Catalog No.
FHK17212
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
PE
Target
CLAX, C-type lectin domain family 2 member D, Osteoclast inhibitory lectin, CLEC2D, Lectin-like transcript 1, Lectin-like NK cell receptor, OCIL, LLT-1, LLT1
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q9UHP7
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0110
Associations of genetic polymorphisms with clinical response to tocilizumab in Chinese rheumatoid arthritis patients., PMID:39718059
Targeting LLT1 as a potential immunotherapy option for cancer patients non-responsive to existing checkpoint therapies in multiple solid tumors., PMID:39511540
Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies., PMID:38153903
C-TYPE LECTIN-2D RECEPTOR CONTRIBUTES TO HISTONE-INDUCED VASCULAR BARRIER DYSFUNCTION DURING BURN INJURY., PMID:37878490
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis., PMID:33592174
Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer., PMID:32630303
Docetaxel suppresses immunotherapy efficacy of natural killer cells toward castration-resistant prostate cancer cells via altering androgen receptor-lectin-like transcript 1 signals., PMID:32449811
Lectin-like transcript 1 as a natural killer cell-mediated immunotherapeutic target for triple negative breast cancer and prostate cancer., PMID:34322598
Blocking LLT1 (CLEC2D, OCIL)-NKRP1A (CD161) interaction enhances natural killer cell-mediated lysis of triple-negative breast cancer cells., PMID:30034942
Vaccinia virus Western Reserve induces rapid surface expression of a host molecule detected by the antibody 4C7 that is distinct from CLEC2D., PMID:27862195
Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction., PMID:27626681
Genetic and clinical biomarkers of tocilizumab response in patients with rheumatoid arthritis., PMID:27339827
Different genetic associations of the IgE production among fetus, infancy and childhood., PMID:23936416
LLT1-mediated activation of IFN-gamma production in human natural killer cells involves ERK signalling pathway., PMID:20415786
Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells., PMID:18453569
Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein., PMID:16842926
The LLT1 receptor induces IFN-gamma production by human natural killer cells., PMID:15104121
For research use only. Not for human or drug use.
