Structural Features of Glypicans and their Impact on Wnt Signaling in Cancer., PMID:40416340
Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancer., PMID:39793167
The anti-glypican 1 AT101 antibody as targeting agent to effectively deliver chitosan nanobubbles to glioblastoma cells., PMID:39620421
IRTIDP: A simple integrated real-time isolation and detection platform for small extracellular vesicles Glypican-1 in pancreatic cancer patients., PMID:39191106
Interplay between glypican-1, amyloid-β and tau phosphorylation in human neural stem cells., PMID:38992568
Evaluation of antitumor potential of an anti-glypican-1 monoclonal antibody in preclinical lung cancer models reveals a distinct mechanism of action., PMID:38966167
Codetection of Proteins and RNAs on Extracellular Vesicles for Pancreatic Cancer Early Diagnosis., PMID:38626343
Glypican-1-targeted antibody-drug conjugate inhibits the growth of glypican-1-positive glioblastoma., PMID:38417223
A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma., PMID:38017492
Integrated FET sensing microsystem for specific detection of pancreatic cancer exosomal miRNA10b., PMID:37996166
Immuno-PET and Targeted α-Therapy Using Anti-Glypican-1 Antibody Labeled with 89Zr or 211At: A Theranostic Approach for Pancreatic Ductal Adenocarcinoma., PMID:37827841
Promising Highly Targeted Therapies for Cholangiocarcinoma: A Review and Future Perspectives., PMID:37509347
Quantification of GPC1(+) Exosomes Based on MALDI-TOF MS In Situ Signal Amplification for Pancreatic Cancer Discrimination and Evaluation., PMID:37368911
Dual Tumor Exosome Biomarker Co-recognitions Based Nanoliquid Biopsy for the Accurate Early Diagnosis of Pancreatic Cancer., PMID:37288703
Nano-particulate Toll-like Receptor 9 Agonist Potentiates the Antitumor Activity of Anti-Glypican-1 Antibody., PMID:37247902
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer., PMID:37031249
Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior., PMID:36944188
Interplay between APP and glypican-1 processing and α-synuclein aggregation in undifferentiated and differentiated human neural progenitor cells., PMID:36790131
Pharmacokinetics and Biodistribution of 89Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma., PMID:36602058
The Proteoglycan Glypican-1 as a Possible Candidate for Innovative Targeted Therapeutic Strategies for Pancreatic Ductal Adenocarcinoma., PMID:36142190
GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling., PMID:35312769
Clinical development of an anti-GPC-1 antibody for the treatment of cancer., PMID:35067148
Complex modulation of cytokine-induced α-synuclein aggregation by glypican-1-derived heparan sulfate in neural cells., PMID:34939110
Radioimmunotherapy for solid tumors: spotlight on Glypican-1 as a radioimmunotherapy target., PMID:34646364
Glypican-1 Is a Novel Target for Stroma and Tumor Cell Dual-Targeting Antibody-Drug Conjugates in Pancreatic Cancer., PMID:34583978
Role of glypican-1 in regulating multiple cellular signaling pathways., PMID:34550795
Combining Fluorescent Cell Sorting and Single B Cell Amplification to Screen the Monoclonal Antibody Gene against Human Glypican-1 in Pancreatic Cancer., PMID:34527051
A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma., PMID:34332450
Safety and tolerability of Miltuximab® - a first in human study in patients with advanced solid cancers., PMID:34250138
Anti-Glypican-1 Antibody-drug Conjugate as Potential Therapy Against Tumor Cells and Tumor Vasculature for Glypican-1-Positive Cholangiocarcinoma., PMID:34224365
Reversal of apolipoprotein E4-dependent or chemical-induced accumulation of APP degradation products by vitamin C-induced release of heparan sulfate from glypican-1., PMID:33403386
A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells., PMID:33302918
Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform., PMID:33224932
The feasibility of Miltuximab®-IRDye700DX-mediated photoimmunotherapy of solid tumors., PMID:33069874
Sensitive Signal Amplifying a Diagnostic Biochip Based on a Biomimetic Periodic Nanostructure for Detecting Cancer Exosomes., PMID:32603586
Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)., PMID:32382920
Near-Infrared Molecular Imaging of Glioblastoma by Miltuximab®-IRDye800CW as a Potential Tool for Fluorescence-Guided Surgery., PMID:32316186
GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab., PMID:32228854
Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer., PMID:32152502
Proinflammatory cytokines induce accumulation of glypican-1-derived heparan sulfate and the C-terminal fragment of β-cleaved APP in autophagosomes of dividing neuronal cells., PMID:32039447
Rapid and Label-Free Isolation of Tumour Cells from the Urine of Patients with Localised Prostate Cancer Using Inertial Microfluidics., PMID:31905736
Functionalized Upconversion Nanoparticles for Targeted Labelling of Bladder Cancer Cells., PMID:31816991
Multivalency Interface and g-C3N4 Coated Liquid Metal Nanoprobe Signal Amplification for Sensitive Electrogenerated Chemiluminescence Detection of Exosomes and Their Surface Proteins., PMID:31469261
Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer., PMID:30425490
Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody., PMID:30202003
Glypican-1-antibody-conjugated Gd-Au nanoclusters for FI/MRI dual-modal targeted detection of pancreatic cancer., PMID:29750031
Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer., PMID:29672570
Glypican-1 immunohistochemistry is a novel marker to differentiate epithelioid mesothelioma from lung adenocarcinoma., PMID:29327712
Anti-glypican-1 antibody-drug conjugate exhibits potent preclinical antitumor activity against glypican-1 positive uterine cervical cancer., PMID:29055044
Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma., PMID:28445969