Catalog No.
VHC95201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
CD324, Uvomorulin, Epithelial cadherin, E-cadherin, CDHE, CAM 120/80, UVO, CDH1, Cadherin-1, CDH11, OSF-4, Osteoblast cadherin, Cadherin-11, OB-cadherin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P12830, P55287
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
23C6
Development and validation of a multiple myeloma diagnostic model based on systemic lupus erythematosus-associated genes and identification of specific genes., PMID:40382732
[Innovations in the Current Guideline on Gastric Carcinoma and Outlook for the Future]., PMID:40199374
The feasible role of soluble E‑cadherin in spheroidogenesis of HCT116 colorectal cancer cells, a candidate biomarker for liquid biopsy., PMID:40182609
Pairwise analysis of plasma cell-free DNA before and after palliative second-line paclitaxel plus ramucirumab treatment in patients with metastatic gastric cancer., PMID:40148708
Case report: Chemotherapy plus sintilimab for the treatment of gastroesophageal junction hepatoid adenocarcinoma with liver metastasis: a case study with literature review., PMID:39931054
Aberrant E-cadherin Expression in Lobular Carcinoma In Situ: A Comprehensive Immunohistochemical Evaluation of N-terminal, Extracellular, and C-terminal E-cadherin Domains., PMID:39807823
IL-8 promotes lens capsular residual cells migration by down-regulates expression of E-cadherin and ZO-1 via the CXCR1/2-NF-κB-RhoA signal pathway., PMID:39244903
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
Advantages of automated immunostain analyses for complex membranous immunostains: An exemplar investigating loss of E-cadherin expression in colorectal cancer., PMID:39032383
E-Cadherin Mutational Landscape and Outcomes in Breast Invasive Lobular Carcinoma., PMID:39025406
E-Cadherin Induces Serine Synthesis to Support Progression and Metastasis of Breast Cancer., PMID:38959339
A phase II study of cabozantinib and pembrolizumab in advanced gastric/gastroesophageal adenocarcinomas resistant or refractory to immune checkpoint inhibitors., PMID:38823034
Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer., PMID:38717153
Targeting tumorous Circ-E-Cadherinencoded C-E-Cad inhibits the recruitment and function of breast cancer-associated myeloid-derived suppressor cells., PMID:38704109
Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium., PMID:38641322
Targeting PI3K/AKT/mTOR and MAPK Signaling Pathways in Gastric Cancer., PMID:38339127
Dulaglutide as a demethylating agent to improve the outcome of breast cancer., PMID:38174426
The genomic and immune landscapes of gastric cancer and their correlations with HER2 amplification and PD-L1 expression., PMID:38050871
Soluble E-cadherin participates in BLM-induced pulmonary fibrosis by promoting EMT and lung fibroblast migration., PMID:37792543
Concurrent predictors of an immune responsive tumor microenvironment within tumor mutational burden-high breast cancer., PMID:37637072
Breast Cancer Mutations HER2V777L and PIK3CAH1047R Activate the p21-CDK4/6-Cyclin D1 Axis to Drive Tumorigenesis and Drug Resistance., PMID:37272756
Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy., PMID:37202799
Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer., PMID:36757813
Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody., PMID:36256815
Effects of active immunization against a 13-amino acid receptor-binding epitope of FSHβ on fertility regulation in female mice., PMID:35772190
Genomic Profiling and Response to Immune Checkpoint Inhibition plus Tyrosine Kinase Inhibition in FH-Deficient Renal Cell Carcinoma., PMID:35715365
Immunohistochemical expression of E-cadherin, N-cadherin and Snail/slug in ameloblastoma., PMID:35659530
Muscle Transcriptomics Shows Overexpression of Cadherin 1 in Inclusion Body Myositis., PMID:35064929
Neutrophil extracellular traps drive epithelial-mesenchymal transition of human colon cancer., PMID:34939675
Comparison of Fixation Methods for the Detection of Claudin 1 and E-Cadherin in Breast Cancer Cell Lines by Immunofluorescence., PMID:34715746
Expression of N-Terminal-Deficient E-Cadherin Protein in Invasive Lobular Carcinoma of the Breast., PMID:34653059
E-Cadherin restricts mast cell degranulation in mice., PMID:34606636
Multiplexed DNA-Directed Patterning of Antibodies for Applications in Cell Subpopulation Analysis., PMID:34546726
E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors., PMID:34090526
2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology., PMID:34007277
Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin., PMID:33929593
Highly expressed Claudin18.2 as a potential therapeutic target in advanced gastric signet-ring cell carcinoma (SRCC)., PMID:33457012
"Switch of E-Cadherin to N-Cadherin expression in different molecular subtypes of breast invasive duct carcinomas and its correlation with clinicopathological features"., PMID:33433407
RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility., PMID:33260366
Hereditary diffuse gastric cancer therapeutic roadmap: current and novel approaches in a nutshell., PMID:33193828
Antigen-agnostic microfluidics-based circulating tumor cell enrichment and downstream molecular characterization., PMID:33095819
Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa., PMID:33066747
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2., PMID:32830536
Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt's B cell lymphoma., PMID:32782434
A novel immunohistochemical scoring system reveals associations of C-terminal MET, ectodomain shedding, and loss of E-cadherin with poor prognosis in oral squamous cell carcinoma., PMID:32702402
Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding., PMID:32476131
[Hereditary breast carcinomas pathologist's perspective]., PMID:32241645
Enhancement of aberrantly modified integrin‑mediated cell motility in multicellular tumor spheroids., PMID:32236635
BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition., PMID:31919242
Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion., PMID:31700162
For research use only. Not for human or drug use.
