Catalog No.
YHC10601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala250
Predicted molecular weight
29.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04798
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytochrome P450 form 6, Hydroperoxy icosatetraenoate dehydratase, Cytochrome P450 1A1, CYP1A1, Cytochrome P450-P1, Cytochrome P450-C, CYPIA1
Investigating the impact of camel whey protein hydrolysate on cyp1a1 and keap1/nrf2 expression in hypoxic stress-affected liver tissue of Oreochromis niloticus., PMID:40493086
Discovery of CYP1A1 Inhibitors for Host-Directed Therapy against Sepsis., PMID:40442943
Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line., PMID:40412367
Identification of Fatty Acid Metabolism Disorder-Related Gene Signature in Septic Cardiomyopathy., PMID:40406682
The ameliorative role of phlorotannin on aflatoxin B1-induced liver oxidative stress and mitochondrial injury is related to the activation of Nrf2 and Nrf1 signaling pathways in broilers., PMID:40405298
Comparison of submerged and air liquid interface exposure: limitations and differences in the toxicological effects evaluated in bronchial epithelial cells., PMID:40379004
Unraveling the molecular mechanisms of PFOA in clear cell renal cell carcinoma through network toxicology and molecular docking strategies., PMID:40359556
[Mechanism of Xiangmei Pills in treating ulcerative colitis based on UHPLC-Q-Orbitrap HRMS and 16S rDNA sequencing of intestinal flora]., PMID:40350808
Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells., PMID:40345318
Polycyclic aromatic hydrocarbon-aryl hydrocarbon receptor signaling regulates chronic inflammation in lung-gut axis., PMID:40320014
Effects of an aryl hydrocarbon receptor ligand on human trophoblast cell development., PMID:40294436
CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner., PMID:40293922
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism., PMID:40281335
Xenobiotic metabolizing gene variants and the risk of male infertility - A systematic review, meta-analysis and in silico analysis., PMID:40271533
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota., PMID:40258529
Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates., PMID:40258480
Exploring the role of gut microbiota modulation in the long-term therapeutic benefits of early MSC transplantation in MRL/lpr mice., PMID:40251524
IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis., PMID:40245547
Species differences in microsomal metabolism of hydroxychloroquine., PMID:40233867
Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism., PMID:40225339
Fulvic acid exhibits antitumor effects in ovarian cancer cells by upregulating cytochrome P450 family 1 subfamily A member 1 expression., PMID:40221570
PM2.5 exacerbates nasal epithelial barrier dysfunction in allergic rhinitis by inducing NLRP3-mediated pyroptosis via the AhR/CYP1A1/ROS axis., PMID:40209413
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363
A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC., PMID:40175891
Activation of the arylhydrocarbon receptor through maternal beta-naphthoflavone exposure in the neonatal kidney., PMID:40175110
Nootkatone (NK), a grapefruit-derived sesquiterpenoid, suppresses UVB-induced damage by regulating NRF2-HO-1 and AhR-CYP1A1 signaling pathways in HaCaT cells., PMID:40151610
Insight into the Role of the Aryl Hydrocarbon Receptor in Bovine Coronavirus Infection by an Integrated Approach Combining In Vitro and In Silico Methods., PMID:40142473
Oxidative Stress, DNA Damage, Ethoxyresorufin-O-deethylase Induction and Neurotoxicity Caused by Environmental Pollutants in Cyprinus carpio (Linnaeus, 1758) from Atatürk Dam Lake (Türkiye)., PMID:40119921
Cigarette smoking modulates m6A modification, affecting the induction of CYP1A1 mRNA by regulating human ARNT and AHRR in A549 cells., PMID:40118351
Knockdown of cytochrome P450 1 A (cyp1a) gene suppresses growth and oxygen tolerance in zebrafish., PMID:40118204
Temperature modulates 17β-estradiol regulation of oogenesis protein expression in the liver of the eurythermal pupfish Cyprinodon nevadensis., PMID:40101872
The regulatory role of ACP5 in the diesel exhaust particle-induced AHR inflammatory signaling pathway in a human bronchial epithelial cell line., PMID:40087344
Phytochemical-Mediated Ah Receptor Activity Is Dependent on Dietary Context., PMID:40077746
Exploring dried ginger essential oil as a therapeutic strategy for 5-FU-induced mucositis: Gut microbiota and tryptophan metabolite IAA-AHR/IL-22/STAT3 signaling axis., PMID:40074099
Farnesoid X receptor regulates CYP1A1 and CYP1B1 and estradiol metabolism in mouse and human cell lines., PMID:40064219
Hepatic Biotransformation in Climbing Perch Anabas testudineus Exposed to Polystyrene Microplastics at Environmentally Relevant Concentrations., PMID:40052469
A novel ingredients recipe derived from Shugan-Hewei Formula targeting chemical carcinogenesis-ROS signaling pathway treated gastroesophageal reflux disease., PMID:40032209
Identification of the key tryptophan metabolic characteristics of Lactiplantibacillus plantarum for aryl hydrocarbon receptor activation and ulcerative colitis alleviation., PMID:40022314
In Vitro Evaluation of Aryl Hydrocarbon Receptor Involvement in Feline Coronavirus Infection., PMID:40006982
Role of Cytochromes P450 in Intestinal Barrier Function: Possible Involvement in the Pathogenesis of Leaky Gut Syndrome., PMID:39971825
Proteomics of stress-induced cardiomyopathy: insights from differential expression, protein interaction networks, and functional pathway enrichment in an isoproterenol-induced TTC mouse model., PMID:39959819
Antiepileptic drugs carbamazepine and valproic acid mediate transcriptional activation of CYP1A1 via aryl hydrocarbon receptor and regulation of estrogen metabolism., PMID:39952367
Astaxanthin protects against environmentally persistent free radical-induced oxidative stress in well-differentiated respiratory epithelium., PMID:39952200
Influence of CYP1A and AhR modulation on polycyclic aromatic hydrocarbon-induced developmental defects in Japanese medaka., PMID:39933340
Predictive value and mediating effect analysis of the AHR-ARNT-CYP1A1 axis for missed abortion related to polycyclic aromatic hydrocarbons exposure., PMID:39929862
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice., PMID:39926427
Skin sensitizers enhance superoxide formation by polycyclic aromatic hydrocarbons via the aldo-keto reductase pathway., PMID:39922325
An endogenous aryl hydrocarbon receptor ligand dysregulates endothelial functions, transcriptome, and phosphoproteome., PMID:39907700
Investigating the role and mechanisms of bisphenol compounds in premature ovarian insufficiency using computational biology and bioinformatics., PMID:39874714
Comparative characterization of organ-specific phase I and II biotransformation enzyme kinetics in salmonid S9 sub-cellular fractions and cell lines., PMID:39873933