Catalog No.
YHC02401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Asp175
Predicted molecular weight
22.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02792
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ferritin light chain, FTL, Ferritin L subunit
Haplotypic resolution of the challenging genomic regions of MHC and KIR using a combination of targeted sequencing and a novel assembly pipeline., PMID:40464686
Hyperlipidemia Triggers Trophoblast Cell Dysfunction and Preeclampsia via the AMPK/GATA3/FTL Pathway., PMID:40421527
Ferroptosis effects and behavioral changes associated with high accumulation and low elimination percentage of silver in brain following a 28-day nasal instillation of silver nanoparticles in mice., PMID:40409664
Muscle mTOR controls iron homeostasis and ferritinophagy via NRF2, HIFs and AKT/PKB signaling pathways., PMID:40293459
Electroacupuncture Ameliorates Chronic Inflammatory Pain and Depression Comorbidity by Inhibiting Nrf2-Mediated Ferroptosis in Hippocampal Neurons., PMID:40257585
Sevoflurane Inhibits the Proliferation of Neural Precursor Cells and Neural Migration of Mice by Inducing Iron Metabolism Disorders., PMID:40202153
Evolutionary dynamics of PEG10 and its interacting proteins during early and late-stage placental development in ruminants., PMID:40180104
SCARA5 might be one potential marker for CC and promoted Ferroptosis by FTL., PMID:40084377
Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies., PMID:40082954
Hexavalent chromium induces ferroptosis in small intestinal tissue of broilers through GPX4/HMGB1/p38-MAPK pathway., PMID:40048981
Gastrodin promotes ferroptosis in CRC cells by inhibiting SKP2 to reduce NCOA4 ubiquitination., PMID:40048831
SRC involves in lysosomal function and regulates ferroptosis in polycystic ovary syndrome., PMID:40045372
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism., PMID:40032029
Fucoxanthin Ameliorates Kidney Injury by CCl4-Induced via Inhibiting Oxidative Stress, Suppressing Ferroptosis, and Modulating Gut Microbiota., PMID:40028144
Analysis of ferroptosis-related key genes and regulatory networks in diabetic foot ulcers., PMID:40024299
Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis., PMID:39988734
Novel ferritin L-chain gene variant in a case of hereditary hyperferritinemia-cataract syndrome without family history., PMID:39987942
Antimony-induced hippocampal neuronal impairment through ferroptosis activation from NCOA4-mediated ferritinophagy., PMID:39954839
Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments., PMID:39906141
Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels., PMID:39849491
Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks., PMID:39849110
Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis., PMID:39807704
β-elemene, a sesquiterpene constituent from Curcuma phaeocaulis inhibits the development of endometriosis by inducing ferroptosis via the MAPK and STAT3 signaling pathways., PMID:39800242
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis., PMID:39786573
Itchy E3 Ubiquitin Ligase-Mediated Ubiquitination of Ferritin Light Chain Contributes to Endothelial Ferroptosis in Atherosclerosis., PMID:39769287
Genetic Landscape of Dystonia in Asian Indians., PMID:39749944
Berberine alleviates AGEs-induced ferroptosis by activating NRF2 in the skin of diabetic mice., PMID:39735782
Liraglutide and GLP-1(9-37) alleviated hepatic ischemia-reperfusion injury by inhibiting ferroptosis via GSK3β/Nrf2 pathway and SMAD159/Hepcidin/FTH pathway., PMID:39693850
Activation of ferritin light chain (FTL) by transcription factor salmonella pathogenicity island 1 modulates glycolysis to drive metastasis of ovarian cancer cells., PMID:39675923
Structural Analysis of Variants of the Ferritin Light Chain Protein and Its Relationship with Neuroferritinopathy., PMID:39641997
Regulatory role of AMPK/Nrf2 signaling pathway in sevoflurane-enhanced intestinal protection against ischemia-reperfusion injury., PMID:39581489
Pathological Characteristics of Ferroptosis in Kidney Tissues in Type 2 Diabetic Patients with Diabetic Kidney Disease., PMID:39502451
The critical involvement of monocytes/macrophages in the pathogenesis of primary Sjögren's syndrome: New evidence from Mendelian randomization and single-cell sequencing., PMID:39497977
Single-cell transcriptional analysis of murine norovirus infection in a human intestinal cell line., PMID:39475272
ALKBH5 modulation of ferroptosis in recurrent miscarriage: implications in cytotrophoblast dysfunction., PMID:39434797
Genome-wide exploration of the CONSTANS-like (COL) gene family and its potential role in regulating plant flowering time in foxtail millet (Setaria italica)., PMID:39424865
Metabolic alterations in fibroblasts of patients presenting with the MPAN subtype of neurodegeneration with brain iron accumulation (NBIA)., PMID:39419454
Arsenic induces ferroptosis in HTR-8/SVneo cells and placental damage., PMID:39414034
Proteomic Characterization of Urinary Exosomes with Pancreatic Cancer by Phosphatidylserine Imprinted Polymer Enrichment and Mass Spectrometry Analysis., PMID:39392357
Characterization of serum proteomic and inflammatory profiling at early stage of iron deficiency in weaned piglets., PMID:39296492
Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide., PMID:39294687
Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells., PMID:39294443
S. glabra exerts anti-lung cancer effects by inducing ferroptosis and anticancer immunity., PMID:39260134
Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC., PMID:39159723
Flaxseed Oil Attenuates Intestinal Damage by Regulating Ferroptosis Signaling Pathway Following LPS Challenge in Piglets., PMID:39148171
Ferroptosis promotes valproate-induced liver steatosis in vitro and in vivo., PMID:39147356
Sorbitol metabolism plays a key role in the differential accumulation of sugar in two plum cultivars., PMID:39126176
Targeting OGF/OGFR signal to mitigate doxorubicin-induced cardiotoxicity., PMID:39122201
Transcriptomics pave the way into mechanisms of cobalt and nickel toxicity: Nrf2-mediated cellular responses in liver carcinoma cells., PMID:39088892
For research use only. Not for human or drug use.
