Catalog No.
AMF68501
Biological activity
Measured by its ability to bind biotinylated rhApoE R2 in a functional ELISA.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Leu1221-Ile2661
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q60841
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Reelin, RELN
Reelin-LRP8 signaling mediates brain dissemination of breast cancer cells via abluminal migration., PMID:40506610
Developmental changes of Reelin-expressing cell populations in the marginal zone of the neocortex of the European wild boar, Sus scrofa., PMID:40498232
Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury., PMID:40442071
Protective genetic variants against Alzheimer's disease., PMID:40409316
WDR62 controls cortical radial migration and callosal projection of neurons in the developing cerebral cortex., PMID:40349858
Case Report: Proteomic analysis of cerebrospinal fluid in a retinoblastoma patient., PMID:40342827
Immunocal®, a cysteine-rich whey protein, rescues reelin and reduces amyloid plaque burden in a transgenic amyloid-β protein precursor (hAβPPSweInd) mouse model of Alzheimer's disease., PMID:40325994
The Nuclear Transitory Zone: A Key Player in the Cerebellar Development., PMID:40314748
Patterns of phosphorylated tau accumulation in a spectrum of acquired and developmental brain lesions associated with refractory epilepsy., PMID:40299318
Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair., PMID:40297980
Apolipoprotein E in Alzheimer's disease: molecular insights and therapeutic opportunities., PMID:40275327
Characterizing the phenotype of pre-Bötzinger Complex neurons in rats., PMID:40252719
A detailed transcriptome study uncovers the epigenetic characteristics associated with Aromatase inhibitor-induced masculinization in Takifugu rubripes larvae gonads., PMID:40240894
Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis., PMID:40207459
Alleviated Neuroinflammation and Increased Neuritogenesis by Palmitic Acid from Cissus quadrangularis., PMID:40189730
Expression of the lymphangiogenic reelin is associated with sex-dependent calcific aortic stenosis in men., PMID:40188710
GRASPs link Reelin to the Golgi during neocortical development to control neuronal migration and dendritogenesis., PMID:40188221
Identification of Deregulated miRNAs and mRNAs Involved in Tumorigenesis and Detection of Glioblastoma Patients Applying Next-Generation RNA Sequencing., PMID:40143207
Reelin marks cocaine-activated striatal neurons, promotes neuronal excitability, and regulates cocaine reward., PMID:40138397
The significance of Itga8 and Vangl2 in kidney development: Insights from yotari mice., PMID:40101650
Genetic or therapeutic disruption of the Reelin/Apoer2 signaling pathway improves inflammatory arthritis outcomes., PMID:40073057
Beyond the brain: Reelin's emerging role in cancer pathways., PMID:40068281
Activation of the Reelin/GSK-3β/p-Tau Signaling Pathway in the Hippocampus of Patients with Temporal Lobe Epilepsy., PMID:40045946
Effects of Oral Administration of the Probiotic Lactobacillus rhamnosus GG on the Proteomic Profiles of Cerebrospinal Fluid and Immunoregulatory Signaling in the Hippocampus of Adult Male Rats., PMID:40031897
Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice., PMID:39999211
The epilepsy-autism phenotype associated with developmental and epileptic encephalopathies: New mechanism-based therapeutic options., PMID:39985505
Reelin Deficiency and Synaptic Impairment in the Adolescent Prefrontal Cortex Following Initial Synthetic Cannabinoid Exposure., PMID:39926699
Dab1 expression level controls Reelin-induced PI3K-Akt activation in early GABAergic neurons., PMID:39919390
Expression Profiling of Reelin (RELN) Gene in Patients With Schizophrenia from North Karnataka., PMID:39897195
Shared molecular signature in Alzheimer's disease and schizophrenia: A systematic review of the reelin signaling pathway., PMID:39894421
Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction., PMID:39892386
Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease., PMID:39868232
Local cortical structure pattern and genetic links in schizophrenia: An MRI and CRISPR/Cas9 study., PMID:39862915
Hippocampal reelin and GAD67 gene expression and methylation in the GFAP.HMOX1 mouse model of schizophrenia., PMID:39798610
Novel KCNQ2 Variants Related to a Variable Phenotypic Spectrum Ranging from Epilepsy with Auditory Features to Severe Developmental and Epileptic Encephalopathies., PMID:39796146
Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease., PMID:39775030
Identification of selective sweep and associated QTL traits in Iranian Ovis aries and Ovis orientalis populations., PMID:39748948
Do specific myelin autoantibodies and increased cerebral dopamine neurotrophic factor in the context of inflammation predict the diagnosis of attention deficit hyperactivity disorder in medication-free children?, PMID:39617068
Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients., PMID:39615603
Heterogeneity in the formation of primary and secondary visual fields during human prenatal development., PMID:39609712
Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model., PMID:39483976
Identification of Potential Growth-Related Proteins in Chick Vitreous during Emmetropization Using SWATH-MS and Targeted-Based Proteomics (MRMHR)., PMID:39408973
The Zebrafish Cerebellar Neural Circuits Are Involved in Orienting Behavior., PMID:39406478
Loss of PHF6 causes spontaneous seizures, enlarged brain ventricles and altered transcription in the cortex of a mouse model of the Börjeson-Forssman-Lehmann intellectual disability syndrome., PMID:39405291
A novel missense variant in the RELN gene in sheep with lissencephaly and cerebellar hypoplasia., PMID:39394905
Herbal Formula Extract Ameliorates Anxiety and Cognitive Impairment via Regulation of the Reelin/Dab-1 Pathway in a Murine Model of Post-Traumatic Stress Disorder., PMID:39339187
Connexin Expression Is Altered in the Eye Development of Yotari Mice: A Preliminary Study., PMID:39334940
Association of single nucleotide polymorphisms and gene-environment interactions with major depressive disorder in Chinese., PMID:39315198
Corrigendum to "The Reelin receptor ApoER2 is a cargo for the adaptor protein complex AP-4: Implications for hereditary spastic paraplegia" [Progr. Neurobiol. 234(2024)102575]., PMID:39294072
CCL5 is essential for axonogenesis and neuronal restoration after brain injury., PMID:39285280
For research use only. Not for human or drug use.
