Catalog No.
YHB94601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys24-Glu188
Predicted molecular weight
21.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01563
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interferon alpha-2, IFNA2C, IFNA2, IFN-alpha-2, LeIF A, IFNA2A, IFNA2B, Interferon alpha-A
Recombinant protein synthesis and isolation of human interferon alpha-2 in cyanobacteria., PMID:38583672
The effects of TGF-β1 and IFN-α2b on decorin, decorin isoforms and type I collagen in hypertrophic scar dermal fibroblasts., PMID:38243615
More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients., PMID:38077399
A Simplified Process for Purification and Refolding of Recombinant Human Interferon-α2b., PMID:34861751
Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome., PMID:33845874
Detailed structure of mouse interferon α2 and its interaction with Sortilin., PMID:33769476
Tumor microenvironment immune subtypes for classification of novel clear cell renal cell carcinoma profiles with prognostic and therapeutic implications., PMID:33725966
Comparative Cell Surface Proteomic Analysis of the Primary Human T Cell and Monocyte Responses to Type I Interferon., PMID:33628210
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine., PMID:33544838
[Interferon-regulating activity of the celagrip antiviral drug and its influence on formation of reactive oxygen species and expression of innate immunity genes in the follicular lymphoma patients]., PMID:33533212
Pharmacokinetics Versus In Vitro Antiproliferative Potency to Design a Novel Hyperglycosylated hIFN-α2 Biobetter., PMID:33443683
Type-I Interferon assessment in 45 minutes using the FilmArray® PCR platform in SARS-CoV-2 and other viral infections., PMID:33314090
Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression., PMID:33304351
Serum interferon levels associated with the disease activity in women with overt Graves' disease., PMID:33121876
Early type I IFN blockade improves the efficacy of viral vaccines., PMID:32820330
Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ Signaling., PMID:32333814
Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption., PMID:32017709
The pattern of antiviral protein expression induced by interferon λ1 in peripheral blood mononuclear cells of patients with chronic hepatitis C virus infection., PMID:31927635
Effects of monocyte chemoattractant protein-1, macrophage inflammatory protein-1α, and interferon-α2a on P450 enzymes in human hepatocytes in vitro., PMID:31857909
High yield expression, characterization, and biological activity of IFNα2-Tα1 fusion protein., PMID:31718419
Biologic therapy for Behçet's uveitis: a systematic review., PMID:31676596
Absence of mutations in the human interferon alpha-2b gene in workers chronically exposed to ionising radiation., PMID:31246567
Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways., PMID:31127086
A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product-related impurity removal., PMID:31081177
Secreting oviduct epithelial cells of Coturnix coturnix japonica (QOEC) and changes to their proteome after nonviral transfection., PMID:30854717
Bevacizumab plus IFN-alpha-2a in First-line Treatment of Patients With Advanced or Metastatic Renal Cell Carcinoma: A Prospective German Non-interventional Study., PMID:30711970
Rituximab, interferon-alfa-2b and dose dense CVP is highly efficient in patients with FLIPI ≥ 2 follicular lymphoma. Final results of the LNH-PRO-05 study., PMID:30656671
A Child with Early-Onset Gorham-Stout Disease Complicated by Chylothorax: Near-Complete Regression of Bone Lesions with Interferon and Bisphosphonate Treatment., PMID:30630178
Interferon-alpha 2 but not Interferon-gamma serum levels are associated with intramuscular fat in obese patients with nonalcoholic fatty liver disease., PMID:30602382
A chicken bioreactor for efficient production of functional cytokines., PMID:30594166
Interferon-associated therapies toward HIV control: The back and forth., PMID:29555233
Interferon α subtypes in HIV infection., PMID:29475588
Dysregulation of miR-155-5p and miR-200-3p and the Anti-Non-Bilayer Phospholipid Arrangement Antibodies Favor the Development of Lupus in Three Novel Murine Lupus Models., PMID:29349090
Binding of cholera toxin B subunit to intestinal epithelial cells., PMID:29262310
Determination of recombinant Interferon-α2 in E. coli periplasmic extracts by reversed-phase high-performance liquid chromatography., PMID:29179059
An A/U-Rich Enhancer Region Is Required for High-Level Protein Secretion through the HlyA Type I Secretion System., PMID:29030442
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor., PMID:28958921
Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells., PMID:28615266
Elevated hepatic lipid and interferon stimulated gene expression in HCV GT3 patients relative to non-alcoholic steatohepatitis., PMID:27193023
Gene therapy with plasmids encoding IFN-β or IFN-α14 confers long-term resistance to HIV-1 in humanized mice., PMID:27729616
[Anti-tumor effects of 13-cis-retinoic acid combined with interferon α-2b in animal model of mantle cell lymphoma]., PMID:27719722
Binding of Synthetic LKEKK Peptide to Human T-Lymphocytes., PMID:27677554
Integrity of a HPV11 infection cell model and identification of (-)-Epigallocatechin-3-gallate as a potential HPV11 inhibitor., PMID:27175598
Biased expression, under the control of single promoter, of human interferon α-2b and Escherichia coli methionine amino peptidase genes in E. coli, irrespective of their distance from the promoter., PMID:27087087
Topical Interferon Alpha-2b for Diffuse Conjunctival Primary Acquired Melanosis with Atypia., PMID:26765558
Melanoma Patient-Reported Quality of Life Outcomes Following Sentinel Lymph Node Biopsy, Completion Lymphadenectomy, and Adjuvant Interferon: Results from the Sunbelt Melanoma Trial., PMID:26744107
Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain., PMID:26679999
Increased binding of circulating systemic lupus erythematosus autoantibodies to recombinant interferon alpha 2b., PMID:26547367
Endotoxin tolerance in monocytes can be mitigated by α2-interferon., PMID:26206900
IFNA2: The prototypic human alpha interferon., PMID:25982860
For research use only. Not for human or drug use.
