Catalog No.
YHB97701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His1444-Thr1669
Predicted molecular weight
27.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02462
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen alpha-1(IV) chain, COL4A1
Investigating the Genetic Links Between Immune Cell Profiles and Bladder Cancer: A Multidisciplinary Bioinformatics Approach., PMID:40427030
A diet-driven metabolic dysfunction-associated steatohepatitis (MASH) mouse model resembles the corresponding human disease., PMID:40392411
XPD Regulates MIAT/miR-29a-3p/COL4A1 Axis to Impede Hepatocellular Carcinoma Development., PMID:40372289
Genetic aetiologies in relation to response to the ketogenic diet in 226 children with epilepsy., PMID:40290421
Altered expression of collagen gene family members and its epigenetic background in equine Sarcoids., PMID:40288239
Mas Signaling Potentiates Neutrophil Extracellular Traps Formation Induced by Endothelial Cells Derived S1P in Mice with Acute Liver Failure., PMID:40285622
A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome., PMID:40279671
METTL16/IGF2BP2 axis enhances malignant progression and DDP resistance through up-regulating COL4A1 by mediating the m6A methylation modification of LAMA4 in hepatocellular carcinoma., PMID:40251670
Deciphering the role of lncRNA-mediated ceRNA network in disuse osteoporosis: insights from bone marrow mesenchymal stem cells under simulated microgravity., PMID:40248073
Anti-Fibrotic Effect of Oleamide Identified from the Moringa oleifera Lam. Leaves via Inhibition of TGF-β1-Induced SMAD2/3 Signaling Pathway., PMID:40244247
Collagen IV of basement membranes: I. Origin and diversification of COL4 genes enabling metazoan multicellularity, evolution, and adaptation., PMID:40220996
Novel variations in the PLOD1, COL1A1, COL5A2 and COL4A1 genes related to keratoconus., PMID:40201566
Exome sequencing of a Portuguese cohort of early-onset Alzheimer's disease implicates the X-linked lysosomal gene GLA., PMID:40185916
Chitosan nanoparticles as a targeted delivery system for anti-fibrotic microRNAs for oral submucosal fibrosis treatment., PMID:40184720
Combined targeting of TCF7L1/2, PTEN, CDK6, and BCCIP by microRNA miR-29c-3p is associated with reduced invasion and proliferation of endometriotic cells., PMID:40135061
Identification of Ferroptosis- and Hypoxia-related Genes in iPSC-derived Oligodendrocyte Precursor Cells from Multiple Sclerosis Patients., PMID:40127044
Identity-by-Descent Analysis Uncovering a Founder Event in a Novel Hereditary Small Vessel Cerebral Disease., PMID:40123492
Integrative bioinformatics analysis of high-throughput sequencing and in vitro functional analysis leads to uncovering key hub genes in esophageal squamous cell carcinoma., PMID:40087784
Phenotype and surgical management of drug-resistant epilepsy in patients with COL4A1 and COL4A2 variants., PMID:40055992
A patient with pontine autosomal dominant microangiopathy and leukoencephalopathy caused by a de novo 3' untranslated region mutation of COL4A1 gene: case report and literature review., PMID:39976879
Roles of WDR12 and MRTO4 genes in colorectal cancer., PMID:39969382
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
Type IV collagen expression is regulated by Notch3-mediated Notch signaling during angiogenesis., PMID:39842335
Functional Characteristics of the Crosstalk Between Vocal Fold Fibroblasts and Macrophages-The Role of Vibration in Vocal Fold Inflammation., PMID:39799073
Fetal intracranial hemorrhage in second trimester: An ominous finding even after a normal array., PMID:39794016
Integrative Proteomics and Phosphoproteomics Profiling of Symptomatic Accessory Navicular Bone Based on Tandem Mass Tag Technology., PMID:39698044
COL4A2 -Related Disorder Presenting in Adulthood With Rhabdomyolysis., PMID:39679724
Increased spatial coupling of integrin and collagen IV in the immunoresistant clear-cell renal-cell carcinoma tumor microenvironment., PMID:39639369
A multi-omics approach identifies the key role of disorders of sphingolipid metabolism in Ang II-induced hypertensive cardiomyopathy myocardial remodeling., PMID:39638825
Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites., PMID:39580674
Multiple intracerebral hematomas during SEEG recording and intradural hemorrhage after spinal tap: A case report prompting more research on collagen IV gene mutation and oral nicotine consumption as risk factors., PMID:39579033
Genetic Insights into Therapeutic Targets for Neuromyelitis Optica Spectrum Disorders: A Mendelian Randomization Study., PMID:39565569
Integrative transcriptome analysis reveals Serpine2 promotes glomerular mesangial cell proliferation and extracellular matrix accumulation via activating ERK1/2 signalling pathway in diabetic nephropathy., PMID:39557806
Microglial activation without peripheral immune cell infiltration characterises mouse and human cerebral small vessel disease., PMID:39543785
The impact of hsa-miR-1972 on the expression of von Willebrand factor in breast cancer progression regulation., PMID:39529627
Comparative analysis of human and mouse transcriptomes during skin wound healing., PMID:39534398
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin., PMID:39522978
Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond., PMID:39508046
Podoplanin Expression in Early-Stage Colorectal Cancer-Associated Fibroblasts and Its Utility as a Diagnostic Marker for Colorectal Lesions., PMID:39451200
Single-Cell Meta-Analysis Uncovers the Pancreatic Endothelial Cell Transcriptomic Signature and Reveals a Key Role for NKX2-3 in PLVAP Expression., PMID:39445426
ASSESSMENT OF RETINAL ARTERIOLAR TORTUOSITY IN PATIENTS WITH COL4A1 OR COL4A2 MUTATIONS., PMID:39405554
Changes of collagen content in lung tissues of plateau yak and its mechanism of adaptation to hypoxia., PMID:39372716
Plasma Proteomic Insights for Identification of Novel Predictors and Potential Drug Targets in Atrial Fibrillation: A Prospective Cohort Study and Mendelian Randomization Analysis., PMID:39355913
Identification of a novel intronic variant in COL4A2 gene associated with fetal severe cerebral encephalomalacia and subdural hemorrhage., PMID:39350129
Integrated ubiquitomics characterization of hepatocellular carcinomas., PMID:39348425
Whole-transcriptome analyses of ovine lung microvascular endothelial cells infected with bluetongue virus., PMID:39334220
Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage., PMID:39216230
In Vitro Investigation of the Anti-Fibrotic Effects of 1-Phenyl-2-Pentanol, Identified from Moringa oleifera Lam., on Hepatic Stellate Cells., PMID:39201682
Skeletal pathology in mouse models of Gould syndrome is partially alleviated by genetically reducing TGFβ signaling., PMID:39097038
Aryl Hydrocarbon Receptor Activation in Pulmonary Alveolar Epithelial Cells Limits Inflammation and Preserves Lung Epithelial Cell Integrity., PMID:39033086
For research use only. Not for human or drug use.
