Catalog No.
YHB91801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln24-Ile92
Predicted molecular weight
10.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01148
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GRH, LHRH, Progonadoliberin I, Gonadoliberin I, Luliberin I, GnRH-associated peptide I, GnRH-I, Gonadotropin-releasing hormone I, Gonadorelin, Progonadoliberin-1, GNRH1, LH-RH I, GNRH, Luteinizing hormone-releasing hormone I
Prenatal genistein exposure in rats affects pubertal onset and serum reproductive hormone levels in male offsprings via the hypothalamic-pituitary-gonadal axis., PMID:40320066
Exploring the impact of chia seeds and matcha green tea on gene expression related to the puberty pathway in growing male New Zealand white rabbits., PMID:40172761
Seasonal regulation of Tsh-β, Dio2, Dio3, and GnRH-I mRNA expressions in Eurasian tree sparrow (Passer montanus) under natural conditions., PMID:40108871
Hypotheses in light detection by vertebrate ancient opsin in the bird brain., PMID:40090886
Exploring the therapeutic effect of melatonin targeting common biomarkers in testicular germ cell tumor, prostate adenocarcinoma, and male infertility: an integrated biology approach., PMID:40056207
Prostaglandin E₂ activates the brain-pituitary axis via olfactory pathways in male Bostrychus sinensis., PMID:40020940
Biological and therapeutic implications of sex hormone-related gene clustering in testicular cancer., PMID:40011822
Pituitary gonadotropin-releasing hormone II as a possible mediator of positive estrogen feedback., PMID:39924866
Identification and expression analysis of three gonadotropin-releasing hormone genes in the lined seahorse (Hippocampus erectus)., PMID:39914705
Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches., PMID:39728931
Fishing for the gonadotropin releasing hormone from the genome of Salminus brasiliensis (Characiformes: Bryconidae)., PMID:39476006
Low-temperature-induced disruption of reproductive axis and sperm vitality via stress axis in Monopterus albus., PMID:39368755
A genome-wide CRISPR/Cas9 knockout screen identifies SEMA3F gene for resistance to cyclin-dependent kinase 4 and 6 inhibitors in breast cancer., PMID:39352623
Novel non-peptide uracil-derived human gonadotropin-releasing hormone receptor antagonists., PMID:39342681
The Transcriptome Characterization of the Hypothalamus and the Identification of Key Genes during Sexual Maturation in Goats., PMID:39337542
Homozygous mutation of KISS1 receptor (KISS1R) gene identified in a Chinese patient with congenital hypogonadotropic hypogonadism (CHH): case report and literature review., PMID:39262158
Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R., PMID:39254333
Effects of hypoxia on the reproductive endocrine axis of the pejerrey (Odontesthes bonariensis)., PMID:39235532
Spexin and its receptors in the yellowtail kingfish (Seriola lalandi): identification, expression profiles and reproductive function., PMID:39207579
Elevated temperature impairs gonadal development by suppressing the expression of the genes for kisspeptin, GnRH1 and GTH subunits in Nile tilapia Oreochromis niloticus., PMID:39089445
Non-Hereditary Obesity Type Networks and New Drug Targets: An In Silico Approach., PMID:39062927
Expression of novel androgen receptors in three GnRH neuron subtypes in the cichlid brain., PMID:38986626
Phenytoin causes behavioral abnormalities and suppresses kisspeptin expression, reducing reproductive performance in Japanese medaka., PMID:38943866
Participation of kisspeptin, progesterone, and GnRH receptors on lordosis behavior induced by kisspeptin., PMID:38851441
Genome-wide analysis of two different regions of brain reveals the molecular changes of fertility related genes in rln3a-/- mutants in male Nile tilapia (Oreochromis niloticus)., PMID:38692521
Characterization of Kiss/Kissr system and expression profiling through developmental stages indicate kiss1 to be the active isotype in Clarias magur., PMID:38647980
Lunar Age-Dependent Oscillations in Expression of the Genes for Kisspeptin, GnIH, and Their Receptors in the Grass Puffer during the Spawning Season., PMID:38587522
The expression profiles of cyp19a1, sf-1, esrs and gths in the brain-pituitary during gonadal sex differentiation in juvenile Japanese eels., PMID:38582176
Illuminating the terminal nerve: Uncovering the link between GnRH-1 neuron and olfactory development., PMID:38488687
The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii., PMID:38432348
Development and prenatal exposure to androgens alter potassium currents in gonadotropin-releasing hormone neurons from female mice., PMID:38403894
Effects of dopamine and melatonin treatment on the expression of the genes associated with artificially induced sexual maturation in Japanese eel, Anguilla japonica., PMID:38334250
The effect of gonadotropin-inhibitory hormone on steroidogenesis and spermatogenesis by acting through the hypothalamic-pituitary-testis axis in mice., PMID:38285410
Role of gonadotropin-releasing hormone 2 and its receptor in human reproductive cancers., PMID:38260130
Maternal oral exposure to low-dose BPA accelerates the onset of puberty by promoting prepubertal Kiss1 expression in the AVPV nucleus of female offspring., PMID:38232916
Characterization of reproductive hormones and related gene expression in the hypothalamus and pituitary gland in the egg-laying interval in White King pigeon., PMID:38228063
Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways., PMID:38087324
Central regulation of reproduction in amphibians., PMID:38084833
The functional study of a novel MKRN3 missense mutation associated with familial central precocious puberty., PMID:38054352
Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity., PMID:38052102
Effects of trichlorobisphenol A on the expression of proteins and genes associated with puberty initiation in GT1-7 cells and the relevant molecular mechanism., PMID:38040238
Molecular insights into the effects of tetrachlorobisphenol A on puberty initiation in Wistar rats., PMID:37992829
Postnatal Development and Maintenance of Functional Pituitary Gonadotrophs Is Dependent on PI4-Kinase A., PMID:37935042
Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice., PMID:37898094
Idiopathic hypogonadotropic hypogonadism caused by compound heterozygosity for two novel mutations in the GNRH1 gene: a case report., PMID:37798680
Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats., PMID:37798396
POU6F2 mutation in humans with pubertal failure alters GnRH transcript expression., PMID:37600690
Review: Roles of follicle-stimulating hormone in preantral folliculogenesis of domestic animals: what can we learn from model species and where do we go from here?, PMID:37567683
The late-evolving salmon and trout join the GnRH1 club., PMID:37566258
Investigation of subfertility in the female Nsmf knockout mouse., PMID:37516276
For research use only. Not for human or drug use.
