Catalog No.
AHC21101
Biological activity
Measured by its ability to phosphorylate creatine. The specific activity is >1,900 pmol/min/μg, as measured under the described conditions.
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro2-Lys381
Nature
Recombinant
Endotoxin level
<1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
P06732
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Creatine kinase M chain, Creatine phosphokinase M-type, Creatine kinase M-type, CKMM, CKM, CPK-M, M-CK
Optimized efficient screening for Duchenne muscular dystrophy carriers using proto-oncogene tyrosine-protein kinase receptor Ret., PMID:40244132
Ligustilide covalently binds to Cys254 of the creatine kinase, M-type protein, ameliorating acute myocardial ischemia by enhancing the creatine phosphate level., PMID:40007343
Decompression sickness-induced skeletal muscle injury: an animal model and pathological analysis., PMID:39329065
Acute responses of strength-related gene expressions to maximum strength and force sense acuity., PMID:38812641
Dantrolene and coenzyme Q10 as a suggested combination therapy to statin-induced myopathy in high fat diet rats: A possible interference with ROS/ TGF-β / Smad4 signaling pathway., PMID:38508403
Impact of L-Arginine on diabetes-induced neuropathy and myopathy: Roles of PAI-1, Irisin, oxidative stress, NF-κβ, autophagy and microRNA-29a., PMID:38430848
Diagnostic Accuracy of Creatine Kinase Isoenzyme-MM Test in Newborn Screening for Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis., PMID:38350306
ASSOCIATION OF SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1B1 GENE POLYMORPHISM WITH RESPONSE TO ATORVASTATIN AND ASSOCIATED MYOPATHY IN IRAQI DYSLIPIDEMIA PATIENTS., PMID:38069850
Building a Nucleic Acid Nanostructure with DNA-Epitope Conjugates for a Versatile Approach to Electrochemical Protein Detection., PMID:38032341
Biomonitoring the skeletal muscle metabolic dysfunction in knee osteoarthritis in older adults: Is Jumpstart Nutrition® Supplementation effective?, PMID:38024172
Creatine kinase and its isoenzymes in the serum and cerebrospinal fluid of healthy canines., PMID:37985467
Agarose gel electrophoresis pattern of serum creatine kinase and lactate dehydrogenase isoenzymes in zoo-managed Asian elephants (Elephas maximus)., PMID:36927856
A subcritical water extract of soil grown Zingiber officinale Roscoe: Comparative analysis of antioxidant and anti-inflammatory effects and evaluation of bioactive metabolites., PMID:36843947
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy., PMID:36734200
Newborn screening and genomic analysis of duchenne muscular dystrophy in Henan, China., PMID:36516925
[Advance in research on genetic polymorphisms associated with athletic ability]., PMID:35446984
Selenium Supplementation Alters IL-1β and IL-6 Protein Levels in Contusion Model Rats., PMID:35234013
Elevation in creatine kinase isoenzyme-MM associated with hepatocellular carcinoma: a case report and review of literature., PMID:35199319
Smad2 and Smad3 expressed in skeletal muscle promote immobilization-induced bone atrophy in mice., PMID:34710825
[Study on newborn screening for Duchenne muscular dystrophy and diagnostic strategy]., PMID:33974249
Prevalence of work-related musculoskeletal disorders among Egyptian printing workers evidenced by using serum biomarkers of inflammation, oxidative stress, muscle injury, and collagen type I turnover., PMID:33295250
Muscular G9a Regulates Muscle-Liver-Fat Axis by Musclin Under Overnutrition in Female Mice., PMID:32994276
Structure-activity relationship analysis of dammarane-type natural products as muscle-type creatine kinase activators., PMID:32738969
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase., PMID:32372868
Regional hypothermia attenuates secondary-injury caused by time-out application of tourniquets following limb fragments injury combined with hemorrhagic shock., PMID:31752982
Levels of C-reactive protein, creatine kinase-muscle and aldolase A are suitable biomarkers to detect the risk factors for osteoarthritic disorders: A novel diagnostic protocol., PMID:30858938
Do ACE and CKMM gene variations have potent effects on physical performance in inactive male adolescents?, PMID:30710235
MENS-associated increase of muscular protein content via modulation of caveolin-3 and TRIM72., PMID:30628834
Identification of Blood-Brain Barrier-Permeable Proteins Derived from a Peripheral Organ: In Vivo and in Vitro Evidence of Blood-to-Brain Transport of Creatine Kinase., PMID:30495961
[Development and application of CK-MB specific monoclonal antibodies]., PMID:28959871
Characterization of a functional recombinant human creatine kinase-MB isoenzyme prepared by tandem affinity purification from Escherichia coli., PMID:28432439
Optimum polygenic profile to resist exertional rhabdomyolysis during a marathon., PMID:28257486
Characterization of a Blood Spot Creatine Kinase Skeletal Muscle Isoform Immunoassay for High-Throughput Newborn Screening of Duchenne Muscular Dystrophy., PMID:28209627
ACTN3 X-allele carriers had greater levels of muscle damage during a half-ironman., PMID:27913923
Nuclear Magnetic Resonance-Based Metabolomics of Human Filtered Serum: A Great White Hope in Appraisal of Chronic Stable Angina and Myocardial Infarction., PMID:33626845
Biomarker evaluation of skeletal muscle toxicity following clofibrate administration in rats., PMID:27020044
[COMPARISON OF EFFECTIVENESS BETWEEN PARA-MEDIAN INCISION MINIMALLY INVASIVE AND OPEN TRANSFORAMINAL LUMBAR INTERBODY FUSION FOR SINGLE SEGMENTAL LUMBAR DEGENERATIVE DISEASE]., PMID:26749734
Association of Plasma Heat Shock Protein 70, Interleukin 6, and Creatine Kinase Concentrations in a Healthy, Young Adult Population., PMID:26664829
Creatine kinase isoenzyme activity during and after an ultra-distance (200 km) run., PMID:28479667
[Evaluation of the Creatine Kinase MB Activity Assay Kit]., PMID:27509718
Arginylation of myosin heavy chain regulates skeletal muscle strength., PMID:25017061
Refinement of tourniquet-induced peripheral ischemia/reperfusion injury in rats: comparison of 2 h vs 24 h reperfusion., PMID:24585935
Diagnostic significance of total creatine kinase and its isoform in tubal ectopic pregnancy., PMID:23876027
Genetic polymorphisms associated with exertional rhabdomyolysis., PMID:23543093
[Characterization of unusual macro CK1 of IgG3kappa-cK-MM type detected in the serum of a patient with idiopathic thrombocytopenic purpura]., PMID:23157112
An integrated chip for rapid, sensitive, and multiplexed detection of cardiac biomarkers from fingerprick blood., PMID:21807497
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels., PMID:21706313
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels., PMID:21516340
Electrophoretic fractionation of creatine kinase isoenzymes and macroenzymes in clinically healthy dogs and cats and preliminary evaluation in central neurologic disease., PMID:20698943
Development and validation of a sensitive immunoassay for the skeletal muscle isoform of creatine kinase., PMID:18976957
For research use only. Not for human or drug use.
