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Recombinant Human HLA-DRB1 Protein, N-His

Catalog #:   YHB96801 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P01911
Protein length: Gly30-Ser266
Overview

Catalog No.

YHB96801

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Gly30-Ser266

Predicted molecular weight

29.36 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P01911

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human HLA-DRB1 protein
References

Influence of HLA Class I and II Polymorphisms on COVID-19 Severity in a South Brazilian Population., PMID:40508150

Acute Lymphoblastic Leukemia and Associated HLA-A, B, DRB1, and DQB1 Molecules: A Moroccan Pediatric Case-Control Study., PMID:40508101

Characterization of HLA-A/HLA-B/HLA-C/HLA-DRB1 Haplotypes in Romanian Stem Cell Donors Through High-Resolution Next-Generation Sequencing., PMID:40508057

Association of Functional Gene Variants in DYSF-ZNF638, MTSS1 and Ferroptosis-Related Genes with Multiple Sclerosis Severity and Target Gene Expression., PMID:40507797

T cell and autoantibody recognition of nucleus-associated islet autoantigens in individuals with type 1 diabetes., PMID:40490584

Genomic Full-Length Sequence of the HLA-DRB1*04:90 Allele Was Identified by PacBio Sequencing., PMID:40474756

GWAS identifies genetic loci for antibody response to SARS-CoV-2 vaccines in patients with systemic autoimmune diseases and healthy individuals., PMID:40463545

Etiologic Determinants and Characteristics of Diabetes in Haitian Youth (EDDHY Study)., PMID:40458319

Cross-phenotype genome-wide association study supports shared genetic etiology between skin and gastrointestinal tract diseases., PMID:40441863

Genomic Full-Length Sequence of the HLA-DRB1*14:84 Allele, Identified by PacBio Sequencing., PMID:40434117

HLA-DRB1 allele distribution in Chilean population: insights into rheumatoid arthritis susceptibility and protection., PMID:40433380

Case Study: Genetic and In Silico Analysis of Familial Pancreatitis., PMID:40428425

A Cross-Tissue Transcriptome-Wide Association Study Reveals Novel Susceptibility Genes for Diabetic Kidney Disease in the FinnGen Cohort., PMID:40427057

HLA-DRB1 alleles and salivary Streptococcus mutans colonization in a group of Swedish children., PMID:40420122

Overexpression of hsa-HLA-DRB1 may delay diabetic wound healing and angiogenesis by regulating miRNA_12118 and FLT-1., PMID:40419622

Clinical, genetic, and proteomic characteristics of type 2 diabetes complicated with exogenous insulin antibody syndrome: a case-control study., PMID:40404055

Association Between HLA-DRB1 Serotype and HLA-DQB1 Allele Mismatches and Acute Rejection in Kidney Transplantation., PMID:40400399

Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunction., PMID:40391216

Repeated HLA-DRB1 and HLA-DQB1 Mismatches Without Preformed DSA Affect Graft Survival, Rejection and DSA Development: A Multicenter Analysis., PMID:40387242

Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta., PMID:40372913

HLA Polymorphisms and COVID-19 Susceptibility and Severity: Insights From an Iranian Patients Cohort., PMID:40366340

Identification of Five Novel HLA-DRB1 Alleles., PMID:40364540

[Identification of a case with novel HLA-DRB1*12:106 allele]., PMID:40350392

Identification of the Novel HLA-DRB1*07:60:02 Allele by Next-Generation Sequencing., PMID:40343381

Characterisation of the Novel HLA-DRB1*13:369 Allele Using Next-Generation Sequencing., PMID:40342206

Host Genetic Factors in Q Fever Susceptibility., PMID:40333225

Genomic Full-Length Sequence of the HLA-DRB1*03:19 Allele Was Identified in a Chinese Bone Marrow Donor by PacBio Sequencing., PMID:40309971

Two New Alleles, HLA-B*40:06:01:20 and HLA-DRB1*09:61N, Detected in a Spanish Bone Marrow Donor., PMID:40304196

Genomic Full-Length Sequence of the HLA-DRB1*13:97:01 Allele Was Identified by PacBio Sequencing., PMID:40304174

High-Resolution Sequencing Identifies Six Novel HLA-DRB1 Alleles., PMID:40304128

Identification of the Novel HLA-DRB1*08:03:16 Allele by Next-Generation Sequencing., PMID:40301003

HLA Polymorphisms Linked to the Severity and Extent of Periodontitis in Patients with Type 1 Diabetes from a Brazilian Mixed Population., PMID:40283738

[Multiple sclerosis and the Epstein-Barr Virus: Current perspectives on their pathogenic mechanisms]., PMID:40279402

Computational Immunogenetic Analysis of Botulinum Toxin A Immunogenicity and HLA Gene Haplotypes: New Insights., PMID:40278680

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB1*15:01/DQB1*06:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A., PMID:40270541

Cost-Effective and Highly Scalable Typing of HLA Classes I and II Genes of up to 96 Individuals Using Nanopore Sequencing., PMID:40270210

Evaluating the Antigen and Eplet Accuracy of DQA1 Imputations With the HaploSFHI Two-Field HLA Typing Inference Tool., PMID:40269614

Paediatric autoimmune uveitis is associated with intraocular antibodies against Epstein-Barr virus Nuclear Antigen 1 (EBNA-1)., PMID:40239467

HLA Class I and II allelic diversity among Ecuadorian transplant candidates: A comprehensive retrospective analysis., PMID:40239304

Human leukocyte antigen (HLA) class I and II genetic relationships with brain imaging measures: A systematic review and meta-analysis., PMID:40222562

Investigation of an outbreak of novel hepatitis of unknown aetiology in children and adolescents, Ireland, 2021 to 2023., PMID:40211974

The New HLA-DRB1*11:343 Allele Encoding for A Distinctive Peptide-Binding Domain., PMID:40205942

A Potential Link Between HLA-DRB1/DQB1 Alleles and Response to Treatment in Rheumatoid Arthritis Patients., PMID:40195278

Characterisation of the Novel HLA-DRB1*14:268 Allele by Sequencing-Based Typing., PMID:40194979

Allele and Haplotype Frequencies of 17 HLA-Related Loci in Shenzhen Chinese Population by Next-Generation Sequencing., PMID:40193066

Stratifying Multiple Sclerosis Susceptibility Risk: The Role of HLA-E*01 and Infectious Mononucleosis in a Population Cohort., PMID:40192262

HLA class II-restricted T cell epitopes in public neoantigens of ESR1 and PIK3CA in breast cancer., PMID:40186192

Shared Genetic Basis, Biological Function and Causal Relationship Between Sleep Traits and Hypothyroidism: Evidence from a Comprehensive Genetic Analysis., PMID:40183266

An Investigative Study of LGALSL and HLA-DRB1 as Prognostic Biomarkers and Therapeutic Targets in Chronic Hepatitis B Patients With Persistent HBV DNA Viremia Under Entecavir Treatment., PMID:40167905

Anti-GAD antibody-negative, anti-IA2 antibody-positive slowly progressive insulin-dependent diabetes mellitus and Graves' disease preceded by childhood-onset minimal change nephrotic syndrome: a case report., PMID:40166451

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human HLA-DRB1 Protein, N-His [YHB96801]
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