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InVivoMAb Anti-aPC/Activated protein C Antibody (T46J23)

Catalog #:   VHC05903 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, Neutralization
Accession: P04070
Overview

Catalog No.

VHC05903

Species reactivity

Human, Mouse, Dog

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA, PROC

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04070

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

T46J23

Data Image
References

Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway., PMID:40415368

USP25-driven KIFC1 regulates MYCBP expression and promotes the progression of cervical cancer., PMID:40379626

Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain., PMID:40377985

Esculetin Inhibits Fat Accumulation Through Insulin/Insulin-like Growth Factor- and AMP-Activated Protein Kinase-Dependent Pathways in Caenorhabditis elegans., PMID:40362874

Matrine Inhibits High-Glucose-Diet-Induced Fat Accumulation and Aβ-Mediated Lipid Metabolic Disorder via AAK-2/NHR-49 Pathway in Caenorhabditis elegans., PMID:40338235

Unlocking the Potential of Curcumae Rhizoma Aqueous Extract in Stress Resistance and Extending Lifespan in Caenorhabditis elegans., PMID:40333562

Beyond prothrombin time and activated partial thromboplastin time: coagulation in vivo-an illustrated review., PMID:40319459

SQST-1/p62-regulated SKN-1/Nrf mediates a phagocytic stress response via transcriptional activation of lyst-1/LYST., PMID:40315422

Xanthatin induces apoptosis through ROS-mediated c-FLIP inhibition in human retinoblastoma cells., PMID:40309730

Design, synthesis and in vitro and in vivo biological evaluation of matrine derivatives as efficient anticancer agents with the characteristics of endoplasmic reticulum stress induction and apoptosis activation., PMID:40273706

A novel peptide derived from Haematococcus pluvialis residue balanced lipid metabolism through NHR-49/PPARα and AAK-2/AMPK pathways in Caenorhabditis elegans., PMID:40249062

Targeting USP11 counteracts SFTPCI73T -associated interstitial lung disease in hiPSCs-derived alveolar organoids and in vivo models., PMID:40225577

Amelioration of Isoproterenol-Induced Myocardial Infarction by the Phytochemical Koenigicine via Modulation of NF-κB/HO-1/NQO-1 Pathways: An In Vivo Analysis., PMID:40192543

Heat tolerance and genetic adaptations in Caenorhabditis briggsae: insights from comparative studies with Caenorhabditis elegans., PMID:40172097

cMyBP-C in hypertrophic cardiomyopathy: gene therapy and small-molecule innovations., PMID:40134985

GM-CSF-mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus., PMID:40117345

Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals., PMID:40108168

Snake Venom-Inspired Novel Peptides Protect Caenorhabditis elegans against Paraquat-Induced Parkinson's Pathology., PMID:40096006

Unraveling the Dual Role of circ-CBLB and ETS-1 in Rheumatoid Arthritis: Biomarkers and Therapeutic Targets., PMID:40095292

In vivo neuroprotection in ischemic stroke by activated protein C requires β-arrestin 2., PMID:40093572

Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter., PMID:40089636

Asymmetry in centrosome maturation revealed through AIR-1 dynamics in the early Caenorhabditis elegans embryo., PMID:40082489

UNC-6/Netrin promotes both adhesion and directed growth within a single axon., PMID:40052533

Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizations., PMID:40010690

Recombinant factor VIIa: new insights into the mechanism of action through product innovation., PMID:39990097

The anti-aging and anti-Alzheimer's disease potential of kinsenoside prepared from Anoectochilus roxburghii., PMID:39938659

Protection of Mice Vaccinated with a New B Cell and T Cell Epitopes Cocktail from Staphylococcus aureus Challenge in Skin Infection Model., PMID:39922982

Lycium ruthenicum Murray exosome-like nanovesicles alleviated Alzheimer's disease-like symptoms induced by Aβ protein in transgenic Caenorhabditis elegans through the DAF-16 pathway., PMID:39922347

High-resolution analysis of human centromeric chromatin., PMID:39848706

Endothelium Modulates the Prothrombotic Phenotype of Factor V Leiden: Evidence From an Ex Vivo Model., PMID:39846164

CRMP/UNC-33 maintains neuronal microtubule arrays by promoting individual microtubule rescue., PMID:39842439

Short- and long-range roles of UNC-6/Netrin in dorsal-ventral axon guidance in vivo in Caenorhabditis elegans., PMID:39823521

LHPP-P38 MAPK/ERK-ETS1 Axis Negative Feedback Signaling Restrains Progression in Breast Cancer., PMID:39789996

The Astragalus Membranaceus Herb Attenuates Leukemia by Inhibiting the FLI1 Oncogene and Enhancing Anti-Tumor Immunity., PMID:39769192

A higher order PUF complex is central to regulation of C. elegans germline stem cells., PMID:39747099

Thrombosis in Children: A Retrospective Study from a Single-center Database., PMID:39740908

Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells., PMID:39715269

Loss of protein C vs protein S results in discrepant thrombotic phenotypes., PMID:39657127

Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo., PMID:39673181

RFC4 confers radioresistance of esophagus squamous cell carcinoma through regulating DNA damage response., PMID:39672175

A fluorescent protein C-terminal fusion knock-in is functional with TRPA1 but not TRPC5., PMID:39662746

CRISPR-Cas9 screening identifies the role of FER as a tumor suppressor., PMID:39648412

Novel affibody molecules targeting the AXL extracellular structural domain for molecular imaging and targeted therapy of gastric cancer., PMID:39644434

Pseudogene KRT17P3 Promotes NSCLC Progression Through Mir-338-3p/USP7/C-Myc., PMID:39626929

Anesthetic-like effects of ketamine in C. elegans., PMID:39561954

Surfactant Protein-C Regulates Alveolar Type 2 Epithelial Cell Lineages via the CD74 Receptor., PMID:39553282

Vericiguat enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction through microRNA-1180-3p/ETS1 pathway., PMID:39551415

Polysaccharides from Ziziphus jujuba prolong lifespan and attenuate oxidative stress in Caenorhabditis elegans via DAF-16 and SKN-1., PMID:39528176

ETS1 promotes cisplatin resistance of NSCLC cells by promoting GRP78 transcription., PMID:39521757

Cure of Congenital Purpura Fulminans via Expression of Engineered Protein C Through Neonatal Genome Editing in Mice., PMID:39508105

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-aPC/Activated protein C Antibody (T46J23) [VHC05903]
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