Catalog No.
YVV43501
Expression system
E. coli
Species
Porcine deltacoronavirus
Protein length
Ala2509-Gln2815
Predicted molecular weight
36.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
UVJ47558.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 2% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
3C-like proteinase, 3CL-PRO, Main protease, Mpro, Non-structural protein 5, nsp5, ORF1ab polyprotein
Cleavage of the selective autophagy receptor NBR1 by the PDCoV main protease NSP5 impairs autophagic degradation of the viral envelope protein., PMID:40047225
Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3., PMID:38289117
Cleavage of HDAC6 to dampen its antiviral activity by nsp5 is a common strategy of swine enteric coronaviruses., PMID:38289103
Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3., PMID:37801439
Porcine Deltacoronavirus Infection Cleaves HDAC2 to Attenuate Its Antiviral Activity., PMID:35916536
Coronaviruses Nsp5 Antagonizes Porcine Gasdermin D-Mediated Pyroptosis by Cleaving Pore-Forming p30 Fragment., PMID:35012343
Porcine Deltacoronavirus nsp5 Cleaves DCP1A To Decrease Its Antiviral Activity., PMID:32461317
Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I., PMID:31129785
Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2., PMID:28250121
Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO., PMID:27984784
For research use only. Not for human or drug use.
