Catalog No.
AHB16401
Biological activity
Measured by its ability to hydrolyze the 5'-phosphate groups from the substrate adenosine-5'-triphosphate (ATP). The orthophosphate product is measured by a Malachite Green Phosphate Detection Kit. The specific activity is >70,000 pmol/min/µg, as measured under the described conditions.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Gln44-Pro485
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
O75355
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ecto-ATPase 3, Ectonucleoside triphosphate diphosphohydrolase 3, CD39L3, CD39 antigen-like 3, ENTPD3, HB6, Ecto-apyrase 3, Ecto-ATPDase 3, Ecto-ATP diphosphohydrolase 3, NTPDase 3
Purinergic System Transcript Changes in the Dorsolateral Prefrontal Cortex in Suicide and Major Depressive Disorder., PMID:40076453
Integrated transcriptomic analysis reveals dysregulated immune infiltration and pro-inflammatory cytokines in the secretory endometrium of recurrent implantation failure patients., PMID:39872439
Extracellular Vesicles Derived Ectonucleoside Triphosphate Diphosphohydrolase 3 Alleviates Mitochondrial Dysfunction of Osteoarthritis Chondrocytes via Ectonucleotide Pyrophosphatase/Phosphodiesterase 1-Induced Suppression of the AKT/Notch2 Pathway., PMID:39569601
Expression and Hormonal Regulation of Entpd3 at Various Estrous Cycle Stages in the Mouse Uterus., PMID:39567465
Adenosine Metabolism Pathway Alterations in Frontal Cortical Neurons in Schizophrenia., PMID:39404420
Downregulated antisense lncRNA ENTPD3-AS1 contributes to the development of lung adenocarcinoma., PMID:38455397
Integration of Metabolomics and Transcriptomics to Reveal the Metabolic Characteristics of Exercise-Improved Bone Mass., PMID:37049535
Study on the role and pharmacology of cuproptosis in gastric cancer., PMID:37007099
Gene expression signatures in PCB-exposed Slovak children in relation to their environmental exposures and socio-physical characteristics., PMID:35420343
ENTPD3 Marks Mature Stem Cell-Derived β-Cells Formed by Self-Aggregation In Vitro., PMID:34380694
SNP-mediated lncRNA-ENTPD3-AS1 upregulation suppresses renal cell carcinoma via miR-155/HIF-1α signaling., PMID:34218253
Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism., PMID:33631144
Biochemical analysis of ectonucleotidases on primary rat vascular smooth muscle cells and in silico investigation of their role in vascular diseases., PMID:32473244
Comparative RNA-Seq Analysis of Differentially Expressed Genes in the Epididymides of Yak and Cattleyak., PMID:32030088
GATA Binding Protein 3 Boosts Extracellular ATP Hydrolysis and Inhibits Metastasis of Breast Cancer by Up-regulating Ectonucleoside Triphosphate Diphosphohydrolase 3., PMID:31754326
An exome-wide rare variant analysis of Korean men identifies three novel genes predisposing to prostate cancer., PMID:31748686
P2X7 Purinergic Receptor Is Involved in the Pathophysiology of Mania: a Preclinical Study., PMID:31729632
Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders., PMID:27416040
Investigation into effects of antipsychotics on ectonucleotidase and adenosine deaminase in zebrafish brain., PMID:26156500
Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord., PMID:25717362
Deregulation of purine metabolism in Alzheimer's disease., PMID:25311278
Endotoxin-induced effects on nucleotide catabolism in mouse kidney., PMID:22108548
E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings., PMID:18201730
Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish., PMID:17868657
For research use only. Not for human or drug use.
