Catalog No.
AHG64001
Biological activity
Immobilized human CD6 at 1 μg/mL (100 μL/well) can bind human CD166/ALCAM (Cat #: AHG64001) with a linear range of 0.05-1.2 ng/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ala526
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13740
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166
The interaction of the biocompatible scaffold containing nanochitosan-chitosan-polycaprolactone with telomerase activator and rock inhibitor in propagation and functional properties of corneal endothelial cells., PMID:40446990
The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557
Itolizumab regulates activating and inhibitory signals on effector cells, improving their cytotoxicity against CD318+ tumor cell lines., PMID:40391211
Patient-Derived Colorectal Cancer Extracellular Matrices Modulate Cancer Cell Stemness Markers., PMID:40243470
Notoginsenoside R1 Promotes Osteogenic Differentiation of Dental Pulp Stem Cells via MAPK Pathway., PMID:40116096
Effects and mechanisms of breastmilk stem cells in the treatment of white matter injury in newborn rats., PMID:40055828
CD6 in Human Disease., PMID:39996744
Ligands of CD6: roles in the pathogenesis and treatment of cancer., PMID:39840036
Rhaponticin suppresses the stemness phenotype of gastric cancer stem-like cells CD133+/CD166 + by inhibiting programmed death-ligand 1., PMID:39573998
Comparison of functional characterization of cancer stem cells in different tumor tissues of pseudomyxoma peritonei., PMID:39543711
Differentiation of CD166-positive hPSC-derived lung progenitors into airway epithelial cells., PMID:39387302
AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine., PMID:39369131
Mechanobiological Strategies to Enhance Ovine (Ovis aries) Adipose-Derived Stem Cells Tendon Plasticity for Regenerative Medicine and Tissue Engineering Applications., PMID:39123758
Differential miRNA and Protein Expression Reveals miR-1285, Its Targets TGM2 and CDH-1, as Well as CD166 and S100A13 as Potential New Biomarkers in Patients with Diabetes Mellitus and Pancreatic Adenocarcinoma., PMID:39123454
High-Intensity Focused Ultrasound Increases Facial Adipogenesis in a Swine Model via Modulation of Adipose-Derived Stem Cell Cilia., PMID:39062891
N-Glycan profile of the cell membrane as a probe for lipopolysaccharide-induced microglial neuroinflammation uncovers the effects of common fatty acid supplementation., PMID:39011570
ALCAM-mediated cDC1 CD8 T cells interactions are suppressed in advanced lung tumors., PMID:38887373
The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling., PMID:38790044
Colorectal Cancer Stem Cell Biomarkers: Biological Traits and Prognostic Insights., PMID:38623972
Molecular Determinants Involved in the Docking and Uptake of Tumor-Derived Extracellular Vesicles: Implications in Cancer., PMID:38542421
Osteomacs promote maintenance of murine hematopoiesis through megakaryocyte-induced upregulation of Embigin and CD166., PMID:38458190
Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng., PMID:38322337
Impact of culture media on primary human corneal endothelial cells derived from old donors., PMID:38316204
Clinico-serological associations of urinary activated leukocyte cell adhesion molecule in systemic lupus erythematosus and lupus nephritis., PMID:38294724
Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells., PMID:38280067
Direct Reprogramming of Hepatocytes Into JAK/Stat-Dependent LGR5+ Liver Cells Able to Initiate Intrahepatic Cholangiocarcinoma., PMID:38262709
CD6 and Its Interacting Partners: Newcomers to the Block of Cancer Immunotherapies., PMID:38139340
IL-6 Reduces Spheroid Sizes of Osteophytic Cells Derived from Osteoarthritis Knee Joint via Induction of Apoptosis., PMID:37918800
Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells., PMID:37886483
CD6 triggers actomyosin cytoskeleton remodeling after binding to its receptor complex., PMID:37820034
Targeting Stem Cells and Dysplastic Features With Dual MEK/ERK and STAT3 Suppression in Gastric Carcinogenesis., PMID:37802423
Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells., PMID:37791907
Reversing Uteropathies Including Cancer-Like Changes in Mice by Transplanting Mesenchymal Stromal Cells or XAR Treatment., PMID:37779174
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
Clinical significance of CD166 and HER-2 in different types of gastric cancer., PMID:37537510
Expression analysis of genes involved in the expansion of hematopoietic stem cells (SCF, Flt3-L, TPO, IL-3, and IL-6) in unrestricted somatic stem cells cultured on fibrin., PMID:37116684
Expression of ALCAM in Clinical Colon Cancer and Relationship With Patients' Treatment Responses., PMID:37103072
Mesenchymal stromal cells derived from exfoliated deciduous teeth express neuronal markers before differentiation induction., PMID:37075387
ALCAM, Activated Leukocyte Cell Adhesion Molecule, in Clinical Gastric Cancer and Patient's Response to Chemotherapies., PMID:36974802
The Effects of the Follicle-Stimulating Hormone on Human Follicular Fluid-Derived Stromal Cells., PMID:36768772
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis., PMID:36721767
Increase of ALCAM and VCAM-1 in the plasma predicts the Alzheimer's disease., PMID:36685605
Activated Leukocyte Cell Adhesion Molecule (ALCAM), a Potential 'Seed' and 'Soil' Receptor in the Peritoneal Metastasis of Gastrointestinal Cancers., PMID:36614319
Characterization of CD166 from Nile tilapia (Oreochromis niloticus) displays a broad pathogen recognition spectrum and involved the immune response to microbial aggression., PMID:36603790
Osteogenic Potential of Monosodium Urate Crystals in Synovial Mesenchymal Stem Cells., PMID:36556927
CD6-mediated inhibition of T cell activation via modulation of Ras., PMID:36414966
Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress., PMID:36353616
Pathogenesis of Port-Wine Stains: Directions for Future Therapies., PMID:36292993
Gene Expression and Chondrogenic Potential of Cartilage Cells: Osteoarthritis Grade Differences., PMID:36142513
Therapeutic Targeting of Cancer Stem Cells Prevents Resistance of Colorectal Cancer Cells to MEK Inhibition., PMID:36110381
For research use only. Not for human or drug use.
