Catalog No.
YHB86601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr3-Ala218
Predicted molecular weight
51.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00492
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HPRT, HPRT1, HGPRT, HGPRTase, Hypoxanthine-guanine phosphoribosyltransferase
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study., PMID:40508129
Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning., PMID:40360670
Identification of potential inhibitors of hypoxanthine-guanine phosphoribosyl transferase for cancer treatment by molecular docking, dynamics simulation and in vitro studies., PMID:40126362
[Exploration of pharmacodynamic substances and potential mechanisms of Huazhuo Sanjie Chubi Decoction in treatment of gouty arthritis based on UPLC-Q-Exactive Orbitrap-MS technology and network pharmacology]., PMID:39929626
Effect of PI3-kinase inhibitors on DNA double strand break repair pathways: observations using a site specific DSB induction system., PMID:39540507
HPRT1: a preliminary investigation on its involvement in nasopharyngeal carcinoma., PMID:39505752
Metformin improves HPRT1-targeted purine metabolism and repairs NR4A1-mediated autophagic flux by modulating FoxO1 nucleocytoplasmic shuttling to treat postmenopausal osteoporosis., PMID:39500875
Screening and validating the optimal panel of housekeeping genes for 4T1 breast carcinoma and metastasis studies in mice., PMID:39488625
HIF-1α-HPRT1 axis promotes tumorigenesis and gefitinib resistance by enhancing purine metabolism in EGFR-mutant lung adenocarcinoma., PMID:39343971
Reference gene evaluation for normalization of gene expression studies with lymph tissue and node‑derived stromal cells of patients with oral squamous cell carcinoma., PMID:39310029
Comprehensive identification of ubiquitin-like 3 (UBL3)-interacting proteins in the mouse brain., PMID:39148092
BCORL1, POF1B, and USP9X copy number variation in women with idiopathic diminished ovarian reserve., PMID:38995507
Revisiting the impact of genomic hot spots: C12orf35 locus as a hot spot and engineering target., PMID:38978356
Identifying the immunoglobulin G transporter in equine tissues: A look at the neonatal Fc receptor., PMID:38879095
SCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer's disease., PMID:38871989
Hypoxia related genes modulate in similar fashion in skin fibroblast cells of yak (Bos grunniens) adapted to high altitude and native cows (Bos indicus) adapted to tropical climate during hypoxia stress., PMID:38814473
Quantitative proteomics revealed protein biomarkers to distinguish malignant pleural effusion from benign pleural effusion., PMID:38768894
Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway., PMID:38750091
Alleviation of doxorubicin adverse effects via loading into various drug-delivery systems: a comparative study., PMID:38639647
Network pharmacology and experimental evaluation strategies to decipher the underlying pharmacological mechanism of Traditional Chinese Medicine CFF-1 against prostate cancer., PMID:38484140
PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure., PMID:38471523
Synthetic reversed sequences reveal default genomic states., PMID:38448583
Validation of Endogenous Control Genes by Real-Time Quantitative Reverse Transcriptase Polymerase Chain Reaction for Acute Leukemia Gene Expression Studies., PMID:38397141
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements., PMID:38233393
Selection of reference genes in liproxstatin-1-treated K562 Leukemia cells via RT-qPCR and RNA sequencing., PMID:38165476
Generation of an iPSC line (SDQLCHi030-A) derived from PBMCs of a patient with Lesch-Nyhan syndrome caused by HPRT1 mutation., PMID:38154384
Screening and Identifying Reference Genes for Erythrocyte Production from Cord Blood CD34+ Cells Exposed to Hypoxia., PMID:38011643
Systemic infusion of TLR3-ligand and IFN-α in patients with breast cancer reprograms local tumor microenvironments for selective CTL influx., PMID:37963636
Insensitive Effects of Inflammatory Cytokines on the Reference Genes of Synovial Fluid Resident-Mesenchymal Stem Cells Derived from Rheumatoid Arthritis Patients., PMID:37894839
DNA Damage Induced by T-2 Mycotoxin in Human Skin Fibroblast Cell Line-Hs68., PMID:37833905
Red Blood Cells from Individuals with Lesch-Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency., PMID:37760001
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas., PMID:37737247
YWHAZ and TBP are potential reference gene candidates for qPCR analysis of response to radiation therapy in colorectal cancer., PMID:37558778
Discovering functionally important sites in proteins., PMID:37443362
[Circular RNA hsa_circ_0087893 participates in intraventricular hemorrhage occurrence and progression possibly as a competitive endogenous RNA in preterm infants]., PMID:37313816
Differential Proteomic Analysis of Human Sperm: A Systematic Review to Identify Candidate Targets to Monitor Sperm Quality., PMID:37118964
Identification of stable reference genes for quantitative gene expression analysis in the duodenum of meat-type ducks., PMID:37077952
PI3K/ c-Myc/AFF4 axis promotes pancreatic tumorigenesis through fueling nucleotide metabolism., PMID:37063434
Identification of Optimal Reference Genes for qRT-PCR Normalization for Physical Activity Intervention and Omega-3 Fatty Acids Supplementation in Humans., PMID:37047706
Human Papillomavirus E7 and p16INK4a mRNA Multiplexed Quantification by a QuantiGeneTM Proof-of-Concept Assay Sensitively Detects Infection and Cervical Dysplasia Severity., PMID:36980443
Systematic Identification of the Optimal Housekeeping Genes for Accurate Transcriptomic and Proteomic Profiling of Tissues following Complex Traumatic Injury., PMID:36961042
Identification of Hub Genes Associated with Resistance to Prednisolone in Acute Lymphoblastic Leukemia Based on Weighted Gene Co-expression Network Analysis., PMID:36877306
Mechanism of anti-hyperuricemia of isobavachin based on network pharmacology and molecular docking., PMID:36791549
Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides., PMID:36757952
Bioinformatics and System Biology Techniques to Determine Biomolecular Signatures and Pathways of Prion Disorder., PMID:36582393
Metabolic patterns in brain 18F-fluorodeoxyglucose PET relate to aetiology in paediatric dystonia., PMID:36445406
Selection of Ideal Reference Genes for Gene Expression Analysis in COVID-19 and Mucormycosis., PMID:36377893
HPRT1 Most Suitable Reference Gene for Accurate Normalization of mRNA Expression in Canine Dermal Tissues with Radiation Therapy., PMID:36360165
Amyloid A amyloidosis on medullary sponge kidney in a 28-year-old male with gout: A case report and literature review., PMID:36346163
Abnormalities of neural stem cells in Lesch-Nyhan disease., PMID:36226509
For research use only. Not for human or drug use.
