Catalog No.
YHN54901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala186
Predicted molecular weight
23.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96EY8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MMAB, Methylmalonic aciduria type B protein, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase, Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase
AI-assisted multi-OMICS analysis reveals new markers for the prediction of AD., PMID:40441366
Integrative genetic analysis to decode the causal effect of air pollution on accelerated aging., PMID:40205593
Genetic insights into the role of mitochondria-related genes in mental disorders: An integrative multi-omics analysis., PMID:40180044
Multi-omics data integration reveals novel genes related to autoimmune hypothyroidism in the brain: A molecular basis for the brain-thyroid axis., PMID:39736412
Isolated methylmalonic acidemia in Mexico: Genotypic spectrum, report of two novel MMUT variants and a possible synergistic heterozygosity effect., PMID:39494389
Pathologic Substrates of Structural Brain Network Resilience and Topology in Parkinson Disease Decedents., PMID:39042844
A Noble Metal Substitution Leads to B12 Cofactor Mimicry by a Rhodibalamin., PMID:39012171
Coordination Chemistry Controls Coenzyme B12 Synthesis by Human Adenosine Triphosphate:Cob(I)alamin Adenosyltransferase., PMID:37526260
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair., PMID:37468522
Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach., PMID:37248539
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair., PMID:36993209
Single cell sequencing revealed the mechanism of PD-1 resistance affected by the expression profile of peripheral blood immune cells in ESCC., PMID:36466860
Spatiotemporal Control of Vascular CaV1.2 by α1C S1928 Phosphorylation., PMID:36345826
Transcriptional targets of amyotrophic lateral sclerosis/frontotemporal dementia protein TDP-43 - meta-analysis and interactive graphical database., PMID:35946434
[Differential diagnosis of a Chinese pedigree with methylmalonic acidemia by next-generation sequencing]., PMID:35810423
Early cardiomyopathy without severe metabolic dysregulation in a patient with cblB-type methylmalonic acidemia., PMID:35712814
SMAD4 Controls Cancer Cell Metabolism by Regulating Methylmalonic Aciduria Cobalamin Deficiency (cbl) B Type., PMID:35680374
The human B12 trafficking chaperones: CblA, ATR, CblC and CblD., PMID:35589192
Hepatocyte-like cells differentiated from methylmalonic aciduria cblB type induced pluripotent stem cells: A platform for the evaluation of pharmacochaperoning., PMID:35569737
Comparison of Antibodies to Detect Uroplakin in Urothelial Carcinomas., PMID:35510771
Genetic testing is necessary for correct diagnosis and treatment in patients with isolated methylmalonic aciduria: a case report., PMID:34915869
A tale of two multi-focal therapies for glioblastoma: An antibody targeting ELTD1 and nitrone-based OKN-007., PMID:34910361
Spectrum and characterization of bi-allelic variants in MMAB causing cblB-type methylmalonic aciduria., PMID:34796408
MMAB promotes negative feedback control of cholesterol homeostasis., PMID:34750386
Clinical and molecular findings in 37 Turkish patients with isolated methylmalonic acidemia., PMID:33453710
Quantile-Dependent Expressivity and Gene-Lifestyle Interactions Involving High-Density Lipoprotein Cholesterol., PMID:33296900
A Murine Monoclonal Antibody With Potent Neutralization Ability Against Human Adenovirus 7., PMID:31867291
[Clinical and variant analysis of 15 patients with methylmalonic acidemia]., PMID:31813137
A genetic epidemiological study in British adults and older adults shows a high heritability of the combined indicator of vitamin B12 status (cB12) and connects B12 status with utilization of mitochondrial substrates and energy metabolism., PMID:31203192
Rabbit monoclonal E-cadherin antibody: A cost-effective alternative to mouse monoclonal antibody in distinguishing ductal carcinoma in situ from lobular carcinoma in situ., PMID:31165568
Mutation analysis of genes related to methylmalonic acidemia: identification of eight novel mutations., PMID:30712249
Regulation of IAA Biosynthesis in Azospirillum brasilense Under Environmental Stress Conditions., PMID:29980814
[Heterogeneous phenotypes, genotypes, treatment and prevention of 1 003 patients with methylmalonic acidemia in the mainland of China]., PMID:29886603
Generation and characterization of two human iPSC lines from patients with methylmalonic acidemia cblB type., PMID:29660608
MMAB, a novel candidate gene to be screened in the molecular diagnosis of Mevalonate Kinase Deficiency., PMID:29234874
New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type., PMID:29197662
Increased MMAB level in mitochondria as a novel biomarker of hepatotoxicity induced by Efavirenz., PMID:29190729
Production and Characterization of F(Ab')2 Fragments Obtained by Enzymatic Digestion from Murine Anti-MRSA PBP2a Monoclonal Antibodies., PMID:29082478
Protein destabilization and loss of protein-protein interaction are fundamental mechanisms in cblA-type methylmalonic aciduria., PMID:28497574
Mitigation of Pre-existing Antibodies to a Biotherapeutic in Non-clinical Species When Establishing Anti-drug Antibody Assay Cutpoint., PMID:27873117
Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population., PMID:27716295
Lessons in biology from patients with inherited disorders of vitamin B12 and folate metabolism., PMID:27163846
[Mutation screening and prenatal diagnosis of methylmalonic academia in a Chinese pedigree by Ion Torrent semiconductor sequencing]., PMID:27060311
[Identification of two novel mutations of MUT gene in a Chinese family affected with isolated methylmalonic acidemia]., PMID:27060300
Analysis of Novel Mutations and Methylmalonyl-CoA Mutase Levels in Thai Patients with Isolated Methylmalonic Acidemia., PMID:26370686
[A Chinese boy with methylmalonic aciduria cblB type and a novel mutation in the MMAB gene]., PMID:25760844
A novel monoclonal antibody SMab-2 recognizes endogenous IDH2-R172S of chondrosarcoma., PMID:25753205
A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans., PMID:25161880
For research use only. Not for human or drug use.
