Catalog No.
FMC86632
Species reactivity
Human, Mouse
Host species
Rat
Isotype
IgG2b, kappa
Clonality
Monoclonal
Conjugation
PE
Target
CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P05555
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
M1/70
CD11b as a diagnostic biomarker of rheumatoid arthritis and as a risk factor of periodontitis: a pilot study., PMID:40512337
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degeneration., PMID:40468324
Developing and Characterizing the Tumor-Targeting Efficiency of an Anti-EphA2-CD11b Bispecific Antibody., PMID:40434019
Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells., PMID:40381622
Inflammatory Cutaneous Reactions with Systemic CD8+ T-Cell Responses upon Photochemical Internalization of Antigens in Mice., PMID:40348329
Dendritic cell expression of MyD88 is required for rotavirus-induced B cell activation., PMID:40304491
The synergistic antitumor effect of Karanahan technology and in situ vaccination using anti-OX40 antibodies., PMID:40296901
C3-Liposome Delivery of MUC1 Peptide and TLR Agonists Enhances Adaptive Immunity and Results in Sex-Based Tumor Growth Differences., PMID:40284463
AHR Agonist ITE Boosted PD1 Antibody's Effects by Inhibiting Myeloid-Derived Cells Suppressive Cells in an Orthotopic Mouse Glioma Model., PMID:40283908
Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis., PMID:40270956
Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury., PMID:40198123
Generation and characterization of 7DC-DM1: a non-cleavable CD47-targeting antibody-drug conjugates with antitumor effects., PMID:40187444
IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas., PMID:40176156
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259
IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma., PMID:40161763
High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype., PMID:40158231
Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression., PMID:40108283
IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer., PMID:40091029
Comparison of human macrophages derived from peripheral blood and bone marrow., PMID:40073092
Differential Immune Cell Infiltration in Eosinophilic and Non-Eosinophilic CRS: Correlations With Clinical, Endoscopic, and Radiological Findings., PMID:40067202
IL-1R1 Blockade Boosts CD40 Agonist Immune Responses but Fails to Improve Efficacy or Reduce Hepatotoxicity in Pancreatic Cancer., PMID:40060615
Inactivating the Innate Immune Receptor CD11b With a First-in-Class Monoclonal Antibody Prolongs the Survival of Kidney Allografts in Nonhuman Primates., PMID:40059096
Three-dimensional tissue culture supports the structure and function of equine synovial explants over 4 days., PMID:40043680
High-dose radiation preferentially induces the clonal expansion of hematopoietic progenitor cells over mature T and B cells in mouse bone marrow., PMID:40020684
KLF2 expression in IgG plasma cells at their induction site regulates the migration program., PMID:39976598
Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1+ monocytes-derived macrophages., PMID:39919902
Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer's Disease., PMID:39918606
Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity., PMID:39911575
Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report., PMID:39845947
CD44 in myeloid cells is a major driver of liver inflammation and injury in alcohol-associated liver disease., PMID:39808819
Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8., PMID:39776899
Characterization of Dendritic Cells and Myeloid-Derived Suppressor Cells Expressing Major Histocompatibility Complex Class II in Secondary Lymphoid Organs in Systemic Lupus Erythematosus-Prone Mice., PMID:39769367
Immunotherapeutic targeting of aging-associated isoDGR motif in chronic lung inflammation., PMID:39757428
Function and Regulation of Age-Associated B Cells in Diseases., PMID:39749652
IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas., PMID:39711568
Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935
Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development., PMID:39687626
Neutrophils in the Spotlight-An Analysis of Neutrophil Function and Phenotype in ARDS., PMID:39684262
Differential neutrophil responses in murine following intraperitoneal injections of Escherichia coli and Staphylococcus aureus., PMID:39641065
CD11b deficiency attenuates the ischemia/reperfusion-induced AKI-to-CKD process by regulating macrophage polarization., PMID:39612192
Molecular Mechanisms of Curdlan-Induced Suppression of NFATc1 Expression in Osteoclasts., PMID:39606840
5-Fluorouracil Effectively Depletes Tumor Induced Myeloid Derived Suppressor Cells in 4T1 Mammary Carcinoma Model., PMID:39606677
Mechanisms of Mt.b Ag85B-Fc fusion protein against allergic asthma in mice by intranasal immunization., PMID:39549815
Tanshinone I inhibits the functions of T lymphocytes and exerts therapeutic effects on delayed-type hypersensitivity reaction via blocking STATs signaling pathways., PMID:39536856
A protocol for immunostaining of macrophages in whole-mount mouse cornea, conjunctiva, and lacrimal gland., PMID:39514390
Benzo (A) pyrene exposure alters alveolar epithelial and macrophage cells diversity and induces antioxidant responses in lungs., PMID:39506978
Antigen-specific modulation of chronic experimental autoimmune encephalomyelitis in humanized mice by TCR-like antibody targeting autoreactive T-cell epitope., PMID:39496501
Modified Hemocyanins from Rapana thomasiana and Helix aspersa Exhibit Strong Antitumor Activity in the B16F10 Mouse Melanoma Model., PMID:39452870
Evaluation of the Anti-Inflammatory/Immunomodulatory Effect of Teucrium montanum L. Extract in Collagen-Induced Arthritis in Rats., PMID:39452128
For research use only. Not for human or drug use.
