Catalog No.
YHB86201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe2253-Glu2346
Predicted molecular weight
37.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00451
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AHF, Procoagulant component, Coagulation factor VIII, Antihemophilic factor, F8C, F8
Impact of disease activity on pregnancy outcomes and risk factors for fetal loss in systemic lupus erythematosus: a single-center cohort study., PMID:40485264
Isolation and Characterization of E8 Monoclonal Antibodies from Donors Vaccinated with Recombinant Vaccinia Vaccine with Efficient Neutralization of Authentic Monkeypox Virus., PMID:40432083
Screening of Fecal Bacteroides Strains and Discovery of Bacteroides eggerthii S13-F8 with Protective Effects Against Chemotherapy-Induced Diarrhea., PMID:40423879
Selected cell receptor genotypes differentially modulate the ABO blood group influence on Factor VIII levels in severe aortic stenosis., PMID:40398046
Characterization and Fine Mapping of the Stay-Green-Related Spot Leaf Gene TaSpl1 with Enhanced Stripe Rust and Powdery Mildew Resistance in Wheat., PMID:40362241
Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein., PMID:40350206
Cell-Based Small-Molecule Screening Identifying Proteostasis Regulators Enhancing Factor VIII Missense Mutant Secretion., PMID:40305178
[Antibiotics exacerbate Chlamydia infection of the lung and other organs and influence the gut bacterial community composition in mice]., PMID:40300869
Generation of a Severe Hemophilia A Humanized Mouse Model Capable of Inducing an Anti-FVIII Immune Response., PMID:40300593
Combined deficiency of factor V and factor VIII in a pediatric patient: a case report., PMID:40296097
How a mixture of urinary human serum albumin fragments survives in urine-mimicking pH conditions: Simulation studies., PMID:40273748
Binding of Urinary Human Serum Albumin Fragments to Albumin-Selective Aptamer-Bound Graphene Quantum Dots: Simulation Studies., PMID:40266188
A scan of pleiotropic immune mediated disease genes identifies novel determinants of baseline FVIII inhibitor status in hemophilia A., PMID:40263602
Targeting Extra Domain A of Fibronectin to Improve Noninvasive Detection of Triple-Negative Breast Cancer., PMID:40246542
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Endogenous muscarinic acetylcholine receptor signaling blunts α1-adrenergic vasoconstriction during higher-intensity handgrip exercise in humans., PMID:40235317
Rescue of a panel of Hemophilia A-causing 5'ss splicing mutations by unique Exon-specific U1snRNA variants., PMID:40148820
The bleeding edge: broadening horizons for hematopoietic stem cell therapies., PMID:40121135
Comparative Efficacy of Recombinant FVIII and Recombinant FVII Biosimilars in Severe Hemophilia A., PMID:40116719
Hemophilia is associated with accelerated biological aging., PMID:40079104
Clinical Exome Sequencing Identifies, Two Homozygous LOXHD1 Variants in Two Inbred Families With Pre-Lingual Hearing Loss From South India., PMID:40070250
Discrepancy between one-stage clotting and chromogenic factor VIII activity in women with hemophilia A and hemophilia A carriers: a retrospective clinical study., PMID:40056988
An engineered Treg selective immunocytokine induces sustained immune modulation in a preclinical model of hemophilia A., PMID:40056981
Structural basis of DNA replication fidelity of the Mpox virus., PMID:40035768
Development of a Single-Tube Reverse Transcription Real-Time PCR Assay for Diagnosis of F8 Intron 22 Inversion in Patients and Carriers of Haemophilia A., PMID:39995019
Accumulating Genetic Mutations from Primary to Secondary Biliary Tract Cancers: Analysis of Four Patients With Metachronous Biliary Tract Cancer Using Comprehensive Genomic Profiling., PMID:39993799
[Duplication of the X-chromosomal Xq28 region containing the MECP2 gene in X-linked intellectual disability syndrome Lubs-type]., PMID:39987543
CmPPR4 gene controls drought resilience in melon ecotypes., PMID:39985786
Yunpiqiangshen gel improves quality of life in dialysis patients., PMID:39957166
A new CRISPR-mediated Apc knockout allele leads to pyloric gland adenoma-like gastric polyps in mice with C57BL/6;FVB/N mixed background., PMID:39956793
Enhancing hemophilia A gene therapy by strategic F8 deletions in AAV vectors., PMID:39949501
Pilot-Scale Production of Sericin-Derived Oligopeptides (SDOs) from Yellow Silk Cocoons: Peptide Characterization and Specifications., PMID:39942094
Noninversion Variants in Sporadic Hemophilia A Originate Mostly from Females., PMID:39940661
A randomized, two-armed, double-blind, single-dose, cross-over, bioequivalence clinical trial to compare pharmacokinetic parameters and safety of recombinant human factor VIII with Fc fusion produced by AryoGen Pharmed Company versus Elocta® (reference product) in previously treated patients with severe haemophilia A., PMID:39934428
K-Carrageenan-Tapioca Starch-Based Vegetable Capsules: A Sustainable Gelatin Alternative-Compounding and Characterization Study., PMID:39921906
Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition., PMID:39856164
Innovator ranibizumab ComparEd to Biosimilar ranibizumab in combination with Expansile gas in submaculaR HemorrhaGe: the ICEBERG study., PMID:39849439
Tolerance to factor VIII in the era of nonfactor therapies: immunologic perspectives and a systematic review of the literature., PMID:39800259
Safety and efficacy of valoctocogene roxaparvovec with prophylactic glucocorticoids: 1-year results from the phase 3b, single-arm, open-label GENEr8-3 study., PMID:39800255
Accurate evaluation of factor VIII activity of efanesoctocog alfa in the presence of emicizumab., PMID:39798924
Genomic Landscape of Chromosome X Factor VIII: From Hemophilia A in Males to Risk Variants in Females., PMID:39766791
Investigation of a hemophilia family with one female hemophilia A patient and 12 male hemophilia A patients., PMID:39724248
Bone marrow stromal cell antigen 2 is broadly expressed in the different pluripotent states of human pluripotent stem cells and regulates the expression of pluripotency genes and three germ layer markers., PMID:39718725
Phytol and bilimbi phytocompounds induce thermogenic adipocyte differentiation: An in vitro study on potential anti-obesity effects., PMID:39698098
Synergistic SDT/cuproptosis therapy for liver hepatocellular carcinoma: enhanced antitumor efficacy and specific mechanisms., PMID:39696275
FVIII peptides presented on HLA-DP and identification of an A3 domain peptide binding with high affinity to the commonly expressed HLA-DP4., PMID:39665218
Genetic Diagnosis and Prenatal Diagnosis of a Rare FVIII Family With Haemophilia A., PMID:39663887
Verification and Implementation of a Bovine Chromogenic Factor VIII Assay for Hemophilia A Patients on Emicizumab Therapy., PMID:39662012
Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A., PMID:39655790
Genetic Analysis and Reproductive Interventions for Two Rare Families Affected by Severe Haemophilia A., PMID:39632590
For research use only. Not for human or drug use.
