Catalog No.
FHD97912
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
PE
Target
IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, RHD97901
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P31994
Applications
ELISA, FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0547
Human Fcγ-receptors selectively respond to C-reactive protein isoforms., PMID:40458392
FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs., PMID:40089806
Fc gamma receptors activate different protein kinase C isoforms in human neutrophils., PMID:39946245
The A-HIPI prediction model in advanced-stage Hodgkin lymphoma: identification of risk groups and creation of an online tool., PMID:39778124
A Competition-Based Strategy for the Isolation of an Anti-Idiotypic Blocking Module and Fine-Tuning for Conditional Activation of a Therapeutic Antibody., PMID:39655405
FGL2/FcγRIIB Signalling Mediates Arterial Shear Stress-Mediated Endothelial Cell Apoptosis: Implications for Coronary Artery Bypass Vein Graft Pathogenesis., PMID:39062880
ACE2 decoy Fc-fusions and bi-specific killer engager (BiKEs) require Fc engagement for in vivo efficacy against SARS-CoV-2., PMID:38948747
A Novel Anti-CD38 Monoclonal Antibody for Treating Immune Thrombocytopenia., PMID:38899695
Plant-derived Durvalumab variants show efficient PD-1/PD-L1 blockade and therapeutically favourable FcR binding., PMID:38050338
Long-Term Follow-Up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma Trial., PMID:37883739
Immunomodulatory effects of intravenous and subcutaneous immunoglobulin in chronic inflammatory demyelinating polyneuropathy: An observational study., PMID:37789648
FcγRIIB expressed on CD8+ T cells limits responsiveness to PD-1 checkpoint inhibition in cancer., PMID:37611081
FcγR requirements and costimulatory capacity of Urelumab, Utomilumab, and Varlilumab., PMID:37575254
Differential Efficacy From the Addition of Bortezomib to R-CHOP in Diffuse Large B-Cell Lymphoma According to the Molecular Subgroup in the REMoDL-B Study With a 5-Year Follow-Up., PMID:36972491
CIDP: Analysis of Immunomarkers During COVID-19 mRNA-Vaccination and IVIg-Immunomodulation: An Exploratory Study., PMID:36929282
The CD16 and CD32b Fc-gamma receptors regulate antibody-mediated responses in mouse natural killer cells., PMID:36822164
Bispecific killer cell engager with high affinity and specificity toward CD16a on NK cells for cancer immunotherapy., PMID:36685519
A Review of Margetuximab-Based Therapies in Patients with HER2-Positive Metastatic Breast Cancer., PMID:36612034
Down-regulated FcγRII expression on plasma cells is associated with the disease activity of ANCA-associated vasculitis., PMID:36111855
FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms., PMID:35858562
The Antibody Dependant Neurite Outgrowth Modulation Response Involvement in Spinal Cord Injury., PMID:35784350
Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma., PMID:35610242
Role of Fcγ receptors in HER2-targeted breast cancer therapy., PMID:34992090
Erratum to: An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability., PMID:34905057
Evaluation of the FCGR2B polymorphism in children with immune thrombocytopenia., PMID:34859644
An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability., PMID:34687301
Prognostic significance of FCGR2B expression for the response of DLBCL patients to rituximab or obinutuzumab treatment., PMID:34323958
Subclasses of allergen-specific IgG: Serum IgG2 and IgG3 levels are not predicted by IgG1/IgG4 levels., PMID:34192382
Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension., PMID:33980031
Margetuximab: First Approval., PMID:33761116
Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via FcγRIIb on Liver Sinusoidal Endothelial Cells by Endocytosis., PMID:33568400
FcγRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis., PMID:33505402
Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes., PMID:33424774
IgE and mast cells: The endogenous adjuvant., PMID:33190734
Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys., PMID:33188207
Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus., PMID:32945349
Efficacy and safety results from CheckMate 140, a phase 2 study of nivolumab for relapsed/refractory follicular lymphoma., PMID:32870269
Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies., PMID:32847974
FcγR2B B2.4 haplotype predicts increased risk of red blood cell alloimmunization in sickle cell disease patients., PMID:32681817
Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context., PMID:32678124
Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis., PMID:32613944
Glycosylation of Fcγ receptors influences their interaction with various IgG1 glycoforms., PMID:32222585
Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity., PMID:31940267
Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens., PMID:31866435
Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection., PMID:31824485
CD4+CD19+ conjugates favor HIV-1 infection and latency during chronic HIV-1 infection., PMID:31634199
Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial., PMID:31434737
FcγRIIB-I232T polymorphic change allosterically suppresses ligand binding., PMID:31343409
Decreased expression of FcγRII in active Graves' disease patients., PMID:31033004
Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody., PMID:30950681
For research use only. Not for human or drug use.
