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Anti-Human CD112/Nectin-2/PVRL2 Antibody (SAA2115), PE

Catalog #:   FHJ32522 Specific References (76) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: FCM
Accession: Q92692
Overview

Catalog No.

FHJ32522

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Conjugation

PE

Target

Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2 receptor-related protein 2, CD112, NECTIN2, HVEB, PRR2, PVRL2

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q92692

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA2115

Data Image
References

Co-blocking TIGIT and PVRIG Using a Novel Bispecific Antibody Enhances Antitumor Immunity., PMID:39851063

Co-blocking TIGIT and PVRIG Using a Novel Bispecific Antibody Enhances Antitumor Immunity., PMID:39851063

CD34+ and CD34- MM cells show different immune-checkpoint molecule expression profiles: high expression of CD112 and CD137 ligand on CD34+ MM cells., PMID:39531203

CD34+ and CD34- MM cells show different immune-checkpoint molecule expression profiles: high expression of CD112 and CD137 ligand on CD34+ MM cells., PMID:39531203

Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial., PMID:39187595

Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial., PMID:39187595

CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells., PMID:38474388

CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells., PMID:38474388

Combined Blockade of TIGIT and PD-L1 Enhances Anti-Neuroblastoma Efficacy of GD2-Directed Immunotherapy with Dinutuximab Beta., PMID:37444427

Combined Blockade of TIGIT and PD-L1 Enhances Anti-Neuroblastoma Efficacy of GD2-Directed Immunotherapy with Dinutuximab Beta., PMID:37444427

Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma., PMID:37383234

Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma., PMID:37383234

Emergence of the CD226 Axis in Cancer Immunotherapy., PMID:35812451

Emergence of the CD226 Axis in Cancer Immunotherapy., PMID:35812451

TgMab-2: An Anti-human T Cell Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain Monoclonal Antibody for Immunocytochemistry., PMID:35736625

TgMab-2: An Anti-human T Cell Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain Monoclonal Antibody for Immunocytochemistry., PMID:35736625

Gene of the month: T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)., PMID:35058314

Gene of the month: T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)., PMID:35058314

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT., PMID:35024316

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT., PMID:35024316

CD155 and CD112 as possible therapeutic targets of FLT3 inhibitors for acute myeloid leukemia., PMID:34992684

CD155 and CD112 as possible therapeutic targets of FLT3 inhibitors for acute myeloid leukemia., PMID:34992684

A descriptive analysis of non-human leukocyte antigens present in renal transplant donor-recipient pairs., PMID:34582968

A descriptive analysis of non-human leukocyte antigens present in renal transplant donor-recipient pairs., PMID:34582968

Innate Immune Checkpoint Inhibitors: The Next Breakthrough in Medical Oncology?, PMID:33850005

Innate Immune Checkpoint Inhibitors: The Next Breakthrough in Medical Oncology?, PMID:33850005

CD112 Regulates Angiogenesis and T Cell Entry into the Spleen., PMID:33467729

CD112 Regulates Angiogenesis and T Cell Entry into the Spleen., PMID:33467729

Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis., PMID:33413573

Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis., PMID:33413573

TIGIT: a novel immunotherapy target moving from bench to bedside., PMID:30232519

TIGIT: a novel immunotherapy target moving from bench to bedside., PMID:30232519

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option., PMID:29855615

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option., PMID:29855615

TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT., PMID:29648914

TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT., PMID:29648914

Development and Characterization of Novel Monoclonal Antibodies Against Human DNAM-1., PMID:28498033

Development and Characterization of Novel Monoclonal Antibodies Against Human DNAM-1., PMID:28498033

Nectin-2 (CD112) Is Expressed on Outgrowth Endothelial Cells and Regulates Cell Proliferation and Angiogenic Function., PMID:27676263

Anti-CD155 and anti-CD112 monoclonal antibodies conjugated to a fluorescent mesoporous silica nanosensor encapsulating rhodamine 6G and fluorescein for sensitive detection of liver cancer cells., PMID:27301350

Anti-CD155 and anti-CD112 monoclonal antibodies conjugated to a fluorescent mesoporous silica nanosensor encapsulating rhodamine 6G and fluorescein for sensitive detection of liver cancer cells., PMID:27301350

CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells., PMID:27296670

CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells., PMID:27296670

Recombinant soluble CD226 protein directly inhibits cancer cell proliferation in vitro., PMID:24468679

Recombinant soluble CD226 protein directly inhibits cancer cell proliferation in vitro., PMID:24468679

CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain., PMID:24451371

CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain., PMID:24451371

Nectin-3 (CD113) interacts with Nectin-2 (CD112) to promote lymphocyte transendothelial migration., PMID:24116228

Nectin-3 (CD113) interacts with Nectin-2 (CD112) to promote lymphocyte transendothelial migration., PMID:24116228

Establishment and characterization of a novel anti-DNAM-1 monoclonal antibody., PMID:23600509

Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226., PMID:22547693

Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226., PMID:22547693

Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma., PMID:22189020

Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma., PMID:22189020

The cell surface proteome of human mesenchymal stromal cells., PMID:21637820

The cell surface proteome of human mesenchymal stromal cells., PMID:21637820

Identification of endothelial cell junctional proteins and lymphocyte receptors involved in transendothelial migration of human effector memory CD4+ T cells., PMID:21191062

Identification of endothelial cell junctional proteins and lymphocyte receptors involved in transendothelial migration of human effector memory CD4+ T cells., PMID:21191062

A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions., PMID:20081873

A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions., PMID:20081873

[Preparation and characterization of monoclonal antibodies against human CD112 (Nectin2/PRR2)]., PMID:17428395

[Preparation and characterization of monoclonal antibodies against human CD112 (Nectin2/PRR2)]., PMID:17428395

The switch from latent to productive infection in epstein-barr virus-infected B cells is associated with sensitization to NK cell killing., PMID:17079298

The switch from latent to productive infection in epstein-barr virus-infected B cells is associated with sensitization to NK cell killing., PMID:17079298

Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process., PMID:16831868

Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process., PMID:16831868

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis., PMID:15607800

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis., PMID:15607800

DNAM-1 and PVR regulate monocyte migration through endothelial junctions., PMID:15136589

DNAM-1 and PVR regulate monocyte migration through endothelial junctions., PMID:15136589

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)., PMID:15039383

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)., PMID:15039383

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule., PMID:12913096

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule., PMID:12913096

Retinoid regulation of human cathepsin D gene expression., PMID:8639464

Retinoid regulation of human cathepsin D gene expression., PMID:8639464

Datasheet
$ 258
Product specifications
50 T 258 100 T 426

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Anti-Human CD112/Nectin-2/PVRL2 Antibody (SAA2115), PE [FHJ32522]
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