Catalog No.
AMC97801
Biological activity
Measured by its ability to chemoattract mouse pro‑B cells (BaF3) transfected with human CCR2A. The ED50 for this effect is typically 2-10 ng/mL.
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gln24-Arg96
Nature
Recombinant
Endotoxin level
<1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5SVU3
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Platelet-derived growth factor-inducible protein JE, Small-inducible cytokine A2, Ccl2, Je, Mcp1, Scya2
Antlers on does: An unexpected role of macrophages in deer biology., PMID:40512783
The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models., PMID:40512736
2,5-Dihydroxybenzoic Acid Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Targeting the CCL2-CCR2 Axis to Reduce Lipid Accumulation., PMID:40507104
Identification of genes associated with liver ischemia-reperfusion injury after liver transplantation by WGCNA and PPI network analyses., PMID:40505700
Medin induces pro-inflammatory activation of human brain vascular smooth muscle cells., PMID:40501029
Monoclonal Antibodies to Thyrotropin Receptor With Thyroid-Stimulating Activity Activate the NF-κB Pathway to Induce Chemokine Expression., PMID:40500868
Blood-brain barrier-associated serum proteins as potential diagnostic biomarkers of epilepsy aetiology., PMID:40497531
MCP-1 Is Elevated in the Cerebral Fluid of Children With Tourette Syndrome: Case Series and Literature Review., PMID:40495462
Unveiling immune and signalling proteins in recurrent pregnancy loss: GEO2R analysis sheds light., PMID:40494171
Obtusifolin mitigates acute lung injury and improves cardio-pulmonary functions in acute lung injury model by modulating oxidative stress and NF-κB signaling., PMID:40493249
Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection., PMID:40492741
Myeloid Glutamine Synthetase Protects Against Acute Liver Injury in Mice Independent of Its Enzyme Activity., PMID:40485395
In-silico identification and experimental validation of shared genes and pathways to decipher the molecular links between COPD and MASLD., PMID:40482557
CCL2/CCR4 participates in mast cell-mediated epithelial mesenchymal transition in endometriosis., PMID:40472665
Role of USP10/METTL3/CXCR4 Axis in Immunotherapy of Castration-Resistant Prostate Cancer., PMID:40471642
Integrated profiling of adiponectin and cytokine signaling pathways in high-fat diet-induced MASLD reveals early markers of disease progression., PMID:40467680
Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway., PMID:40467576
Aqueous humor cytokines levels and illuminated microcatheter-assisted circumferential trabeculotomy outcome in open-angle glaucoma patients: a 24-month prospective study., PMID:40463390
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages., PMID:40457421
Identification of potential biomarkers associated with immune cell infiltration patterns in Kawasaki disease via bioinformatics., PMID:40455761
In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410
Curcumin Ameliorates the Effects of High-Fat Diet-induced Obesity via Activating the DNA Repair Response., PMID:40452034
Mefunidone treats pulmonary fibrosis by targeting SDH to regulate fibro-promoting macrophages., PMID:40449267
Differential effects of fentanyl compared to morphine on neuroinflammatory signaling in the brain in EcoHIV-infected mice., PMID:40447886
Defining neuronal responses to the neurotropic parasite Toxoplasma gondii., PMID:40444956
Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway., PMID:40444042
Association of Insertion/Deletion Polymorphisms of MDM2, MCP-1 and VEGF with Esophageal Cancer Risk in North-West Indians: A Case - Control Study., PMID:40439374
Tailored "Three-stage booster" nano-extinguisher for synergistic treatment of severe acute pancreatitis by rectifying mitochondrial dysfunction and inhibiting pancreatic autodigestion., PMID:40436230
Multicystic Interstitial Lung Disease Due to a Novel Biallelic C-C Chemokine Receptor Type 2 Variant., PMID:40432300
Inhibition of MCP1 (CCL2) Enhances Antitumor Activity of NK Cells Against HCC Cells Under Hypoxia., PMID:40430040
Obesity-Related Serum Monocyte Chemoattractant Protein-1 (MCP-1) as a Biomarker of Plaque Instability in Patients Undergoing Carotid Endarterectomy., PMID:40429869
Prognostic Value of Urinary Biomarkers in Proteinuria Progression in IgA Nephropathy Patients Treated with Budesonide., PMID:40428765
Anti-Inflammatory Properties of Yellow Passion Fruit Bagasse Extract and Its Potential Role in Periodontal Wound Healing In Vitro., PMID:40426961
Identifying shared hub genes in LIRI and MASLD through bioinformatics analysis and machine learning., PMID:40425614
Independent and interactive associations of inflammation, vascular homeostasis markers, and childhood trauma with suicide attempt history., PMID:40420573
The relationship between multiple plasma biomarker levels and renal disease activity in Fabry disease., PMID:40420032
[Study on the gene expression and regulation mechanisms of fibroblasts in acute inflammatory response]., PMID:40415617
Prophylactic application of sodium new houttuyfonate to regulate macrophage activation and antifungal infection in intra-abdominal candidiasis model mice., PMID:40412128
Role of lncRNA Xist-miR-124-CCL2 axis in HIV Tat-mediated microglial activation and neuroinflammation., PMID:40406114
Immune-related hub genes and their role in psoriasis pathogenesis., PMID:40404829
Protective Effects of Octyl Gallate Against Deoxynivalenol-Induced Colon Inflammation: Insights from Proteomic and Metabolomic Analyses., PMID:40400552
Regulation of IL-1β gene expression and its function of defense mechanism in rumen epithelial cells from pre- and postweaning calves., PMID:40400194
RiboTag-based RNA profiling uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis: implications for pathogenesis., PMID:40399986
Impact of Smoking on Macrophage-Related Chemokines During Initial Peri-Implantitis: A Prospective Cohort Study., PMID:40399133
Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation., PMID:40397994
Di(2-ethylhexyl) Phthalate (DEHP) Exacerbates Food Allergy via Intestinal Barrier Dysfunction and Enhancing Allergic Sensitization., PMID:40396676
Urinary MCP-1 and VCAM-1 as non-invasive biomarkers for the diagnosis and activity assessment of lupus nephritis., PMID:40388387
POSTN Silencing Ameliorates LL37-Induced Rosacea and Inhibits the JAK2/STAT3 and NF-κB Pathways., PMID:40387439
Alyssin Modulates Inflammatory Mediators Expression in Interleukin-1β-Stimulated Human Periodontal Ligament Cells., PMID:40384003
For research use only. Not for human or drug use.
