Catalog No.
YHC00701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr37-Leu340
Predicted molecular weight
35.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02750
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LRG1, LRG, Leucine-rich alpha-2-glycoprotein
LRG1 in cancer: mechanisms, potential therapeutic target, and use in clinical diagnosis., PMID:40493117
Single-cell RNA sequencing identifies cellular heterogeneity in endothelial and epithelial cells associated with nitrogen dioxide-induced acute lung injury., PMID:40403690
Revealing the multiple faces of LRG1: gene expression, structure, function, and therapeutic potential., PMID:40368176
Efficient diagnosis for endoscopic remission in Crohn's diseases by the combination of three non-invasive markers., PMID:40355822
Development of a novel histidine-rich glycoprotein measurement system as a biomarker for sepsis., PMID:40324742
Rinsenoside Rg1 and its involvement in Hippo-YAP signaling pathway alleviating symptoms of depressive-like behavior., PMID:40281108
Fecal Microbiota and Associated Metabolites Are Minimally Affected by Ten Weeks of Resistance Training in Younger and Older Adults., PMID:40278724
LRG1 Alters Pericyte Phenotype and Compromises Vascular Maturation., PMID:40277918
Serum proteomics of adults with acute liver failure provides mechanistic insights and attractive prognostic biomarkers., PMID:40242314
Exploration of Leucine-Rich Alpha-2 Glycoprotein 1 (LRG1) and Its Association with Proangiogenic Mediators in Sickle Cell Disease: A Potential Player in the Pathogenesis of the Disease., PMID:40231494
ADAMTS18 deficiency leads to abnormal brain methylation metabolism, dysregulated neuroinflammatory response, and unsound blood-brain barrier structure in mice., PMID:40227359
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt., PMID:40225588
Utility of serum and urine leucine-rich alpha-2 glycoprotein 1 (LRG1) as predictors of appendicitis and complicated appendicitis in children., PMID:40208339
LRG1, a novel serum biomarker for iMCD disease activity., PMID:40197491
Mutation of the LRG1 Rho-GAP gene is responsible for the hyper branching C-variant phenotype in the quorn mycoprotein fungus Fusarium venenatum A3/5., PMID:40128830
Leucine-rich α-2 glycoprotein 1 (LRG1) during inflammatory complications after allogeneic stem cell transplantation and CAR-T cell therapy., PMID:40118496
Metabolomics- and Proteomics-Based Disease Diagnostic Classifier Model for the Prediction and Diagnosis of Colorectal Carcinoma., PMID:40108892
Leucine-rich Alpha-2 glycoprotein could be clinically useful in active and postoperative Crohn's disease., PMID:40091130
Diagnostic and Prognostic Biomarkers of Idiopathic Normal Pressure Hydrocephalus in Cerebrospinal Fluid and Blood., PMID:40054974
Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories., PMID:40046342
PROTAC based targeted degradation of LRG1 for mitigating corneal neovascularization., PMID:39993640
Modulation of TGF-β signaling new approaches toward kidney disease and fibrosis therapy., PMID:39990662
Diagnostic accuracy and cut-off values of serum leucine-rich alpha-2 glycoprotein for Crohn's disease activity in the small bowel., PMID:39953247
LRG1-Targeted Camptothecin Nanomicelles with Simultaneous Delivery of Olaparib for Enhanced Colorectal Cancer Chemotherapy., PMID:39947227
Changes of leucine-rich alpha 2 glycoprotein could be a marker of changes of endoscopic and histologic activity of ulcerative colitis., PMID:39939376
A Role for Leucine-Rich α2-Glycoprotein in Leukocyte Trafficking and Mucosal Inflammation in Inflammatory Bowel Disease., PMID:39918378
Leucine-rich alpha-2 glycoprotein in combination with C-reactive protein for predicting endoscopic activity in Crohn's disease: a single-centre, cross-sectional study., PMID:39823192
Lead time trajectory of blood-based protein biomarkers for detection of pancreatic cancer based on repeat testing., PMID:39793753
Leucine-rich alpha-2-glycoprotein 1 deficiency suppresses ischemia-reperfusion injury-induced renal fibrosis., PMID:39779883
Diagnostic values of serum levels of α-synuclein, homocysteine and leucine-rich α2 glycoprotein for predicting cognitive impairment in Parkinson's disease., PMID:39738968
DNMT3a Deficiency Contributes to Anesthesia/Surgery-Induced Synaptic Dysfunction and Cognitive Impairment in Aged Mice., PMID:39722450
Leucine-Rich Alpha-2 Glycoprotein Is Associated With Transmural Inflammation Assessed by Intestinal Ultrasound in Patients With Crohn's Disease., PMID:39641226
Selection of anti-cytokine biologics by pretreatment levels of serum leucine-rich alpha-2 glycoprotein in patients with inflammatory bowel disease., PMID:39613813
Serum Leucine-Rich Alpha-2 Glycoprotein 1 Levels in Patients with Lipodystrophy Syndromes., PMID:39595649
Diet-enhanced LRG1 expression promotes insulin hypersecretion and ER stress in pancreatic beta cells., PMID:39589509
Effects of initial periodontal therapy on leucine-rich alpha-2 glycoprotein levels in saliva from Japanese patients with chronic periodontitis., PMID:39581585
Knockdown of Leucine-rich alpha-2-glycoprotein 1 alleviates renal ischemia-reperfusion injury by inhibiting NOX4-mediated apoptosis, inflammation, and oxidative stress., PMID:39566877
Cross-Sectional and Longitudinal Associations of Serum LRG1 with Severity and Prognosis Among Adult Community-Acquired Pneumonia Patients., PMID:39502939
Clinical Profiles of Leucine-Rich Alpha-2 Glycoprotein for Indicating Mucosal Healing in Ulcerative Colitis Patients under Administration of Molecular-Targeted Drug., PMID:39462503
Study on the activity and mechanism of herbal formula anti-infection powder (AIP) against influenza-virus-induced pneumonia through genetic susceptibility genes., PMID:39426575
Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
Novel Serum Markers that Distinguish Behcet's Disease from Idiopathic Recurrent Aphthous Stomatitis., PMID:39356129
A Strategy Involving Microporous Microneedles Integrated with CAR-TREM2-Macrophages for Scar Management by Regulating Fibrotic Microenvironment., PMID:39313983
A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone., PMID:39276915
Targeted degradation of LRG1 to attenuate renal fibrosis., PMID:39246511
Diagnostic Performance of Serum Leucine-Rich Alpha-2-Glycoprotein 1 in Pediatric Acute Appendicitis: A Prospective Validation Study., PMID:39200285
LRG1-Targeted Nintedanib Delivery for Enhanced Renal Fibrosis Mitigation., PMID:39185720
LRG1 promotes atherosclerosis by inducing macrophage M1-like polarization., PMID:39178231
Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma., PMID:39174053
For research use only. Not for human or drug use.
