Catalog No.
YHB88401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser36-Thr126
Predicted molecular weight
12.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00750
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
t-plasminogen activator, tPA, t-PA, Reteplase, Tissue-type plasminogen activator, Alteplase, PLAT,Tenecteplase
Single-cell multi-omics reveals that FABP1 + renal cell carcinoma drive tumor angiogenesis through the PLG-PLAT axis under fatty acid reprogramming., PMID:40518526
Mutation in soybean Lox-2 PLAT/LH2 domain through CRISPR/Cas9 reduces seed lipoxygenase activity: responsible for undesirable flavour., PMID:40498336
Combined effects and potential mechanisms of volatile organic compounds on thyroid disease in the US population: An integrated epidemiological and computational toxicology study., PMID:40378728
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Transcriptomic analysis reveals distinct molecular signatures and regulatory networks of osteoarthritic chondrocytes versus mesenchymal stem cells during chondrogenesis., PMID:40242907
Identification of the potential role of S1PR1 in adult moyamoya disease based on multiple bioinformatics analysis and experimental verification., PMID:40105149
Integrative multi-omics analysis reveals molecular signatures of central obesity in children., PMID:40044886
Effect of blood purification combined with antibiotics on CC-16 and SP-D levels and prognosis in patients with severe acute pancreatitis complicated by acute respiratory distress syndrome., PMID:39959207
Effects of four-weeks porcine-collagen hydrolysate consumption on glucose concentrations, glycemic variability, and fasting/postprandial cardiometabolic risk markers in men and women with overweight or obesity: A randomized, controlled trial., PMID:39889494
Fetal Fibroblast Heterogeneity Defines Dermal Architecture during Human Embryonic Skin Development., PMID:39880186
Vvax001, a Therapeutic Vaccine, for Patients with HPV16-Positive High-grade Cervical Intraepithelial Neoplasia: A Phase II Trial., PMID:39849926
Effects of Longer-Term Mixed Nut Consumption on Lipoprotein Particle Concentrations in Older Adults with Overweight or Obesity., PMID:39796442
Molecular subtype of gastric cancer based on apoptosis-related genes reveals differential immune microenvironment and intratumoral microorganisms distribution., PMID:39762768
The performance of a lateral flow SARS-CoV-2 antibody assay and semi-autonomous SARS-CoV-2 antisense and sense RNA fluorescence in situ hybridization assay in a prospective cohort pilot study within a Dutch military population., PMID:39739954
Identification of the arachidonic acid 5-lipoxygenase and its function in the immunity of Apostichopus japonicus., PMID:39732381
Long-term egg-protein hydrolysate consumption improves endothelial function: a randomized, double-blind, placebo-controlled trial in older adults with overweight or obesity., PMID:39718599
TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury., PMID:39680199
Identification of key signaling pathways and novel computational drug target for oral cancer, metabolic disorders and periodontal disease., PMID:39674633
Identification of Novel Proteins Mediating Causal Association Between Smoking and Essential Hypertension: A Mendelian Randomization Study., PMID:39604029
Effects of long-term almond consumption on markers for vascular function and cardiometabolic risk in men and women with prediabetes: results of a randomized, controlled cross-over trial., PMID:39546040
Recommended or high daily intakes of plant stanol esters do not affect ex vivo T-cell derived cytokine production in immunologically healthy volunteers., PMID:39506323
RNA sequencing reveals transcriptomic changes in PC-12 cells following plasminogen activator, tissue type overexpression., PMID:39430838
Vitis vinifera Lipoxygenase LoxA is an Allosteric Dimer Activated by Lipidic Surfaces., PMID:39424098
The Role of Lymph-Adipose Crosstalk in Alcohol-Induced Perilymphatic Adipose Tissue Dysfunction., PMID:39409139
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study., PMID:39377880
Addressing residual risk beyond statin therapy: New targets in the management of dyslipidaemias-A report from the European Society of Cardiology Cardiovascular Round Table., PMID:39289123
The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity., PMID:39245780
FDA Approval Summary: Enfortumab Vedotin plus Pembrolizumab for Locally Advanced or Metastatic Urothelial Carcinoma., PMID:39230571
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study., PMID:39227583
Fibrinolysis is impaired in patients with primary immune thrombocytopenia., PMID:39214313
Pan-cancer analysis identifies venous thromboembolism-related genes F3, PLAT, and C1S as potential prognostic biomarkers for glioblastoma and lower grade glioma., PMID:39179711
B cells critical for outcome in high grade serous ovarian carcinoma., PMID:39175107
Identification of HTRA1, DPT and MXRA5 as potential biomarkers associated with osteoarthritis progression and immune infiltration., PMID:39148085
"Cruising together"-ASC specks and SAA, a perfect match in chronic inflammation., PMID:39080494
MAP3K8 is a potential therapeutic target in airway epithelial inflammation., PMID:39030600
Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes., PMID:38977927
CHI3L1 on fibrinolytic system imbalance in chronic rhinosinusitis with nasal polyp., PMID:38975344
Immune predictors of response to immune checkpoint inhibitors in mismatch repair-deficient endometrial cancer., PMID:38955419
Unique regulatory network of dragon fruit simultaneously mitigates the effect of vanadium pollutant and environmental factors., PMID:38952344
Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059., PMID:38907948
Real-world outcomes of pemetrexed-platinum chemotherapy plus osimertinib after progression on first-line osimertinib in advanced EGFR-mutated NSCLC., PMID:38889498
Long-term effects of an egg-protein hydrolysate on cognitive performance and brain vascular function: a double-blind randomized controlled trial in adults with elevated subjective cognitive failures., PMID:38703228
Short-term Aronia melanocarpa extract supplementation improves cognitive performance: a randomized, double-blind, placebo-controlled cross-over study in healthy young adults., PMID:38656355
Identification of chemoresistance associated key genes-miRNAs-TFs in docetaxel resistant breast cancer by bioinformatics analysis., PMID:38590544
A de novo PKD1 mutation in a Chinese family with autosomal dominant polycystic kidney disease., PMID:38552045
Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing., PMID:38502193
In platelet single donor apheresis, platelet factor 4 levels correlated with donor's age and decreased during storage., PMID:38485973
Serpin peptidase inhibitor, clade E, member 2 in physiology and pathology: recent advancements., PMID:38469181
Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat., PMID:38407813
Lung single-cell RNA profiling reveals response of pulmonary capillary to sepsis-induced acute lung injury., PMID:38348045
For research use only. Not for human or drug use.
