Catalog No.
AMD50701
Biological activity
Measured in a cell proliferation assay using mouse mast cells (MC/9‑2). The ED50 for this effect is 0.1‑0.6 ng/mL.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Ser19-Ser178
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
P18893
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL-10, IL10, Cytokine synthesis inhibitory factor, CSIF, Interleukin-10,
Metabolomics Analysis Reveals That Anoectochilus roxburghii Extract Enhances Immunity in Immunosuppressed Rats by Modulating Lipid Metabolism and Amino Acid Metabolism., PMID:40515436
Concentrated Growth Factor Constructs Improve Wound Healing After Third Molar Surgery: A Split-Mouth Randomized Controlled Trial., PMID:40514018
Armored human CAR Treg cells with PD1 promoter-driven IL-10 have enhanced suppressive function., PMID:40512855
Dietary plant-derived lectins induce oxidative stress, metabolic dysfunction, apoptosis and neuroinflammation in mice brain., PMID:40512724
Adropin ameliorates behavioral seizures and the relevant neuroinflammation, oxidative stress, and neural damage in a rat model of pentylenetetrazole-induced seizure potentially by reducing the activation of NF-κB/IkB-α signaling pathway., PMID:40512435
Diagnostic utility of IL-18 plasma levels in distinguishing abdominal from non-abdominal sepsis., PMID:40510342
Large Yellow Croaker Roe Protein Isolates/Gellan Gum Hydrogels Improve the Alleviating Effect of Curcumin on DSS-Induced Colitis., PMID:40509451
A Mixture of Free and Microencapsulated Essential Oils Combined with Turmeric and Tannin in the Diet of Dairy Cows: Effects on Productive Efficiency and Animal Health., PMID:40509055
Pro-Resolving Macrophage-Induced IL-35+ but Not TGF-β1+ Regulatory B Cell Activation Requires the PD-L1/PD-1 Pathway., PMID:40508140
Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
Enhancing Resistance to Enterococcus faecalis: Immunobiotic Lactiplantibacillus plantarum Strains as a Strategy for Malnourished Hosts., PMID:40507039
Concentration-dependent effect of delta-9-tetrahydrocannabinol on epigenetic DNA modifiers in human peripheral blood mononuclear cells., PMID:40506434
HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN-β in podocytes., PMID:40505230
Mechanistic insights into PFOS-induced inflammatory bowel disease: a network toxicology and molecular docking study., PMID:40503787
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway., PMID:40503489
The Effects of Cinepazide Maleate in Conjunction with Edaravone on Cerebral Blood Flow and Neurofunctional Parameters in Individuals with Acute Ischemic Stroke., PMID:40503465
Exploration of biomarkers for inhibitor development in persons with hemophilia A., PMID:40502463
Visnagin treatment attenuates DSS-induced colitis by regulating inflammation, oxidative, stress, and mucosal damage., PMID:40502390
Suppression effect of folate on poly- and perfluoroalkyl substance-induced alterations in lipids and the atherogenic index of plasma in adolescents., PMID:40500729
Anti-Inflammatory effects of Lactobacillus helveticus and Arthrospira platensis on colonic cells inflamed by Crohn's disease-associated Escherichia coli., PMID:40500692
Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
Mucosal barrier function and microbial community of small intestines in sheep in response to dietary energy concentrations., PMID:40499408
Exploring the therapeutic potential of nutraceutical compounds (Curcumin, Quercetin, Epa, Zinc, and Vitamin D) in managing Celiac disease: insights from cellular mechanisms., PMID:40498343
Home-based online exercise training and chronic, low-grade inflammation in cancer patients after curative surgery: secondary analysis of the randomized controlled multicenter CRBP-TS trial., PMID:40498221
Experimental autoimmune encephalomyelitis impairs the immunomodulatory effects of mesenchymal stem cells on splenocyte responses., PMID:40498218
Mesenchymal Stem Cell Secretome Attenuates PrP106-126-Induced Neurotoxicity by Suppressing Neuroinflammation and Apoptosis and Enhances Cell Migration., PMID:40498027
Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function., PMID:40497715
Oral Combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl-2/Bax Pathway., PMID:40497373
Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model., PMID:40497338
SARS-CoV-2 exploits steroidogenic machinery, triggers lipid metabolism for viral replication and induces immune response in Leydig cells of K18-hACE2 mice., PMID:40496014
Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration., PMID:40495198
Intranasal delivery of platelet cell membrane-cloaked Astragaloside IV loaded biomimetic nanoparticles for enhanced therapeutics in acute lung injury mice., PMID:40494449
Giardia increases macrophage production of the anti-inflammatory cytokine interleukin-10 in response to lipopolysaccharide via macrophage galactose binding lectin., PMID:40493880
Combined effects of IRAK inhibition and pioglitazone on hepatic inflammation and apoptosis in a mouse model of MASLD., PMID:40493096
Increasing indoxyl sulfate induces iNOS expression via aryl hydrocarbon receptor leading to microglia hyperactivation in the prefrontal cortex of autism-like offspring rats., PMID:40490210
C1qtnf6 Expression as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma: Implications for Immune Infiltration and Tumor Progression., PMID:40490027
Glucose Parameters, Inflammation Markers, and Gut Microbiota Changes of Gut Microbiome-Targeted Therapies in Type 2 Diabetes Mellitus: a Systematic Review and Meta-Analysis of Randomized Controlled Trials., PMID:40489582
Hypobaric hypoxia promotes the production of IL-10 of lung NKT cells in HAPE rats to fight inflammation., PMID:40489386
Potentially Elevated Rheumatoid Arthritis Risk due to Chemotherapy-Induced Inflammation in Prostate Cancer With Bone Metastasis., PMID:40489190
Anti-Inflammatory/Antioxidant Features of Adipose Tissue Mesenchymal Stem Cells Conditioned Media for Doped TiO2 Nanoparticles in Induced Inflammation., PMID:40489075
High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo., PMID:40488907
Multi-omics interpretation of how lysophospholipids regulate hepatic lipid metabolism and immunity in hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus Lanceolatu) fed high-lipid diets., PMID:40487090
Interferon-gamma and interleukin-10 genetic polymorphisms among the pulmonary tuberculosis caused by Malaysia-specific Mycobacterium tuberculosis strain: SIT745/EAI1-MYS., PMID:40487054
Co-detection of respiratory pathogens in children with Mycoplasma pneumoniae pneumonia: a multicenter study., PMID:40487016
Intradermal priming to intravesical Bacillus Calmette-Guérin in non-muscle invasive bladder cancer: A translational research and phase I clinical trial., PMID:40486869
Salivary and gingival crevicular fluid (GCF) protein biomarkers as proxies of root resorption following orthodontic tooth movement. A systematic review., PMID:40485969
Harnessing the Power of Chlorogenic Acid: Inhibiting IL-2-Mediated Treg Upregulation to Combat Post-Traumatic Osteomyelitis., PMID:40485518
Executive Function Decline and Its Association With TNF-α in the Later Stages of Post-Acute Sequelae of COVID., PMID:40485151
Enterococcus faecalis hijacks FABP2 to activate quorum-sensing signals and aggravate Crohn's disease by inducing gut dysbiosis., PMID:40484632
Anti-inflammatory effects of Rehmannia glutinosa polysaccharide on LPS-induced acute liver injury in mice and related underlying mechanisms., PMID:40484254
For research use only. Not for human or drug use.
