629712

The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF., PMID:31285261

YY1 regulates cancer cell immune resistance by modulating PD-L1 expression., PMID:31005030

YY1 binds to the E3' enhancer and inhibits the expression of the immunoglobulin κ gene via epigenetic modifications., PMID:30098214

YY1 and HDAC9c transcriptionally regulate p38-mediated mesenchymal stem cell differentiation into osteoblasts., PMID:29637005

Sequential Enhancer Sequestration Dysregulates Recombination Center Formation at the IgH Locus., PMID:29576529

Aurora A Phosphorylation of YY1 during Mitosis Inactivates its DNA Binding Activity., PMID:28855673

YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction., PMID:28575647

Chromatin reader ZMYND8 is a key target of all trans retinoic acid-mediated inhibition of cancer cell proliferation., PMID:28232094

The Forgotten YY2 in Reported YY1 Expression Levels in Human Cancers., PMID:29604937

YY1 Is Required for Germinal Center B Cell Development., PMID:27167731

The YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface., PMID:27071480

Overexpression of YY1 increases the protein production in mammalian cells., PMID:26686315

Downregulation of the sodium channel Nav1.6 by potential transcriptomic deregulation may explain sensory deficits in critical illness neuropathy., PMID:26562765

Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci., PMID:26477366

A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation., PMID:26302788

An endogenous 'non-specific' protein detected by a His-tag antibody is human transcription regulator YY1., PMID:26217706

Yin Yang 1 contributes to gastric carcinogenesis and its nuclear expression correlates with shorter survival in patients with early stage gastric adenocarcinoma., PMID:24674326

Control of antigen receptor diversity through spatial regulation of V(D)J recombination., PMID:24584058

Function of YY1 in Long-Distance DNA Interactions., PMID:24575094

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire., PMID:23973221

IL-4 polymorphisms, HRCT score and lung tissue markers in idiopathic pulmonary fibrosis., PMID:23911740

Androgen response element of the glycine N-methyltransferase gene is located in the coding region of its first exon., PMID:23883094

YY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locus., PMID:23531880

Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression., PMID:23416188

Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation., PMID:23248301

Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells., PMID:23027941

YY1-binding sites provide central switch functions in the PARP-1 gene expression network., PMID:22937159

Interaction of the transcription start site core region and transcription factor YY1 determine ascorbate transporter SVCT2 exon 1a promoter activity., PMID:22532872

YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels., PMID:22290437

Galiximab signals B-NHL cells and inhibits the activities of NF-κB-induced YY1- and snail-resistant factors: mechanism of sensitization to apoptosis by chemoimmunotherapeutic drugs., PMID:22267549

Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus., PMID:21982154

Datasheet

Document Download

Anti-YY1 Antibody (R1A72).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-YY1 Antibody (R1A72) [RHD67301]
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