Catalog No.
RHF79201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
Low-density lipoprotein receptor-related protein 2, LRP-2, Glycoprotein 330, gp330, Megalin, LRP2, DBS, LRP2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P98164
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1A08
Autoencoder techniques for survival analysis on renal cell carcinoma., PMID:40373089
Proprotein convertase subtilisin/kexin type 9 contributes to cisplatin-induced acute kidney injury by interacting with cyclase-associated protein 1 to promote megalin lysosomal degradation., PMID:40339661
Development of sandwich enzyme-linked immunosorbent assays quantifying mouse urinary megalin, a novel proximal tubular biomarker., PMID:39374646
Antibrush Border Antibody Disease: A Case Series., PMID:38966682
Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model., PMID:38637347
Clinicopathologic Features of Antibrush Border Antibody Disease., PMID:38344713
The endocytosis receptor megalin: From bench to bedside., PMID:36863658
LRP2 and DOCK8 Are Potential Antigens for mRNA Vaccine Development in Immunologically 'Cold' KIRC Tumours., PMID:36851274
Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors., PMID:35281032
Antibrush Border Antibody Disease: A Case Report and Literature Review., PMID:34693264
Anti-LDL Receptor-Related Protein 2 Nephropathy with Synchronous Primary Kidney Extranodal Marginal Zone Lymphoma., PMID:36751387
Single-cell RNA sequencing confirms IgG transcription and limited diversity of VHDJH rearrangements in proximal tubular epithelial cells., PMID:33184300
Anti-Brush Border Antibody Disease (Anti-LRP2 Nephropathy) Associated With Lupus Nephritis., PMID:32954086
Complete remission of nephrotic syndrome in a young woman with anti-LRP2 nephropathy after immunosuppressive therapy., PMID:32831033
Anti-LRP2 nephropathy with concurrent kidney infiltration by lymphoma., PMID:32701074
A case of immune complex mediated tubulointerstitial disease and nephrotic syndrome: anti LRP-2 Nephropathy with diffuse podocyte effacement., PMID:32472527
Correlation of prechemotherapy urinary megalin ectodomain (A-megalin) levels with the development of cisplatin-induced nephrotoxicity: a prospective observational study., PMID:31791266
Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures., PMID:30993572
Anti-LRP2 Nephropathy With Abundant IgG4-Positive Plasma Cells: A Case Report., PMID:30876746
Anti-TTR Nanobodies Allow the Identification of TTR Neuritogenic Epitope Associated with TTR-Megalin Neurotrophic Activities., PMID:30346709
Tubular disease: Anti-LRP2 nephropathy., PMID:29129926
LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease., PMID:29074737
Inhibition of Leptin-ObR Interaction Does not Prevent Leptin Translocation Across a Human Blood-Brain Barrier Model., PMID:27037668
Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development., PMID:26822476
Renal LRP2 expression in man and chicken is estrogen-responsive., PMID:22868208
Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development., PMID:22354480
Expression of the megalin C-terminal fragment by macrophages during liver fibrogenesis in mice., PMID:21939757
Retinal proliferation response in the buphthalmic zebrafish, bugeye., PMID:21723280
Amyloid-β peptide(1-40) elimination from cerebrospinal fluid involves low-density lipoprotein receptor-related protein 1 at the blood-cerebrospinal fluid barrier., PMID:21585370
Effects of receptor-mediated endocytosis and tubular protein composition on volume retention in experimental glomerulonephritis., PMID:19193726
Low density lipoprotein receptor-related protein-2/megalin is expressed in oligodendrocytes in the mouse spinal cord white matter., PMID:16463279
Low-density lipoprotein receptor-related protein (LRP)-2/megalin is transiently expressed in a subpopulation of neural progenitors in the embryonic mouse spinal cord., PMID:16196028
The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells., PMID:15178744
Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases., PMID:12723989
Evidence that clusterin has discrete chaperone and ligand binding sites., PMID:11772027
Anti-CD69 autoantibodies cross-react with low density lipoprotein receptor-related protein 2 in systemic autoimmune diseases., PMID:11145721
Increased expression of cytoplasmic tail-containing form of gp600/megalin in active Heymann nephritis., PMID:11004703
Circulating and luminal testicular factors affect LRP-2 and Apo J expression in the epididymis following efferent duct ligation., PMID:10670527
A small N-terminal 60-kD fragment of gp600 (megalin), the major autoantigen of active Heymann nephritis, can induce a full-blown disease., PMID:10616840
Identification of low density lipoprotein receptor-related protein-2/megalin as an endocytic receptor for seminal vesicle secretory protein II., PMID:10026171
Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide., PMID:9228033
Low density lipoprotein receptor-related protein-2 expression in efferent duct and epididymal epithelia: evidence in rats for its in vivo role in endocytosis of apolipoprotein J/clusterin., PMID:8862787
Plasminogen activator inhibitor-1 and vitronectin promote the cellular clearance of thrombin by low density lipoprotein receptor-related proteins 1 and 2., PMID:8626514
Glycoprotein 330/low density lipoprotein receptor-related protein-2 mediates endocytosis of low density lipoproteins via interaction with apolipoprotein B100., PMID:7642623
Mouse heparin binding protein-44 (HBP-44) associates with brushin, a high-molecular-weight glycoprotein antigen common to the kidney and teratocarcinomas., PMID:8282724
Visceral-endoderm-like cell lines induce differentiation of murine P19 embryonal carcinoma cells., PMID:1710586
Rat Heymann nephritis antigen is closely related to brushin, a glycoprotein present in early mouse embryo epithelia., PMID:2449897
For research use only. Not for human or drug use.
