Catalog No.
YHD89901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Leu82
Predicted molecular weight
11.2 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30536
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PKBS, TSPO, MBR, PBR, BZRP, Translocator protein, Peripheral-type benzodiazepine receptor, Mitochondrial benzodiazepine receptor
Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism., PMID:40489695
Mechanism of Dihydroartemisinin in activating macrophages to enhance host resistance to malaria., PMID:40450979
TSPO PET in multiple sclerosis: Emerging insights into pathophysiology, prognosis, and treatment monitoring., PMID:40450829
Whole-Body [18F]DPA-714 Kinetic Assessment Using PET/CT Scanner with Long Axial Field of View., PMID:40441893
Biology-driven therapies of CAR T immune effector cell-associated neurotoxicity syndrome., PMID:40438973
TSPO Ligand 2-Cl-MGV-1 Mitigates Traumatic Brain Injury (TBI) in a Mouse Model., PMID:40429994
Greater neuroimmune system deficit in women than men with alcohol use disorder., PMID:40412787
Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis., PMID:40379482
TSPO deficiency exacerbates acute brain damage after intracerebral hemorrhage in male mice., PMID:40370317
Cyclooxygenase-1 and cyclooxygenase-2 densities measured using positron emission tomography are not altered in the brains of individuals with stable multiple sclerosis., PMID:40367389
Dampening of Microglial Activation With Nasal Foralumab Administration in Moderate Alzheimer's Disease Dementia., PMID:40359013
Associations between chronic active lesions and clinical outcomes in multiple sclerosis: A systematic literature review., PMID:40357663
Brain inflammation and its predictive value for post-operative pain in total knee arthroplasty patients., PMID:40354834
Evidence for brain glial activity in chronic migraine patients: a [11C] PBR28 PET/MR study., PMID:40327090
Adenosine transmission from hypothalamic tanycytes to AGRP/NPY neurons regulates energy homeostasis., PMID:40316705
A mini-review: Application of the radiopharmaceutical [18F]DPA-714 in neuroinflammation research in post-SARS-CoV-2 patients., PMID:40315803
Exploring inflammation-related protein expression and its relationship with TSPO PET in Alzheimer's disease., PMID:40289873
TSPO participates in the pathogenesis of diabetic periodontitis related to mitophagy., PMID:40280203
Age-Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice., PMID:40275629
Benzoxazolone-based FITC-conjugated fluorescent probe for locating in-vivo expression level of translocator protein (TSPO) during lung inflammation., PMID:40259117
Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis., PMID:40248672
Sex- and region-dependent neuroinflammation in Alzheimer's disease., PMID:40247152
Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial., PMID:40228108
A new nano-encapsulated TSPO ligand reduces neuroinflammation and improves cognitive functions in Alzheimer's disease model., PMID:40225565
Neuroinflammation at the Neuroforamina and Spinal Cord in Patients with Painful Cervical Radiculopathy and Pain-Free Participants: An [11C]DPA713 PET/CT Proof-of-Concept Study., PMID:40217878
Tspo Depletion Exacerbates Steatosis Through Fatty Acid Uptake., PMID:40195072
Mitochondrial translocator-protein ligand etifoxine reduces pain symptoms and protects against motor dysfunction development following peripheral nerve injury in rats., PMID:40189017
[11C]ER176 images brain inflammation across TSPO genotypes and colocalizes with tau., PMID:40187909
Effects of Cigarette Smoking and 3-Day Smoking Abstinence on Translocator Protein 18 kDa Availability: A [18F]FEPPA Positron Emission Tomography Study., PMID:40184237
Radiation dosimetry of the 18 kDa translocator protein ligand [18F]PBR111 in humans., PMID:40179687
Synthesis and evaluation of TSPO-targeting radioligand [18F]F-TFQC for PET neuroimaging in epileptic rats., PMID:40177559
Peripheral and central inflammation in depression: How large is the gap and can we bridge it with PET neuroimaging and neural-derived extracellular vesicles?, PMID:40174479
PCSK9 Regulates Cardiac Mitochondrial Cholesterol by Promoting TSPO Degradation., PMID:40171648
Cholesterol-dependent enzyme activity of human TSPO1., PMID:40146857
The role of nuclear medicine in neurodegenerative diseases: a narrative review., PMID:40124351
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors., PMID:40063900
PK 11195 derivatives: exploring the influence of amide and heterocyclic substitution on A147T TSPO discrimination., PMID:40060999
Emerging translocator protein-positron emission tomographic imaging improves detection of focal cortical dysplasia., PMID:40055993
Astrocyte gap junction dysfunction activates JAK2-STAT3 pathway to mediate inflammation in depression., PMID:40054743
Qilong capsule regulates microglial function and inhibits platelet activation after multiple cerebral infarctions by regulating the P2Y12/AC/cAMP signalling pathway., PMID:40054638
Microglial Activation Visualized by [18F]-DPA714 PET Is a Potential Marker of Severity and Prognosis for Anti-LGI1 Encephalitis., PMID:40052391
The impact and mechanisms of YL-IPA08, a potent ligand for the translocator protein (18 kDa) on protection against LPS-induced depression and cognitive dysfunction in rodents., PMID:40047959
Post-mortem validation of in vivo TSPO PET as a microglial biomarker., PMID:40036275
A New Approach to Synthesizing Carbon-11-PBR28 and its Clinical Validation in ALS Patients., PMID:40012394
Exoproteomic Evidence for BcTSPO-Mediated Regulation of Virulence Factors in Bacillus cereus., PMID:39981793
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET Imaging., PMID:39975931
Integrating bulk RNA-seq and scRNA-seq data to explore diverse cell death patterns and develop a programmed cell death-related relapse prediction model in pediatric B-ALL., PMID:39955305
Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study., PMID:39919076
Hybrid PET/MRI Imaging of 18F-Fluorodeoxyglucose and 18-kDa Translocator Protein for Presurgical Localization in Refractory Epilepsy., PMID:39915832
Fluor NMR study of amino acid derived ligand to study TSPO., PMID:39914698
For research use only. Not for human or drug use.
