Catalog No.
YHN56401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val40-Glu320
Predicted molecular weight
34.3 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y4F1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FERM, RhoGEF and pleckstrin domain-containing protein 1, Chondrocyte-derived ezrin-like protein, CDEP, PH domain-containing family C member 2, Pleckstrin homology domain-containing family C member 2, FARP1, PLEKHC2, FERM, ARHGEF and pleckstrin domain-containing protein 1
Conserved region of human TDP-43 is structurally similar to membrane binding protein FARP1 and protein chaperons BAG6 and CYP33., PMID:39583578
ANKK1 Is a Wnt/PCP Scaffold Protein for Neural F-ACTIN Assembly., PMID:39409035
Multicenter Validation of lncRNA and Target mRNA Diagnostic and Prognostic Biomarkers of Acute Ischemic Stroke From Peripheral Blood Leukocytes., PMID:38979813
Environmentally dependent and independent control of 3D cell shape., PMID:38636520
Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis., PMID:37390986
Effect of genetic polymorphisms on outcomes following nivolumab for advanced renal cell carcinoma in the SNiP-RCC trial., PMID:36729213
Estimation of genetic parameters and single-step genome-wide association studies for milk urea nitrogen in Holstein cattle., PMID:36460511
DNA methylation alternation in Stanford- A acute aortic dissection., PMID:36309656
circFARP1 enables cancer-associated fibroblasts to promote gemcitabine resistance in pancreatic cancer via the LIF/STAT3 axis., PMID:35045883
FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma., PMID:34731623
FMRF-NH2 -related neuropeptides in Biomphalaria spp., intermediate hosts for schistosomiasis: Precursor organization and immunohistochemical localization., PMID:34041754
Effects of lifestyle interventions on epigenetic signatures of liver fat: Central randomized controlled trial., PMID:33938135
Identification of "regulation of RhoA activity panel" as a prognostic and predictive biomarker for gastric cancer., PMID:33288739
FARP-1 deletion is associated with lack of response to autism treatment by early start denver model in a multiplex family., PMID:32588496
The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors., PMID:32471987
FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer., PMID:32029704
TMT-based quantitative proteomics revealed follicle-stimulating hormone (FSH)-related molecular characterizations for potentially prognostic assessment and personalized treatment of FSH-positive non-functional pituitary adenomas., PMID:31832114
FARP1 Facilitates Cell Proliferation Through Modulating MAPK Signaling Pathway in Cutaneous Melanoma., PMID:31021836
Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of bone., PMID:30281149
Structural analyses of FERM domain-mediated membrane localization of FARP1., PMID:29992992
A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes., PMID:29791858
Combination of TNM staging and pathway based risk score models in patients with gastric cancer., PMID:29231991
A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity., PMID:28860633
Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice., PMID:28172500
Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers., PMID:27617035
Inhibition of Cdc42 and Rac1 activities in pheochromocytoma, the adrenal medulla tumor., PMID:27355516
Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression., PMID:26911374
The action of neuropeptide AF on passive avoidance learning. Involvement of neurotransmitters., PMID:26639667
Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells., PMID:26471833
MAP4K4 Is a Threonine Kinase That Phosphorylates FARP1., PMID:26422651
The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction., PMID:25668492
Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1., PMID:24899721
Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2., PMID:23375260
The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization., PMID:23209303
Novel mutation and three other sequence variants segregating with phenotype at keratoconus 13q32 susceptibility locus., PMID:22045297
FARP1 promotes the dendritic growth of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling., PMID:19217374
Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors., PMID:9425278
For research use only. Not for human or drug use.
