Catalog No.
YWN58801
Expression system
E. coli
Species
Bothrops atrox (Barba amarilla) (Fer-de-lance)
Protein length
Val25-Pro255
Predicted molecular weight
27.50 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04971
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Thrombin-like enzyme batroxobin, BX; SVTLE, Bothrops atrox serine proteinase, Defibrase, Fibrinogen-clotting enzyme, Reptilase, Snake venom serine protease (SVSP), Venombin A
Incidence, clinical features, and risk factors of hemocoagulase-induced hypofibrinogenemia: A retrospective real-world study., PMID:38608074
[Determination of the species origin and thrombin-like enzyme content of Bothrops atrox venom by ultra-high performance liquid chromatography-tandem mass spectrometry based on marker peptide]., PMID:36156627
Acute and repeated dose (28 days) toxicity studies in rats and dogs of recombinant batroxobin, a snake venom thrombin-like enzyme expressed from Pichia pastoris., PMID:28161122
The effective control of a bleeding injury using a medical adhesive containing batroxobin., PMID:24487019
Batroxobin binds fibrin with higher affinity and promotes clot expansion to a greater extent than thrombin., PMID:23612970
Functional characterization of recombinant batroxobin, a snake venom thrombin-like enzyme, expressed from Pichia pastoris., PMID:15280019
Two related thrombin-like enzymes present in Bothrops atrox venom., PMID:11050658
The contribution of residues 192 and 193 to the specificity of snake venom serine proteinases., PMID:10636881
Evaluation of kits for the detection of fibrin(ogen) degradation products in dogs., PMID:10499733
Trimeresurus stejnegeri snake venom plasminogen activator. Site-directed mutagenesis and molecular modeling., PMID:9252366
Defibrinogenating enzymes., PMID:9360849
Suppression of cell-transferred experimental autoimmune encephalomyelitis in defibrinated Lewis rats., PMID:8982112
Purification and characterization of a coagulant enzyme, okinaxobin II, from Trimeresurus okinavensis (himehabu snake) venom which release fibrinopeptides A and B., PMID:7725319
Studies on blood coagulation and fibrinolysis in patients bitten by Bothrops jararaca (jararaca)., PMID:2402749
The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-V alpha, -V beta, and -V gamma and their complete amino acid sequences., PMID:3053712
Comparison of the platelet aggregation induced by three thrombin-like enzymes of snake venoms and thrombin., PMID:3291184
Amino acid sequence of a coagulant enzyme, flavoxobin, from Trimeresurus flavoviridis venom., PMID:3170503
Inhibition of batroxobin, a serine proteinase from Bothrops snake venom, by derivatives of benzamidine., PMID:3529503
[Modification of the toxicity of Bothrops atrox poison by interventions in the coagulation and kallikrein system of prey]., PMID:6083965
Modification of batroxobin with activated polyethylene glycol: reduction of binding ability towards anti-batroxobin antibody and retention of defibrinogenation activity in circulation of preimmunized dogs., PMID:6353117
Thrombin-like snake venom proteinases., PMID:7043783
[Studies on blood coagulation systems during defibrinogenation therapy with batroxobin (Bothrops atrox venom) (author's transl)]., PMID:465131
Clottability and cross-linking reactivity of fibrin(ogen) following differential release of fibrinopeptides A and B., PMID:14415
The coagulant enzyme from Bothrops atrox venom (batroxobin)., PMID:1011993
ADP, thrombin, and Bothrops atrox thrombinlike enzyme in platelet-dependent fibrin retraction., PMID:1211467
Separation of human antihemophilic factor (AHF, factor VIII) from fibrinogen by means of defibrase., PMID:54318
For research use only. Not for human or drug use.
