Catalog No.
YHB90002
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp822-Lys925
Predicted molecular weight
188.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01031
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Epidemiological characteristics of adenovirus in children in Yancheng, China, 2023-2024., PMID:40510801
Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica., PMID:40506785
Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models., PMID:40496615
Precision-Engineered Nano-Electrospray Emitters Enhance Ionization Efficiency for Trap-Assisted Direct Infusion Mass Spectrometry: Application in Plasma Alzheimer's Disease Proteomics., PMID:40490927
[Diagnosis, treatment, and genetic analysis of five cases of primary atypical hemolytic uremic syndrome]., PMID:40484823
Aptamers as therapeutic targets: prospects and progress in the treatment of cancers., PMID:40479828
Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches., PMID:40473811
Characterization and differential expression of DNA methyltransferase and demethylase genes in response to abiotic stress in Isodon rubescens., PMID:40468179
TRIM56 enhances adenoviral E1A steady state to improve oncolytic adenovirus therapy efficacy., PMID:40459263
Complement inhibitor therapy as a steroid-sparing strategy in generalized myasthenia gravis., PMID:40453104
Characterisation of the thermophilic P450 CYP116B305 identified using metagenomics-derived sequence data from an Australian hot spring., PMID:40450052
A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction., PMID:40449486
Recent Findings in N6-Methyladenosine Modification and Significance in Pancreatic Cancer., PMID:40448344
A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS)., PMID:40448185
Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors., PMID:40447351
Isolation and Characterization of E8 Monoclonal Antibodies from Donors Vaccinated with Recombinant Vaccinia Vaccine with Efficient Neutralization of Authentic Monkeypox Virus., PMID:40432083
Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates., PMID:40424786
Construction and Modification of an Efficient Whole-Cell Catalyst for 5-Aminolevulinic Acid Using Induced Protoporphyrin IX as a Marker., PMID:40424032
The Role of Complement in the Pathogenesis and Treatment of Myasthenia Gravis., PMID:40422242
Fibroblast reprogramming in the dura mater of NTG-induced migraine-related chronic hypersensitivity model drives monocyte infiltration via Angptl1-dependent stromal signaling., PMID:40419944
Differential analysis of core complement components expression and localization across rodent, non-human primate, and human ocular tissues., PMID:40419209
Proteomic profiling of serum small extracellular vesicles predicts post-COVID syndrome development., PMID:40419011
Validation for soluble C5b-9 detection and comparative analysis of three quantification methods., PMID:40412754
Long-lasting expression of FosB/ΔFosB immunoreactivity following acute stress in the paraventricular and supraoptic nuclei of the rat hypothalamus., PMID:40412556
Investigating the role of complement 5a in systemic bone loss after myocardial infarction., PMID:40412474
Combination of miRNA148a-3p binding sites and C5-12 promoter in rAAV vector synergistically reduces antigen presentation and transgene immunity., PMID:40404114
Intensified human activities shape the dynamics of sediment organic matter in a highly-disturbed estuary., PMID:40398278
The Protein Kinase Inhibitor, Tyrphostin AG126, and Its Derivatives Suppress Phosphorylation of Plasma Membrane H+-ATPase and Light-Induced Stomatal Opening., PMID:40396646
Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development., PMID:40394223
Discovery of an Orally Bioavailable and Brain Penetrant Selective Estrogen Receptor Degrader., PMID:40393772
Storage and in-use stability of an excipient enhanced growth (EEG) synthetic lung surfactant powder formulation., PMID:40392626
Serum biomarkers of collagen remodeling are associated with intestinal fibrosis and differentiate stenotic from luminal Crohn's disease patients: a pre- and post-resection longitudinal study., PMID:40391838
Hydrophobic Interactions in Aqueous Osmolyte Solutions: Thermodynamics of Solvation and Implication on Protein Stability., PMID:40387874
Inhibition of Alternative and Terminal Complement Pathway Components Modulate the Immune Response Against Bacteria and Fungi in Whole Blood., PMID:40387159
Modulation of TTR gene expression in the eye using modified siRNAs., PMID:40386915
The FvMYB17 targets FvDHQS to promote ellagic acid biosynthesis in strawberry., PMID:40384433
Transcriptome sequencing of Antheraea pernyi antennae for identification of olfactory-related genes., PMID:40383784
Analysis of CD22 cis-ligands using a synthetic sialoside binding to CD22 with ultra-high affinity., PMID:40381245
Complement levels and their diagnostic utility in neonatal sepsis., PMID:40380203
PLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AI™ healthcare database., PMID:40375186
Non-canonical extracellular complement pathways and the complosome paradigm in cancer: a scoping review., PMID:40370471
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis., PMID:40370446
Transient transfection using 222 nm far UV-C irradiation., PMID:40368969
Ravulizumab for generalized Myasthenia Gravis: a multicenter real-life experience., PMID:40366475
Staphylococcus aureus SaeR/S-regulated factors overcome human complement-mediated inhibition of aggregation to evade neutrophil killing., PMID:40359050
[Mahuang Lianqiao Chixiaodou Decoction and its active components inhibit alternative pathway complement activation in rat model of IgA nephropathy]., PMID:40350950
Design, synthesis, anticancer activity evaluation and molecular dynamics study of pyrazine N-oxide-based SHP2 allosteric inhibitors., PMID:40344735
Eculizumab in severe pediatric STEC-HUS and its impact on neurological prognosis-a systematic review and meta-analysis., PMID:40341411
Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis., PMID:40338657
Recent analytical advances in the detection and characterization of 3-O-sulfated heparan sulfate., PMID:40328973
For research use only. Not for human or drug use.
