Catalog No.
AHN57801
Biological activity
Measured by its ability to transfer sulfate from PAPS to alpha-Lactose. The specific activity is >800 pmol/min/μg, as measured under the described conditions.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
His32-Ala398
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H3Q3
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Beta-galactose-3-O-sulfotransferase 2, Glycoprotein beta-Gal 3'-sulfotransferase 2, Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2, GP3ST, Galactose-3-O-sulfotransferase 2, Gal3ST-2, GAL3ST2
Susceptibility genes for allergic conjunctivitis revealed by cross-tissue transcriptome-wide association study., PMID:40419210
Novel targets for the treatment and prevention of Alzheimer's disease in the European population, inspiration from amyloid beta and tau protein., PMID:39492919
β(2 → 1)-β(2 → 6) branched graminan-type fructans and β(2 → 1) linear fructans impact mucus-related and endoplasmic reticulum stress-related genes in goblet cells and attenuate inflammatory responses in a fructan dependent fashion., PMID:36656019
The Milk Active Ingredient, 2'-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro., PMID:36613400
Carbohydrate Sulfation As a Mechanism for Fine-Tuning Siglec Ligands., PMID:34661385
Validation of genetic classifiers derived from mouse and human tumors to identify molecular subtypes of colorectal cancer., PMID:34655611
Gut microbiota mediates the effects of inulin on enhancing sulfomucin production and mucosal barrier function in a pig model., PMID:34651635
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors., PMID:34555499
Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins., PMID:34083726
The impact of oligosaccharide content, glycosidic linkages and lactose content of galacto-oligosaccharides (GOS) on the expression of mucus-related genes in goblet cells., PMID:32253406
Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress., PMID:31800974
Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer., PMID:31676359
A Hypoxia-Inducible HIF1-GAL3ST1-Sulfatide Axis Enhances ccRCC Immune Evasion via Increased Tumor Cell-Platelet Binding., PMID:31427440
Fibroblasts Impact Goblet Cell Responses to Lactic Acid Bacteria After Exposure to Inflammatory Cytokines and Mucus Disruptors., PMID:30977971
Sulfatide decreases the resistance to stress-induced apoptosis and increases P-selectin-mediated adhesion: a two-edged sword in breast cancer progression., PMID:30400820
The Association Between Novel Biomarkers and 1-Year Readmission or Mortality After Cardiac Surgery., PMID:29864407
Recurrent cis-SAGe chimeric RNA, D2HGDH-GAL3ST2, in prostate cancer., PMID:27322736
Engineering of a 3'-sulpho-Galβ1-4GlcNAc-specific probe by a single amino acid substitution of a fungal galectin., PMID:25762728
GAL3ST2 from mammary gland epithelial cells affects differentiation of 3T3-L1 preadipocytes., PMID:25532485
Galacto-oligosaccharides may directly enhance intestinal barrier function through the modulation of goblet cells., PMID:25421108
Small intestinal goblet cell proliferation induced by ingestion of soluble and insoluble dietary fiber is characterized by an increase in sialylated mucins in rats., PMID:22718032
Identification of mono- and disulfated N-acetyl-lactosaminyl Oligosaccharide structures as epitopes specifically recognized by humanized monoclonal antibody HMOCC-1 raised against ovarian cancer., PMID:22194598
Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells., PMID:22101519
Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients., PMID:22101162
The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth., PMID:21525289
3'-Sulfo-Le(x) is important for regulation of integrin subunit alphaV., PMID:20695481
Polyoxometalates as effective inhibitors for sialyl- and sulfotransferases., PMID:19508952
Alteration of the expression profiles of acidic mucin, sialytransferase, and sulfotransferases in the intestinal epithelium of rats infected with the nematode Nippostrongylus brasiliensis., PMID:18716796
Porcine, mouse and human galactose 3-O-sulphotransferase-2 enzymes have different substrate specificities; the porcine enzyme requires basic compounds for its catalytic activity., PMID:15926885
Gal3ST-2 involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins., PMID:15921657
Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide., PMID:14701868
A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO(4)-3)Galbeta1-4(Fucalpha1-3)GlcNAc., PMID:11356829
Molecular cloning and characterization of a novel human galactose 3-O-sulfotransferase that transfers sulfate to gal beta 1-->3galNAc residue in O-glycans., PMID:11333265
Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans., PMID:11323440
For research use only. Not for human or drug use.
