Catalog No.
FHK26822
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Conjugation
PE
Target
Protein Z39Ig, CRIg, V-set and immunoglobulin domain-containing protein 4, VSIG4, Z39IG
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q9Y279
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0775
VSIG4 Promotes Tumour-Associated Macrophage M2 Polarization and Immune Escape in Colorectal Cancer via Fatty Acid Oxidation Pathway., PMID:40405491
A serum biomarker panel and miniarray detection system for tracking disease activity and flare risk in lupus nephritis., PMID:40375995
VSIG4-Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity., PMID:40346775
Antibodies Targeting Human or Mouse VSIG4 Repolarize Tumor-Associated Macrophages Providing the Potential of Potent and Specific Clinical Anti-Tumor Response Induced across Multiple Cancer Types., PMID:38892347
V-Set and immunoglobulin domain containing (VSIG) proteins as emerging immune checkpoint targets for cancer immunotherapy., PMID:36189222
Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin., PMID:35317169
VISTA Stimulation of VSIG4-Positive Macrophages Strongly Suppresses T Cell Proliferation via Excessive Nitric Oxide Production in Sepsis., PMID:34433706
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways., PMID:32432055
Human Dendritic Cells Express the Complement Receptor Immunoglobulin Which Regulates T Cell Responses., PMID:31921153
CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement., PMID:31723045
NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis., PMID:31288389
VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages., PMID:30662948
V-set and Ig domain-containing 4 (VSIG4)-expressing hepatic F4/80+ cells regulate oral antigen-specific responses in mouse., PMID:29235119
Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity., PMID:27889311
Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy., PMID:27440002
Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis., PMID:27339464
Complement receptor immunoglobulin: a control point in infection and immunity, inflammation and cancer., PMID:27045607
Complement receptor of the immunoglobulin superfamily reduces murine lupus nephritis and cutaneous disease., PMID:25988858
Endogenous VSIG4 negatively regulates the helper T cell-mediated antibody response., PMID:25929804
Monitoring liver macrophages using nanobodies targeting Vsig4: concanavalin A induced acute hepatitis as paradigm., PMID:25440182
A novel CRIg-targeted complement inhibitor protects cells from complement damage., PMID:25114177
Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis., PMID:24686780
Protective role of V-set and immunoglobulin domain-containing 4 expressed on kupffer cells during immune-mediated liver injury by inducing tolerance of liver T- and natural killer T-cells., PMID:22711680
Down-regulation of Z39Ig on macrophages by IFN-gamma in patients with chronic HBV infection., PMID:20399148
A novel inhibitor of the alternative pathway of complement attenuates intestinal ischemia/reperfusion-induced injury., PMID:19691988
Expansion of a unique macrophage subset in rheumatoid arthritis synovial lining layer., PMID:18727628
Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg., PMID:18524992
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis., PMID:17548523
VSIG4, a B7 family-related protein, is a negative regulator of T cell activation., PMID:17016562
To be or not to be B7., PMID:17016555
Z39Ig is expressed on macrophages and may mediate inflammatory reactions in arthritis and atherosclerosis., PMID:16882875
Characterization of monoclonal antibody specific to the Z39Ig protein, a member of immunoglobulin superfamily., PMID:16009265
Z39Ig is co-expressed with activated macrophage genes., PMID:11997108
Cloning of Z39Ig, a novel gene with immunoglobulin-like domains located on human chromosome X., PMID:11004523
For research use only. Not for human or drug use.
