Catalog No.
YHB88501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr573-Leu761
Predicted molecular weight
23.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00751
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Properdin factor B, Complement factor B, GBG, Glycine-rich beta glycoprotein, BFD, C3/C5 convertase, CFB, PBF2, BF
Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038
Astrogliosis Occurs Selectively in Amygdala of Adolescent Primate and Rodent Following Daily Δ9-Tetrahydrocannabinol, Prevented by Cannabidiol Co-Treatment., PMID:40487783
Efficacy of zilucoplan in patients with generalised myasthenia gravis who have not previously received immunoglobulin or plasma exchange: A subgroup analysis from the Phase 3 RAISE study., PMID:40450840
Patient-reported outcomes with trastuzumab deruxtecan in hormone receptor-positive, HER2-low or HER2-ultralow metastatic breast cancer: results from the randomized DESTINY-Breast06 trial., PMID:40441802
Complement and Coagulation Cascade Activation Regulates the Early Inflammatory Mechanism of Resistance of Suckling Lambs Against Haemonchus contortus., PMID:40430767
Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series., PMID:40414239
TLR7 responses in glomerular macrophages accelerate the progression of glomerulonephritis in NZBWF1 mice., PMID:40401698
Epigenetic modifications in cardiac fibrosis: recent evidence of new pharmacological targets., PMID:40384946
PCR targeting 16S rRNA, cfb, and hylB for group B Streptococcus detection in women with 35 to 37 weeks of pregnancy., PMID:40351010
[Mahuang Lianqiao Chixiaodou Decoction and its active components inhibit alternative pathway complement activation in rat model of IgA nephropathy]., PMID:40350950
Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689
SAA1 Protein: A Potential Biomarker for Acute Myeloid Leukemia., PMID:40299483
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol., PMID:40254411
Early α-synuclein aggregation decreases corticostriatal glutamate drive and synapse density., PMID:40250719
Patisiran Treatment in the Brazilian Subpopulation of the Phase 3 APOLLO-B Study in Transthyretin Amyloidosis with Cardiomyopathy: Post Hoc Analysis., PMID:40243852
Efficacy and Safety of Zimlovisertib, Ritlecitinib, and Tofacitinib, Alone and in Combination, in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate., PMID:40223599
Genotypes of SNPs of key genes regulate susceptibility and drug sensitivity to neovascular AMD in the human population., PMID:40221144
Navacaprant, a Novel and Highly Selective Kappa Opioid Receptor Antagonist, in Adults With Major Depressive Disorder: A Randomized, Double-Blind Phase 2 Clinical Trial., PMID:40199329
A bovine pulmosphere model and multiomics reveal early host response signature in tuberculosis., PMID:40186000
Reference intervals for serum immunoglobulin A, G, and M in a Danish paediatric population-based cohort., PMID:40174761
Large-scale Plasma Proteomic Profiling Unveils Novel Diagnostic Biomarkers and Pathways for Alzheimer's Disease., PMID:40166037
M28 family peptidase derived from Peribacillus frigoritolerans initiates trained immunity to prevent MRSA via the complosome-phosphatidylcholine axis., PMID:40159598
CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system., PMID:40102632
Relating the molecular phenotype of ulcerative colitis to the clinical course., PMID:40064933
Genome-wide mapping of complement system proteins for islet autoimmunity in the DAISY and TEDDY children., PMID:39989961
An intracellular complement system drives metabolic and proinflammatory reprogramming of vascular fibroblasts in pulmonary hypertension., PMID:39946184
Complement Factor B Deficiency Is Dispensable for Female Fertility but Affects Microbiome Diversity and Complement Activity., PMID:39941161
Plasma proteome fingerprint in kidney diseases., PMID:39896931
The role of the complement system in Shiga toxin-associated hemolytic uremic syndrome., PMID:39792253
Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies., PMID:39753879
Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy., PMID:39752339
α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen-Glucose Deprivation/Reoxygenation., PMID:39718716
A non-invasive model for diagnosis of primary Sjogren's disease based on salivary biomarkers, serum autoantibodies, and Schirmer's test., PMID:39695856
Effectiveness of cognitive fusion transrectal ultrasound prostate biopsy when compared with final prostatectomy histology., PMID:39692407
The molecular mechanism of Xiaoyaosan in treating major depressive disorder: Integrated analysis of DNA methylation and RNA sequencing of the arcuate nucleus in rats., PMID:39675591
E-52862-A selective sigma-1 receptor antagonist, in peripheral neuropathic pain: Two randomized, double-blind, phase 2 studies in patients with chronic postsurgical pain and painful diabetic neuropathy., PMID:39629978
Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion., PMID:39587546
Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration., PMID:39585675
Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding., PMID:39574582
Calcium Fructoborate Improves Knee Osteoarthritis in Rats by Activating Hedgehog Signaling Through DDIT3., PMID:39572483
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Long-read sequencing for detection and subtyping of Prader-Willi and Angelman syndromes., PMID:39537351
Prognostic value of patient-reported outcomes in advanced or metastatic melanoma patients treated with immunotherapy: Findings from the CheckMate-067 study., PMID:39520835
Expanded Field OCT Angiography Biomarkers for Predicting Clinically Significant Outcomes in Non-Proliferative Diabetic Retinopathy., PMID:39490720
Identification of Plasma Protein Biomarkers for Predicting Lung Cancer., PMID:39477293
Efficacy, safety and tolerability of GSK3858279, an anti-CCL17 monoclonal antibody and analgesic, in healthy volunteers and patients with knee osteoarthritis pain: a phase I, randomised, double-blind, placebo-controlled, proof-of-mechanism and proof-of-concept study., PMID:39419538
Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling., PMID:39410666
Effect of Feed on the Growth Performance, Nutrition Content and Cost of Raising the Field Cricket (Gryllus madagascarensis) as a Sustainable Nutrient Source in Madagascar., PMID:39410175
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
For research use only. Not for human or drug use.
