Catalog No.
YHA46602
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu291-Ala486
Predicted molecular weight
24.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15240
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NERP-2, NERP-1, VGF, Neurosecretory protein VGF
Identification of different lung adenocarcinoma subtypes in combination with antidiuretic hormone-related genes and creation of an associated index to predict prognosis and guide immunotherapy., PMID:40412340
Defining lung adenocarcinoma subtypes with glucocorticoid-related genes and constructing a prognostic index for immunotherapy guidance., PMID:40400930
Discovery of Proteoforms Associated With Alzheimer's Disease Through Quantitative Top-Down Proteomics., PMID:40334744
Sleep quality in late pregnancy is associated with maternal mental health in the early postpartum period., PMID:40319760
VGF and Its Derived Peptides in Amyotrophic Lateral Sclerosis., PMID:40309800
Specific expression and common potential therapeutic drugs in different brain regions of major depressive disorder patients: bioinformatics analysis., PMID:40286923
Identification of gene signatures associated with lactation for predicting prognosis and treatment response in breast cancer patients through machine learning., PMID:40253524
Overexpression of OTX2 in human neural cells links depression risk genes., PMID:40216752
Cerebrospinal fluid VGF is associated with the onset and progression of Alzheimer's disease., PMID:40095667
Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies., PMID:40082954
VGF and the VGF-derived peptide AQEE30 stimulate osteoblastic bone formation through the C3a receptor., PMID:40082672
Changes in the Proteomic Profile After Audiogenic Kindling in the Inferior Colliculus of the GASH/Sal Model of Epilepsy., PMID:40076950
Blockade of glucagon receptor induces α-cell hypersecretion by hyperaminoacidemia in mice., PMID:40075066
A novel oncolytic vaccinia virus with multiple gene modifications involved in viral replication and maturation increases safety for intravenous administration while maintaining proliferative potential in cancer cells., PMID:40048445
Global emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae driven by an IncFIIK34 KPC-2 plasmid., PMID:40024096
Hypoxia-Induced VGF Promotes Cell Migration and Invasion in Prostate Cancer via the PI3K/Akt Axis., PMID:40018933
Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia., PMID:39966757
NERP-1 modifications in amyotrophic lateral sclerosis., PMID:39933412
Histone Lysine Crotonylation Associated Epigenetic Mechanism Dynamically Regulates Prenatal Stress Induced Anxiety-Related Behaviour in Adolescent Offspring., PMID:39842413
Vaccinia growth factor-dependent modulation of the mTORC1-CAD axis upon nutrient restriction., PMID:39817770
Estrogen-Regulated Lateral Septal Kisspeptin Neurons Abundantly Project to GnRH Neurons and the Hypothalamic Supramammillary Nucleus., PMID:39746822
A novel immune-related gene prognostic signature combining immune cell infiltration and immune checkpoint for glioblastoma patients., PMID:39697704
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds., PMID:39668376
Changes in hippocampal volume, 5-HT4 receptor binding, and verbal memory over the course of antidepressant treatment in major depressive disorder., PMID:39616866
Involvement of the VGF/BDNF axis in the neuropathology of Alzheimer's disease and its potential role in diagnosis and treatment., PMID:39566031
Stimulation of neutral lipid synthesis via viral growth factor signaling and ATP citrate lyase during vaccinia virus infection., PMID:39475274
Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort., PMID:39471050
Neuropeptide Precursor VGF Promotes Liver Metastatic Colonization of Gαq Mutant Uveal Melanoma by Facilitating Tumor Microenvironment via Paracrine Loops., PMID:39422674
Growth Differentiation Factor 15 during pregnancy and postpartum as captured in blood, cerebrospinal fluid and placenta: A cohort study on associations with maternal mental health., PMID:39418693
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF., PMID:39403102
DNA methylation of serotonin genes as predictive biomarkers of antidepressant treatment response., PMID:39368538
Proteomic insights into early-stage Alzheimer's disease: Identifying key neuronal proteins impacted by amyloid beta oligomers in an in vitro model., PMID:39362622
Aging alters the expression of trophic factors and tight junction proteins in the mouse choroid plexus., PMID:39334352
(2R, 6R)-hydroxynorketamine ameliorates PTSD-like behaviors during the reconsolidation phase of fear memory in rats by modulating the VGF/BDNF/GluA1 signaling pathway in the hippocampus., PMID:39326635
Proteogenomic signature of risk of Alzheimer's disease and related dementia risk in individuals with a history of major depression disorder., PMID:39314945
Lower Plasma Levels of Selective VGF (Non-Acronymic) Peptides in Bipolar Disorder: Comparative Analysis Reveals Distinct Patterns across Mood Disorders and Healthy Controls., PMID:39245034
The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis., PMID:39145444
An engineered prodrug selectively suppresses β-lactam resistant bacteria in a mixed microbial setting., PMID:39131315
FGL2/FcγRIIB Signalling Mediates Arterial Shear Stress-Mediated Endothelial Cell Apoptosis: Implications for Coronary Artery Bypass Vein Graft Pathogenesis., PMID:39062880
Eleven neurology-related proteins measured in serum are positively correlated to the severity of diabetic neuropathy., PMID:39048581
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice., PMID:39006222
Role of vaccinia virus growth factor in stimulating the mTORC1-CAD axis of the de novo pyrimidine pathway under different nutritional cues., PMID:39005450
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system., PMID:38985854
Changes in expression of VGF, SPECC1L, HLA-DRA and RANBP3L act with APOE E4 to alter risk for late onset Alzheimer's disease., PMID:38942763
Multisensory Fusion Training and 7, 8-Dihydroxyflavone Improve Amyloid-β-Induced Cognitive Impairment, Anxiety, and Depression-Like Behavior in Mice Through Multiple Mechanisms., PMID:38883414
CSF neurosecretory proteins VGF and neuroserpin in patients with Alzheimer's and Lewy body diseases., PMID:38850771
Integrated transcriptomic analysis reveals immune signatures distinguishing persistent versus resolving outcomes in MRSA bacteremia., PMID:38846955
Integrin αVβ1-activated PYK2 promotes the progression of non-small-cell lung cancer via the STAT3-VGF axis., PMID:38844957
BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia., PMID:38829513
Identification of Candidate Protein Biomarkers Associated with Domoic Acid Toxicosis in Cerebrospinal Fluid of California Sea Lions (Zalophus californianus)., PMID:38807289
For research use only. Not for human or drug use.
