A mass cytometry method pairing T cell receptor and differentiation state analysis., PMID:39191945
Local chicken breeds exhibit abundant TCR-V segments but similar repertoire diversity., PMID:38762097
A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis., PMID:38260336
The redirected killing of PD-L1 positive tumor cells by the expanded mucosa-associated invariant T (MAIT) cells is mediated with a bispecific antibody targeting TCR Vα7.2 and PD-L1., PMID:36621147
Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)., PMID:33157083
In vitro-generated MART-1-specific CD8 T cells display a broader T-cell receptor repertoire than ex vivo naïve and tumor-infiltrating lymphocytes., PMID:30633397
TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features., PMID:30214446
Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity., PMID:29229779
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones., PMID:28945199
CD8αα intraepithelial lymphocytes arise from two main thymic precursors., PMID:28530714
A comprehensive analysis of the germline and expressed TCR repertoire in White Peking duck., PMID:28134319
Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands., PMID:27707880
How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire., PMID:26884163
Examining variable domain orientations in antigen receptors gives insight into TCR-like antibody design., PMID:25233457
A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control., PMID:25082071
Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity., PMID:24813203
Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences., PMID:24415779
A divergent response of innate regulatory T-cells to sepsis in humans: circulating invariant natural killer T-cells are preserved., PMID:24269692
Autoantigen-induced focusing of Vβ13+ T cells precedes onset of autoimmune diabetes in the LEW.1WR1 rat., PMID:24150607
Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes., PMID:23954306
CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire., PMID:23267099
Ex vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in mice., PMID:23136198
Limited T cell receptor repertoire diversity in tuberculosis patients correlates with clinical severity., PMID:23110186
Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor., PMID:22961781
Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3., PMID:22930819
A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay., PMID:22841578
[An anti-human ovarian carcinoma and CD3 bispecific single-chain antibody mediates CDR3 spectratype drift of T cell receptor alpha and beta chains]., PMID:22820567
The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-Cβ antibody., PMID:22575452
Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor., PMID:22412157
Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice., PMID:22315318
TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires., PMID:22053188
Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection., PMID:21690324
A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers., PMID:21683626
Shortening of complementarity determining region 3 of the T cell receptor α chain during thymocyte development., PMID:21126768
Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins., PMID:20735812
Dissection of the IgNAR V domain: molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms., PMID:20450918
Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis., PMID:20439543
Characterization of conserved CDR3 sequence of TCR alpha- and beta-chain genes in peripheral blood T-cells from patients with diffuse large B-cell lymphoma., PMID:20132663
Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions., PMID:19416894
Analysis of T cell receptor Vbeta diversity in peripheral CD4 and CD8 T lymphocytes in patients with autoimmune thyroid diseases., PMID:19040601
An uneven expression of T cell receptor V genes in the arterial wall and peripheral blood in giant cell arteritis., PMID:18975064
Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments., PMID:18962897
Analysis of the interindividual conservation of T cell receptor alpha- and beta-chain variable regions gene in the peripheral blood of patients with systemic lupus erythematosus., PMID:18811695
Localization of NK1.1(+) invariant Valpha19 TCR(+) cells in the liver with potential to promptly respond to TCR stimulation., PMID:18789972
Characterization of a novel nonclassical T cell clone with broad reactivity against human renal cell carcinomas., PMID:18768829
Striking antigen recognition diversity in the Atlantic salmon T-cell receptor alpha/delta locus., PMID:17604101
Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies., PMID:17195241
Most human thymic and peripheral-blood CD4+ CD25+ regulatory T cells express 2 T-cell receptors., PMID:16926292
Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors., PMID:16520393
Role of the T cell receptor alpha chain in the development and phenotype of naturally arising CD4+CD25+ T cells., PMID:16199261