Catalog No.
AHN00601
Biological activity
Measured by its ability to bind biotinylated alpha-D Mannose-PAA in a functional ELISA.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Thr46-Leu209
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6EIG7
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DC-associated C-type lectin 2, DECTIN2, Dendritic cell-associated C-type lectin 2, CLECSF10, CLEC6A, C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dectin-2
Proteomic and Genetic predictors and risk scores of cardiovascular diseases in persons living with HIV., PMID:40463557
A prognostic model based on CLEC6A predicts clinical outcome of breast cancer patients., PMID:38852520
Prognostic impact and immunotherapeutic implications of NETosis-related gene signature in gastric cancer patients., PMID:38146607
Integration of Non-Coding RNA and mRNA Profiles Reveals the Mechanisms of Rumen Development Induced by Different Types of Diet in Calves., PMID:37239453
Investigation of Causal Effects of Protein Biomarkers on Cardiovascular Disease in Persons With HIV., PMID:36580481
Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study., PMID:35835712
Supplementation with N-carbamoylglutamate during the transition period improves the function of neutrophils and reduces inflammation and oxidative stress in dairy cows., PMID:35637005
A Human Dectin-2 Deficiency Associated With Invasive Aspergillosis., PMID:33733279
Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients., PMID:31861989
Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2., PMID:31371767
Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit-related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2., PMID:31251950
Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2., PMID:30443026
Pegbovigrastim treatment affects gene expression in neutrophils of pasture-fed, periparturient cows., PMID:29960779
The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages., PMID:29666621
The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells., PMID:29616019
Massively parallel targeted resequencing reveals novel genetic variants associated with aspergillosis in paediatric patients with haematological malignancies., PMID:29363912
Mechanism of pathogen recognition by human dectin-2., PMID:28652405
Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells., PMID:27358401
C-type Lectin Receptor Expression on Human Basophils and Effects of Allergen-Specific Immunotherapy., PMID:27354239
Allergen-Specific Immunotherapy Alters the Frequency, as well as the FcR and CLR Expression Profiles of Human Dendritic Cell Subsets., PMID:26863539
Enhanced Humoral Responses Induced by Targeting of Antigen to Murine Dendritic Cells., PMID:26346906
Pullulan: a new cytoadhesive for cell-mediated cartilage repair., PMID:25889571
Recognition of Aspergillus fumigatus hyphae by human plasmacytoid dendritic cells is mediated by dectin-2 and results in formation of extracellular traps., PMID:25659141
Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation., PMID:24129160
Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors., PMID:23573288
For research use only. Not for human or drug use.
