Catalog No.
YHB89501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu25-Lys418
Predicted molecular weight
46.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01009
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AAT, SPAAT, PI, Alpha-1 protease inhibitor, Alpha-1-antitrypsin, Alpha-1-antiproteinase, SERPINA1, Serpin A1
a1-antitrypsin, a new biomarker of polycystic ovary syndrome by changing its expression and rhythm., PMID:40420300
Chaperone-mediated autophagy degrades SERPINA1E342K/α1-antitrypsin Z variant and alleviates cell stress., PMID:40114294
Differentiated approach to management of patients with irritable bowel syndrome and ulcerative colitis in non-alcoholic fatty liver disease., PMID:39661894
Specifics of barrier function impairment of the large intestine in patients with ulcerative collitis and joint damage., PMID:39661892
Bladder cancer risk stratification with the Oncuria 10-plex bead-based urinalysis assay using three different Luminex xMAP instrumentation platforms., PMID:38167321
Bladder cancer risk stratification with the Oncuria 10-plex bead-based urinalysis assay using three different Luminex xMAP instrumentation platforms., PMID:38045238
Small airways disease in patients with alpha-1 antitrypsin deficiency., PMID:36965591
Severe COVID-19 Illness and α1-Antitrypsin Deficiency: COVID-AATD Study., PMID:36831051
Optimizing the screening of alpha-1 antitrypsin deficiency using serum protein electrophoresis., PMID:36420543
Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice., PMID:34422975
Placental HTRA1 cleaves α1-antitrypsin to generate a NET-inhibitory peptide., PMID:34192300
Impact of serine protease inhibitor alpha1-antitrypsin on expression of endoplasmic reticulum stress-induced proinflammatory factors in adipocytes., PMID:33732904
Plasma Cytokeratin 18 and fecal Alpha-1 Antitrypsin concentrations in dogs with osteosarcoma receiving carboplatin chemotherapy., PMID:33222415
A Quantitative Global Proteomics Approach Identifies Candidate Urinary Biomarkers That Correlate With Intraductal Papillary Mucinous Neoplasm Dysplasia., PMID:32769857
Two-Dimensional Differential Gel Electrophoresis to Identify Protein Biomarkers in Amniotic Fluid of Edwards Syndrome (Trisomy 18) Pregnancies., PMID:26752631
Proteomic analysis of plasma from rats following total parenteral nutrition-induced liver injury., PMID:26314240
Alpha-1-antitrypsin: a novel human high temperature requirement protease A1 (HTRA1) substrate in human placental tissue., PMID:25329061
Peptidic HIV-1 fusion inhibitor VIR576 as a potential dual- functional microbicide inhibits antigen-specific CD4(+) T-cell activation., PMID:24849419
A rare variant of α 1 antitrypsin mutations detected in Vietnamese children with liver disease., PMID:23766346
Alpha 1-antitrypsin activity is markedly decreased in Wegener's granulomatosis., PMID:23604680
Metabolism and metabolic burden by α1-antitrypsin production in human AGE1.HN cells., PMID:23376655
Genetic modifiers of liver injury in hereditary liver disease., PMID:21538285
Levels of alpha1-antitrypsin in plasma and risk of spontaneous cervical artery dissections: a case-control study., PMID:12893950
Course of serum lipoprotein(a) and acute phase protein levels in patients undergoing open heart surgery., PMID:12483171
Variation at 10 protein coding loci in the Mbenzele Pygmies from the Central African Republic and a comparison with microsatellite data., PMID:11911457
The concentration of alpha 1-antitrypsin in the maternal serum after delivery of normal and small for gestational age infants., PMID:11199152
A study of the effects of extracorporeal circulation on the immunologic system of humans., PMID:8969397
Alpha-1-antitrypsin, CRP and interleukin-6 in ANCA-positive vasculitis., PMID:8296630
Some humoral immunological aspects of the rheumatoid arthritis correlated with the ultrastructural changes of the rheumatoid synovial fluid., PMID:1285262
Metabolic activity in inflammatory and non-inflammatory aneurysms of the abdominal aorta., PMID:1374041
[Alpha 1-antitrypsin as an endogenous marker of protein-losing enteropathies]., PMID:1437795
Disruption of the LF-A1 and LF-B1 binding sites in the human alpha-1-antitrypsin gene has a differential effect during development in transgenic mice., PMID:1717262
Cell marker studies in undifferentiated soft tissue sarcoma., PMID:1752649
Elastase inhibitory activity in serum of patients with thyroid dysfunction., PMID:1899059
[Alpha 1-antitrypsin and its phenotype in patients with asthma and aspirin hypersensitivity]., PMID:1843906
Leukocyte and serum elastase in response to elective surgical trauma., PMID:2808504
The associations between serum alpha-1-antitrypsin level and the whole blood contents of trace metals in normal women in reproductive age., PMID:2488460
Cerebrospinal fluid alpha-1-antitrypsin alpha-1-antitrypsin-elastase complex levels in meningitis., PMID:2499458
Immunocytochemistry of anaplastic carcinoma of thyroid gland., PMID:2471539
An immunohistochemical study of normal human neonate and adult parotid gland tissue. Detection of lysozyme, lactoferrin, a1-antichymotrypsin, a1-antitrypsin and carcinoembryonic antigen., PMID:3047715
Radiographic assessment in relation to clinical and biochemical variables in rheumatoid arthritis., PMID:3266030
A zone electrophoretic-isoelectric focusing study on the inactivation of human alpha 1-antitrypsin by elastase., PMID:3154962
[Fecal alpha 1-antitrypsin clearance in protein-losing enteropathies in pediatrics]., PMID:3502057
Complete absence of serum alpha-1-antitrypsin in conjunction with an apparently normal gene structure., PMID:3014871
Protein conservation by the immature intestine., PMID:3871337
Genetic heterogeneity of rabbit alpha-1-antitrypsin., PMID:6609100
An immunocytochemical study of the distribution of lysozyme, a1-antitrypsin and a1-antichymotrypsin in the normal and pathological gall bladder., PMID:6428042
Comparative immunostaining of T-associated plasma cells and other lymph-node cells in paraffin sections., PMID:6136117
Immunocytochemical demonstration of a1-Antitrypsin and a1-Antichymotrypsin in human gastrointestinal tract., PMID:6983995
[Alpha 1-antitrypsin (A-1-AT) level in bronchial asthma]., PMID:6969951